Clinical trials: Carpal Tunnel Release
Carpal Tunnel Syndrome
A Comparison of Tissue Adhesive Material and Suture as Wound-closure Techniques Following Carpal Tunnel Decompression
Participants will be randomly assigned to suture-based wound closure (n=50) or tissue adhesive-based wound closure (n=50) with two-component skin adhesive Glubran Tiss 2®.
- Trial name
- NCT05747989
- Testing
- two-component skin adhesive, Glubran Tiss 2, skin is stitched with transcutaneous nylon sutures
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- University of Split, School of Medicine
Carpal Tunnel Syndrome
Comparison of Conventional Versus Transverse Mini-Incision Technique for Carpal Tunnel Release
This study aimed at to fill the gaps by comparing the surgical outcomes of the conventional versus transverse mini-incision technique for carpal tunnel syndrome in terms of pain and functional outcomes.
- Trial name
- NCT07018011
- Testing
- Conventional open CTR, Transverse mini-incision technique
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- RESnTEC, Institute of Research
Carpal Tunnel Syndrome, Median Neuropathy
Hydrodissection With Neuroprolotherapy Versus Open Release for Carpal Tunnel Syndrome
This study is a randomized controlled, parallel-group, non-inferiority trial designed to compare ultrasound-guided hydrodissection combined with neuroprolotherapy versus open carpal tunnel release in patients with carpal tunnel…
- Trial name
- HN-CTS (NCT07576803)
- Testing
- Ultrasound-guided Hydrodissection of the Median Nerve, Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Carpal Tunnel Syndrome
Does a Different Local Anesthetic Improve Pain After Carpal Tunnel Release?
This study is being conducted to determine whether addition of a longer-acting local anesthetic to our current anesthetic protocol improves the post-operative pain after carpal tunnel release.
- Trial name
- NCT04833777
- Testing
- Local Anesthetics Lidocaine, Local Anesthetics Bupivacaine
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Carpal Tunnel Syndrome
Predictive Value of Baseline CTQ-SSS Scores for Progression to Carpal Tunnel Release Surgery: A Cohort Study
This study aims to determine the predictive value of baseline CTQ-SSS scores for progression to carpal tunnel release (CTR) surgery in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT05838963
- Testing
- CTQ-SSS scores
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ahram Canadian University
Pain After Carpal Tunnel Release
Comparison of Bupivacaine and Exparel for Carpal Tunnel Release
Carpal tunnel syndrome is one of the most common surgeries performed per year in the United States, accounting for over 600,000 surgeries. The procedure is commonly performed under light sedation and local anesthesia.
- Trial name
- NCT02141178
- Testing
- Bupivacaine, Exparel
- Where
- United States
- Sponsor
- University of Pittsburgh
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Carpal Tunnel Syndrome, Carpal Tunnel
Are There Differences in Postoperative Pain Between Bupivacaine and Lidocaine for Carpal Tunnel Release?
The goal of this clinical trial is to compare the use of bupivacaine and lidocaine as local anesthetics in carpal tunnel release surgery.
- Trial name
- NCT05697276
- Testing
- Lidocaine, Bupivacain
- Where
- Argentina
- Volunteers
- 82 people
- Sponsor
- Hospital Italiano de Buenos Aires
Carpal Tunnel Syndrome
Comparison of Long-term Outcomes Following Endoscopic or Open Surgery for Carpal Tunnel Syndrome
No randomized trials have compared long-term outcomes following endoscopic and open carpal tunnel release in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT01887145
- Testing
- Endoscopic surgery, Open surgery
- Volunteers
- 124 people
- Sponsor
- Region Skane
Carpal Tunnel Syndrome (CTS)
Effectiveness of PErcutaneous Ultrasound-guided Carpal Tunnel Release: a Non-inferiority Study With Surgery as Comparator
Carpal tunnel syndrome is a common condition caused by compression of the median nerve. Tingling in the first three or four fingers, usually at night or upon waking, is the most frequent symptom.
- Trial name
- EPEC (NCT07668310)
- Testing
- Carpal tunnel surgery, Questionnaires
- Where
- France
- Volunteers
- 7 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Carpal Tunnel Syndrome, CTS
Multicenter Prospective Trial of Office-based Carpal Tunnel Release With Ultrasound Guidance (ROBUST)
Multicenter prospective single-arm trial of subjects with symptomatic Carpal Tunnel Syndrome treated with Ultrasound Guided Carpal Tunnel Release (CTR-US) in an office-based setting.
- Trial name
- ROBUST (NCT05675046)
- Testing
- Carpal Tunnel Release with Ultrasound Guidance using the UltraGuideCTR device
- Where
- 7 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sonex Health, Inc.
Carpal Tunnel Syndrome
Dual Task During Resistance Training in CTR
Carpal tunnel syndrome (CTS) is a highly prevalent peripheral compressive neuropathy of the upper extremity. CTS is characterised by the presence of pain, tingling sensations and paraesthesia in the median nerve territory.
- Trial name
- DTRTCTR (NCT05592184)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- University of Valencia
Carpal Tunnel Syndrome, Incision
Comparing a Modified Mini-incision Approach Versus the Conventional Approach for Carpal Tunnel Release
Carpal tunnel syndrome (CTS) is the commonest nerve compression syndrome in the upper limbs, and carpal tunnel decompression is one of the most prevalent upper limb surgical interventions.
- Trial name
- NCT06114823
- Testing
- carpal tunnel release mini-incision, carpal tunnel release conventional incision
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Mansoura University
Carpal Tunnel Syndrome
Effect of Russian Current on Hand Grip Strength and Functional Outcome After Carpal Tunnel Release
this study will be conducted to investigate the effect of Russian current on hand grip strength and functional outcome after carpal tunnel release
- Trial name
- CTS (NCT07166029)
- Testing
- russian current, selected physical therapy program
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
- Trial name
- NCT05783245
- Testing
- Polarcare Machine, Standard of care ice therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Chicago
Carpal Tunnel Syndrome, PRP
PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome
This study assesses the potential benefit of adjuvant platelet-rich plasma (PRP) with carpal tunnel release (CTR) for patients with severe carpal tunnel syndrome (CTS).
- Trial name
- NCT04811287
- Testing
- Carpal Tunnel Release with Platelet-Rich Plasma, Carpal Tunnel Release without Platelet-Rich Plasma
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Michael Fredericson, MD
Carpal Tunnel
Factors Affecting Risk Recall in Open Carpal Tunnel Release Surgery
Understanding of an operation and its risks has been shown to give patients more realistic expectations, increase cooperation and result in higher satisfaction.
- Trial name
- NCT02071238
- Testing
- Pamphlet, Group Consultation
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Michael Bezuhly
Carpal Tunnel Syndrome
Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block
Carpal tunnel syndrome (CTS) is the most commonly appearing entrapment neuropathy of the upper extremity. Treatment options include both non-operative and operative methods.
- Trial name
- PERSONNEL (NCT05372393)
- Testing
- Local infiltration anaesthesia in carpal tunnel release, Distal median nerve block with local infiltration anaesthesia in carpal tunnel release
- Where
- Finland
- Volunteers
- 118 people
- Sponsor
- Kuopio University Hospital
Carpal Tunnel Syndrome
Length of Post Operative Dressing After Carpal Tunnel Release
The purpose of the study is to prospectively compare the functional, satisfaction, and wound outcomes of patients treated with one of two accepted methods of postoperative dressing following carpal tunnel release.
- Trial name
- NCT01310218
- Testing
- extended postoperative dressing, short postoperative dressing
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- UConn Health
Carpal Tunnel Syndrome
Bilateral vs Unilateral CTR
Carpal tunnel release is a well accepted treatment for median nerve compression at the wrist. With a prevalence of 50 per 1000, it is the most common compressive neuropathy.
- Trial name
- NCT01961011
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine