Clinical trials: Carpal Tunnel Release
Carpal Tunnel Syndrome, PRP
PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome
This study assesses the potential benefit of adjuvant platelet-rich plasma (PRP) with carpal tunnel release (CTR) for patients with severe carpal tunnel syndrome (CTS).
- Trial name
- NCT04811287
- Testing
- Carpal Tunnel Release with Platelet-Rich Plasma, Carpal Tunnel Release without Platelet-Rich Plasma
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Michael Fredericson, MD
Carpal Tunnel Syndrome
Comparison of Long-term Outcomes Following Endoscopic or Open Surgery for Carpal Tunnel Syndrome
No randomized trials have compared long-term outcomes following endoscopic and open carpal tunnel release in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT01887145
- Testing
- Endoscopic surgery, Open surgery
- Volunteers
- 124 people
- Sponsor
- Region Skane
Entrapment Neuropathy, Carpal Tunnel, Compression Neuropathy, Carpal Tunnel
Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial.
The postoperative course of the decompression of the median nerve in the carpal tunnel syndrome can sometimes be complicated by pain, paresthesias and other unpleasant symptoms, or may be characterized by a slow recovery of nerve…
- Conditions
- Entrapment Neuropathy, Carpal Tunnel, Compression Neuropathy, Carpal Tunnel, Median Neuropathy, Carpal Tunnel
- Trial name
- NCT01895621
- Testing
- Median nerve decompression at the wrist, Alpha lipoic acid post median nerve decompression
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Istituto Ortopedico Rizzoli
Carpal Tunnel Syndrome
A Comparison of Tissue Adhesive Material and Suture as Wound-closure Techniques Following Carpal Tunnel Decompression
Participants will be randomly assigned to suture-based wound closure (n=50) or tissue adhesive-based wound closure (n=50) with two-component skin adhesive Glubran Tiss 2®.
- Trial name
- NCT05747989
- Testing
- two-component skin adhesive, Glubran Tiss 2, skin is stitched with transcutaneous nylon sutures
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- University of Split, School of Medicine
Amyloidosis
Carpal Tunnel Release With Risk Factors for Amyloidosis
Bilateral carpal tunnel syndrome has been demonstrated in previous literature to be a warning sign for potential amyloidosis. One study has been performed in which patients with bilateral carpal tunnel syndrome underwent tissue…
- Trial name
- NCT05793320
- Testing
- Carpal Tunnel Release Surgery
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Henry Ford Health System
To Prevent Scar Formation for Patients Underwent Surgery
The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery
The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.
- Trial name
- NCT05017467
- Testing
- undefinedCentella Asiatica Extract
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Mustafa Balevi,MD
Pain, Postoperative, Carpal Tunnel Syndrome
The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release
Carpal Tunnel Syndrome patients undergoing carpal tunnel release surgery performed by the PI will receive intra-operative injections of bupivacaine (Marcaine).
- Trial name
- CTR (NCT03729375)
- Testing
- 10cc injection of bupivacaine, 20cc injection of bupivacaine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of South Florida
Carpal Tunnel Syndrome, Diabetes
Carpal Tunnel Release in Diabetic Patients
The aim of this study is to extend a previously reported 1 year follow-up on carpal tunnel release, in matched diabetic and non-diabetic patients,to compare outcomes 5 years after surgery.
- Conditions
- Carpal Tunnel Syndrome, Diabetes, Nerve Entrapment
- Trial name
- NCT01201109
- Where
- Sweden
- Volunteers
- 66 people
- Sponsor
- Skane University Hospital
Carpal Tunnel
Consecutive Series Outcomes Review of Patients Undergoing a New Single Portal Technique for Endoscopic Carpal Tunnel Release
The Purpose of this study is to report a new single portal endoscopic release technique and the sequence of the first 50 patients who underwent this release.
- Trial name
- NCT00968123
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Idiopathic Carpal Tunnel Syndrome
Comparison of Subjective Outcomes and Changes of Ultrasonographic Morphology of Median Nerves of Mini-open and Endoscopic Carpal Tunnel Release in Patients With Idiopathic Carpal Tunnel Syndrome
A few studies have shown that the mini-incision release technique decreases the pathologic swelling of the median nerve at the inlet of the carpal tunnel and increases the flattening ratio of the median nerve in the carpal…
- Trial name
- NCT01972165
- Testing
- Mini-incision carpal tunnel release, Endoscopic carpal tunnel release
- Where
- South Korea
- Volunteers
- 67 people
- Sponsor
- Yonsei University
Carpal Tunnel Syndrome
Corticosteroid Injection as a Predictor of Outcome in Carpal Tunnel Release
This study will investigate whether symptomatic improvement following carpal tunnel corticosteroid injection can be correlated to symptomatic improvement following carpal tunnel release and therefore serve as a prognostic…
- Trial name
- NCT00655915
- Testing
- Corticosteroid Injection- 1ml of Betamethasone and 1 ml of 1% Lidocaine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Vanderbilt University
Carpal Tunnel Syndrome
Preoperative Neuromobilization Exercises for Individuals With Carpal Tunnel Syndrome
Carpal tunnel syndrome is one of the major known disorders of the wrist and hand that causes pain, tingling sensations, weakness of the hand and functional limitations in daily tasks (for example: handling objects with the…
- Trial name
- NCT03582735
- Testing
- Nerve gliding exercise
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Carpal Tunnel Syndrome
Single-portal Endoscopic Carpal Tunnel Release Versus Knifelight for Carpal Tunnel Syndrome. A Randomized Control Trial
The purpose of this study is to determine whether Single-portal Endoscopic Carpal Tunnel Release (Agee technique, SmartRelease™, MicroAire) and mini-open technique (Knifelight®, Stryker) are equally effective and safe surgical…
- Trial name
- CTS-HV (NCT01756820)
- Testing
- Single-portal Endoscopic Carpal Tunnel Release (Microaire®), Knifelight
- Where
- Greece
- Sponsor
- University of Ioannina
Carpal Tunnel Syndrome
Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release
Although some surgeons prefer one technique rather than the other, both endoscopic and open carpal tunnel release procedures are accepted as standard of care surgeries to relieve carpal tunnel syndrome.
- Trial name
- NCT00880295
- Testing
- endoscopic carpal tunnel release, open carpal tunnel release
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Penn State University
Patient Satisfaction, Suture, Complication
Does Addition of a Vessel Loop in Wound Closure Improve Suture Removal?
This study will investigate whether adding a vessel loop under sutures after elective carpal tunnel release increases patient satisfaction with suture removal.
- Trial name
- NCT04339439
- Testing
- Vessel loop (FDA product code FZZ)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Carilion Clinic
Carpal Tunnel Syndrome
Carpal Tunnel Release Effects on Median Nerve Perfusion
This study aims to examine the effect of carpal tunnel release on blood flow to the median nerve using SPY scope imaging to view the perfusion to the nerve.
- Trial name
- NCT01610739
- Testing
- Indigocyanine green dye
- Where
- United States
- Sponsor
- Henry Ford Health System
Carpal Tunnel Syndrome
Early Motion Following Carpal Tunnel Release
To objectively and subjectively assess two modes of commonly employed rehabilitation and confirm a superior method to treat patients following carpal tunnel release.
- Trial name
- NCT00845325
- Testing
- Group One, Control Group Two
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Missouri-Columbia
Carpal Tunnel Syndrome, Entrapment Neuropathies
Nerve Entrapment in Diabetic Patients
The aim of this study is in a prospective, consecutive series of diabetic patients with carpal tunnel syndrome, who are then age and gender matched with non-diabetic patients having idiopathic carpal tunnel syndrome to compare…
- Conditions
- Carpal Tunnel Syndrome, Entrapment Neuropathies, Nerve Compression Syndromes, Diabetes Complications
- Trial name
- NCT00775333
- Testing
- Outcome after carpal tunnel release
- Where
- Sweden
- Volunteers
- 67 people
- Sponsor
- Skane University Hospital
Carpal Tunnel Syndrome
Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release
Hand surgeons have many options to perform carpal tunnel release surgery. Some surgeons believe that techniques are best kept simple: a mini-open incision that allows adequate exposure of the transverse carpal ligament (TCL)…
- Trial name
- NCT05325567
- Testing
- Mini open incision CTR
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Louisville
Carpal Tunnel Release
Typing Proficiency Following Carpal Tunnel Release
This study will investigate how soon a patient's typing proficiency returns to their pre-operative levels following carpal tunnel release surgery.
- Trial name
- NCT01853969
- Testing
- Typing assessment
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Vanderbilt University