Clinical trials: Carpal Tunnel Release
Carpal Tunnel
Short- to Medium-term Outcome of Minimally Invasive Carpal Tunnel Release
The aim of the study is to determine whether minimally invasive, ultrasound-guided thread carpal tunnel release leads to faster functional recovery compared to standard open and endoscopic techniques in patients with carpal…
- Trial name
- NCT06997172
- Testing
- TCTR (thread carpal tunnel release), Standard-of-care
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- University Hospital, Basel, Switzerland
Carpal Tunnel Release
Typing Proficiency Following Carpal Tunnel Release
This study will investigate how soon a patient's typing proficiency returns to their pre-operative levels following carpal tunnel release surgery.
- Trial name
- NCT01853969
- Testing
- Typing assessment
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Vanderbilt University
Carpal Tunnel Syndrome (CTS)
Electrophysiological Effects of Adjunct Low-Level Laser Therapy and Median Nerve Mobilization After Carpal Tunnel Release
This randomized controlled study investigated whether adding low-level laser therapy (LLLT) or median nerve mobilization after unilateral carpal tunnel release improves median nerve electrophysiological parameters compared with…
- Trial name
- LL-CTR (NCT07400562)
- Testing
- Gallium Arsenide (GaAs) 904-nm Low-Level Laser Device, Therapist-Supervised Median Nerve Neural Mobilization Exercises, Standard Postoperative Care
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Galala University
Complex Regional Pain Syndrome I (CRPS I), Nerve Entrapment Syndrome
Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical Study
This clinical study evaluates the effectiveness of surgical treatment in patients with upper-limb complex regional pain syndrome (CRPS) diagnosed according to the Budapest criteria.
- Trial name
- CRPS-SURG (NCT07263256)
- Testing
- Lesion-Specific Surgical Correction, Median Nerve Decompression
- Where
- Czechia
- Volunteers
- 74 people
- Sponsor
- Jitka Fricova
Carpal Tunnel Syndrome
Effect of Russian Current on Hand Grip Strength and Functional Outcome After Carpal Tunnel Release
this study will be conducted to investigate the effect of Russian current on hand grip strength and functional outcome after carpal tunnel release
- Trial name
- CTS (NCT07166029)
- Testing
- russian current, selected physical therapy program
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome (CTS), Carpal Tunnel Surgery
Evaluation by Clinical and Hand Ultrasound in Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common condition where pressure on the median nerve in the wrist causes pain, numbness, and weakness in the hand.
- Trial name
- ECHO-CTS (NCT07134361)
- Testing
- Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- University of Sao Paulo General Hospital
Carpal Tunnel Syndrome, CTS
Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)
Study to compare the safety and effectiveness of carpal tunnel release with ultrasound guidance (CTR-US) vs. mini-open carpal tunnel release (mOCTR) in patients with symptomatic carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome, CTS, Carpal Tunnel
- Trial name
- TUTOR (NCT05405218)
- Testing
- CTR with Ultrasound Guidance using the UltraGuideCTR device, mOCTR
- Where
- 12 sites in United States
- Volunteers
- 122 people
- Sponsor
- Sonex Health, Inc.
Bier Block, Dexmedetomidine
A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia
Intravenous Regional Anesthesia (IVRA) is an easy and reliable anesthetic technique for hand and forearm surgery. Its use is however limited by the presence of tourniquet pain during the surgery and the absence of postoperative…
- Conditions
- Bier Block, Dexmedetomidine, Tourniquet Pain, Carpal Tunnel
- Trial name
- NCT05342870
- Testing
- Dexmedetomidine
- Volunteers
- 23 people
- Sponsor
- American University of Beirut Medical Center
Chronic Pain, Post-operative Pain
Minocycline to Reduce Pain After Carpal Tunnel Release
The investigators are looking at whether peri-operative minocycline will reduce the duration of pain after minor hand surgery: carpal tunnel release and trigger finger release.
- Trial name
- NCT02051296
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Procedural Sedation
Ketofol Versus Fenofol as Procedural Sedation for Carpal Tunnel Release
There are different methods of anesthesia for CTR surgery. Procedural sedation will allow rapid recovery and fewer complications than regional or general anesthesia (GA).
- Trial name
- NCT04686448
- Testing
- propofol-ketamine, propofol-fentanyl
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Carpal Tunnel
Consecutive Series Outcomes Review of Patients Undergoing a New Single Portal Technique for Endoscopic Carpal Tunnel Release
The Purpose of this study is to report a new single portal endoscopic release technique and the sequence of the first 50 patients who underwent this release.
- Trial name
- NCT00968123
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Carpal Tunnel Syndrome (CTS)
Ultrasound-Guided Percutaneous Release vs. Open Surgery for Carpal Tunnel Syndrome
The goal of this clinical trial is to compare the clinical and functional outcomes of two surgical approaches for the treatment of carpal tunnel syndrome (CTS): ultrasound-guided percutaneous release of the flexor retinaculum and…
- Trial name
- NCT07230782
- Testing
- Percutaneous Ultrasound Guided Release of the Transverse Carpal Ligament, Open release surgery
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Carpal Tunnel Syndrome
Evaluation of the MANOS Carpal Tunnel Release System in Patients With Carpal Tunnel Syndrome
The MANOS device is a carpal tunnel blade used to perform carpal tunnel release (CTR). CTR is indicated for the treatment of Carpal Tunnel Syndrome when conservative therapy fails.
- Trial name
- NCT01450735
- Testing
- MANOS CTR™
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Thayer Intellectual Property, Inc.
Entrapment Neuropathy, Carpal Tunnel, Compression Neuropathy, Carpal Tunnel
Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial.
The postoperative course of the decompression of the median nerve in the carpal tunnel syndrome can sometimes be complicated by pain, paresthesias and other unpleasant symptoms, or may be characterized by a slow recovery of nerve…
- Conditions
- Entrapment Neuropathy, Carpal Tunnel, Compression Neuropathy, Carpal Tunnel, Median Neuropathy, Carpal Tunnel
- Trial name
- NCT01895621
- Testing
- Median nerve decompression at the wrist, Alpha lipoic acid post median nerve decompression
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Istituto Ortopedico Rizzoli
Carpal Tunnel Syndrome
Safety and Efficacy of Percutaneous Carpal Tunnel Release Versus Open Surgery
Hypothesis: Percutaneous ambulatory carpal tunnel release offers similar outcomes to the open approach in the theatre. Study design: Two-groups randomized single-blind interventional non-inferiority clinical trial.
- Trial name
- CATS (NCT04117516)
- Testing
- Open surgery, Percutaneous surgery
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Carpal Tunnel Syndrome (CTS)
Changes in Sleep, Fatigue, Kinesiophobia, and Upper Extremity Function After Carpal Tunnel Release
Carpal tunnel syndrome can cause hand pain, numbness, weakness, sleep disturbance, fatigue, fear of movement, and difficulty performing daily activities.
- Trial name
- CTS-RECOVER (NCT07806071)
- Testing
- Carpal Tunnel Release Surgery
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Carpal Tunnel Surgery, Median Nerve Compression
Efficacy of Proximal Median Nerve Release
A multi-center randomized controlled clinical trial which determines the efficacy of proximal median nerve release in patients with persistent proximal median nerve compression.
- Conditions
- Carpal Tunnel Surgery, Median Nerve Compression, Median Nerve Entrapment
- Trial name
- PROMER (NCT07484100)
- Testing
- Proximal median nerve release, Physiotherapy
- Where
- 2 sites in Finland
- Volunteers
- 160 people
- Sponsor
- Tampere University Hospital
Carpal Tunnel Syndrome
Patient Controlled Regional Analgesia Following Carpal Tunnel Release: A Double-Blind Study Using Distal Perineural Catheters
This study was done with the primary aim of assessing the efficacy (as calculated by pain intensity difference) of patient controlled regional analgesia (PCRA) technique against oral analgesics, which has been the standard of…
- Trial name
- NCT00678314
- Testing
- Ropivacaine 0.2%, Ropivacaine 0.75%, Normal saline
- Where
- Sweden
- Volunteers
- 88 people
- Sponsor
- Region Örebro County
Median Nerve Entrapment
Ultrasound-guided Release of the Median Nerve at the Elbow in Patients With Lacertus Syndrome
Lacertus syndrome is an orthopaedic condition that occurs when the median nerve is compressed where it passes under the lacertus fibrosus.
- Trial name
- LACECHOCHIR (NCT06678646)
- Testing
- Elbow ultrasound-guided surgery
- Where
- France
- Volunteers
- 107 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
- Trial name
- NCT05783245
- Testing
- Polarcare Machine, Standard of care ice therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Chicago