Clinical trials: Carpometacarpal (CMC) Joint Arthritis
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Carpometacarpal (CMC) Joint Arthritis
Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting
The oval-8 splint has been developed for many uses in finger pathology and trauma. It has not, however, been used to treat thumb carpometacarpal (CMC) joint arthritis.
- Trial name
- Oval-8 (NCT02266095)
- Testing
- Oval-8 Splint, Tee Pee Splint, Forearm Based Splint
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Pain, Osteoarthritis
Psychosocial Factors a Prognostic Study of Pain in Patients With CMC Osteoarthritis
In this clinical trial, females with a diagnosis of thumb CMC OA, will be recruited. The primary outcome of potential risk factors of osteoarthritis, pain and function will be measured using the demographic data, visual analog…
- Trial name
- CMC (NCT03821298)
- Testing
- Standard of Care Hand Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gannon University
Carpometacarpal (CMC) Joint Arthritis
Mini TightRope Suspensionplasty Versus Ligament Reconstruction and Tendon Interposition for Thumb Carpometacarpal Osteoarthritis
Thumb carpometacarpal osteoarthritis is a common cause of pain, weakness and functional disability. Trapeziectomy with ligament reconstruction and tendon interposition (LRTI) is considered a standard surgical procedure, whereas…
- Trial name
- NCT07698301
- Testing
- Mini tightrope suspensionplasty, Ligament Reconstruction and Tendon Interposition (LRTI)
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Theodoros Mylonas
CMC Arthritis
Predictive Outcomes for Selective Thumb Carpometacarpal Joint Denervation
Background: The thumb (or first) carpometacarpal (CMC) joint is commonly affected by osteoarthritis. Literature has reported a prevalence of 15% in women and 7% in men.
- Trial name
- NCT06467669
- Testing
- Wrist denervation procedure
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Thumb Osteoarthritis
Artificial Intelligence in Trapeziometacarpal Joint Osteoarthritis: Improving Assessment and Clinical Decision-Making
This is a retrospective cohort study utilizing radiographic and computed tomography (CT) imaging data collected during routine clinical care at Schulthess Klinik Zürich.
- Trial name
- TMCAI (NCT07148349)
- Testing
- No Intervention: Observational Cohort
- Where
- Switzerland
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Carpometacarpal (CMC) Joint Arthritis, Ganglion Cyst
The Correlation of Clinical and Ultrasonographic Findings in Dorsoradial Wrist Pain Patients: Cross Sectional Study
This study aims to investigate the correlation between ultrasonographic and clinical findings in dorsoradial wrist pain. There are several etiologies for dorsoradial wrist pain, including carpometacarpal joint arthritis, De…
- Conditions
- Carpometacarpal (CMC) Joint Arthritis, Ganglion Cyst, De Quervain Disease, Radial Neuropathy
- Trial name
- NCT06980779
- Testing
- ultrasonographic examination
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Study on Basal Joint Arthritis Prospective
The data in this prospective registry will be used 1) to define which surgical and nonoperative techniques are most effective at providing pain relief, restoring function, are cost effective, and patients are satisfied with their…
- Trial name
- NCT01376024
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Columbia University
Thumb Carpometacarpal Arthritis
Suture Fixation System Versus Tendonous Reconstruction in Carpometacarpal (CMC) Arthroplasty
Thumb carpometacarpal (CMC) arthritis affect 1 in 4 females and 1 in 12 males. Patients who fail to respond to conservative treatment may benefit from surgery; however, controversy exists over the most effective surgical…
- Trial name
- NCT01121874
- Testing
- Ligament reconstruction with suture fixation system, Ligament Reconstruction with Tendon Interposition (LRTI)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- J&M Shuler
Osteoarthritis
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the CMC joint in the hand.
- Trial name
- GRIP (NCT02391506)
- Testing
- Cartiva
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cartiva, Inc.
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Use of FlexHD as Post Trapeziectomy Spacer
The objective of this study is to show that using FlexHD® (or HADM) to fill the empty space created by removal of the trapezium improves the subject's outcome and subsequent functionality of the basilar joint arthroplasty…
- Trial name
- MTF (NCT01998594)
- Testing
- Arthroplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Osteoarthritis
CMC (Carpometacarpal) OA (Osteoarthritis) Thumb Splint Study
Osteoarthritis (OA) of the thumb carpometacarpal (CMC) joint is a common condition that is seen regularly in outpatient occupational therapy and physiotherapy departments.
- Trial name
- NCT00705146
- Testing
- Comfort Cool thumb splint by North Coast Medical, Custom made thermoplastic & neoprene splint
- Where
- 3 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of British Columbia
Osteoarthritis, Osteoarthritis Thumb Base Joint
Efficacy of a Single Injection of CTM for Post-Operative CMC Arthritis
The goal of this study is to determine the success rate of a single Carpometacarpal (CMC) thumb injection after arthroplasty surgery for primary osteoarthritis of the CMC joint.
- Conditions
- Osteoarthritis, Osteoarthritis Thumb Base Joint, Carpometacarpal Osteoarthritis, Thumb
- Trial name
- CTM CMC (NCT06171529)
- Testing
- CTM
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana Hand to Shoulder Center
Osteoarthritis
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the first CMC joint in the hand compared to LRTI.
- Trial name
- GRIP 2 (NCT03247439)
- Testing
- Cartiva
- Where
- 9 sites in United States, United Kingdom
- Volunteers
- 74 people
- Sponsor
- Cartiva, Inc.
Osteoarthritis in the Carpometacarpal (CMC) Joint
CMC-1 Replacement Arthroplasty Versus Trapeziectomy
Thumb carpometacarpal (CMC-1) osteoarthritis is a common condition causing pain and disability, particularly among middle-aged and older women. When non-operative treatment fails, surgery is indicated.
- Trial name
- NCT07583628
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Carpometacarpal (CMC) Joint Arthritis
Woodcasting Versus Thermoplast Splint in CMC Arthroplasty
This study is a prospective, randomized, nonblinded trial to evaluate patient preference in splints after having a carpometacarpal arthroplasty.
- Trial name
- Woodcast (NCT06876350)
- Testing
- Woodcasting Splint, Control (Standard treatment)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Foundation for Orthopaedic Research and Education
Osteoarthritis
Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC
This multicenter, double-blind, randomized, parallel-group, active-controlled trial will be performed in approximately 80 subjects with chronic idiopathic osteoarthritis (OA) of the first carpo-metacarpal joint (CMC).
- Trial name
- NCT00423371
- Testing
- sodium hyaluronate
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Ferring Pharmaceuticals
Carpometacarpal (CMC) Osteoarthritis
Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
The goal of this study is to investigate if a timed release steroid injection may be beneficial in treating carpometacarpal (CMC) joint (thumb) osteoarthritis. The main questions to be answered are: 1.
- Trial name
- NCT06237153
- Testing
- Triamcinolone Acetonide extended release suspension
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marie Badalamente
Osteoarthritis
Thumb Muscle Thickness and Strength in CMC Osteoarthritis
A total of 34 patients aged between 50-80 years, diagnosed with first carpometacarpal joint osteoarthritis based on hand radiographs taken within the last 3 months, will be included in the study from the Physical Therapy and…
- Trial name
- NCT06730698
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Beylikduzu State Hospital