Clinical trials: Case-control Study
Cesarean Section, Cicatrix
Subcuticular Suture Versus Staples for Closure of the Skin After Caesarean Section.
The Purpose of this study is to compare two methods for closure of the skin after caesarean section on the same patient; staples and subcuticular sutures. The study is performed on two separate groups of patients: 1.
- Trial name
- NCT01217567
- Testing
- Staples left, subcuticular suture right, Subcuticular suture left side and staples right
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Rheumatoid Arthritis
Study of Human Leukocyte Antigen (HLA) Polymorphisms in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA), affects between 0.3% and 1.0% of the population, it can lead to progressive joint destruction and severe disability.
- Trial name
- HLAPRPA (NCT01111357)
- Testing
- Collect of 10 ml of peripheric blood for DNA extraction
- Where
- Martinique
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Anxiety in Pregnancy (Disorder), Urinary Incontinence
Urinary Incontinence and Anxiety in Pregnancy
This prospective case-control study aimed to evaluate the impact of presence, and severity of urinary incontinence (UI) on pregnancy related anxiety.
- Conditions
- Anxiety in Pregnancy (Disorder), Urinary Incontinence, Quality of Life
- Trial name
- NCT04942951
- Testing
- Gynecological examination, Pelvic Organ Prolapse Quantification (POP-Q), Incontinence Consultation Questionnaire-Short Form (ICIQ-SF) questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Esin Merve Erol Koç
Ischemic Stroke
Curative Efficacy of Secondary Prevention for Patients With Ischemic Stroke Through Syndrome Differentiation of TCM
The purpose of this study is to assess the efficacy and safety of Naoxintong Capsule in the secondary prevention of ischemic stroke by the multi-center, randomized,double-blind，placebo-controlled trial design project.
- Trial name
- NCT02334969
- Testing
- Naoxintong Capsule
- Where
- 24 sites in China
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Xiaofei Yu
Haemophilia
Functional and Proprioceptive Status in Patients With Hemophilic Ankle Arthropathy
Introduction: Hemophilic ankle arthropathy is manifested by functional degenerative alterations (muscle strength deficit, mobility and proprioception), intra-articular and chronic pain. Design: Case-control study.
- Trial name
- NCT05425888
- Testing
- Hemophilia group
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Breast Cancer Detection, Dense Breast Parenchyma
Delphinus SoftVue™ ROC Reader Study
The purpose of this multi-reader, multi-case (MRMC) reader study is to evaluate reader performance when SoftVue™ automated breast ultrasound and screening mammography are combined, compared to screening mammography alone, in…
- Conditions
- Breast Cancer Detection, Dense Breast Parenchyma, Benign Breast Findings, Normal Breast Screening
- Trial name
- DMT SV RRS2 (NCT03972605)
- Testing
- Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Delphinus Medical Technologies, Inc.
Stem Cell Transplant Complications
Zinc as Enhancer in Immune Recovery After Stem Cell Transplantation for Hematological Malignancies
Patients affected by multiple myeloma undergone autologous stem cell transplantation (SCT) are enrolled at the moment of stem cell collection. They are randomized 1:1 in two groups at the moment of the graft.
- Trial name
- ZENITH (NCT03159845)
- Testing
- Zinc Sulfate Oral Product, Levofloxacin 500Mg Oral Tablet, Fluconazole 200mg tab
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Post Operative Pain
Efficient Postoperative Pain Management With Multimodal IV
Postoperative pain remains a prevalent concern despite ongoing improvements in surgical methods and pain management strategies. Opioids, while commonly prescribed, frequently lead to undesirable side effects.
- Trial name
- NCT06661746
- Testing
- Multimodal IV analgesia, epidural analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Septic Arthritis
Diagnostic Criteria for Septic Arthritis
Septic arthritis (SA) is a rare but highly disabling disease. The ideal diagnosis criteria is not well established. There is an urgent need to establish golden standard for diagnosis.
- Trial name
- NCT05790434
- Testing
- Laboratory test, History taking and physical examination, biopsy
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vestibulo-Ocular Reflex, Esports Participation
Comparison of Vestibulo-Ocular Reflex and Cognitive Functions in E-Athletes and Non-Athletes
This study aims to compare cognitive functions and functional vestibulo-ocular reflex (VOR) between e-athletes and non-athletes.
- Conditions
- Vestibulo-Ocular Reflex, Esports Participation, Cognitive Functioning
- Trial name
- NCT07211191
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yusa Basoglu
Pain Control
Trans-Abdominis Plane Block Efficacy for Post-Cesarean Section Pain
The primary aim of this study is to measure the magnitude and duration of trans-abdominis plane (TAP) block analgesia in parturients undergoing elective cesarean section with concurrent standard of care operative analgesic…
- Trial name
- NCT00945620
- Testing
- ropivicaine
- Where
- United States
- Sponsor
- Vanderbilt University
Colorectal Cancer, Early Onset Colorectal Cancer
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
An increase in early-onset colorectal cancers (eoCRC), defined as a CRC before 50 years, is confirmed globally. CRC pathogenesis has been associated with several risk factors (family history, germline pathogenic variants…
- Conditions
- Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction
- Trial name
- DEMETRA (NCT05732623)
- Testing
- Semi Quantitative Food Frequency Questionnaire (SQFFQ)
- Where
- 8 sites in United States, Finland and 4 more
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- San Raffaele University
Niemann-Pick Disease, Type C1
Study of Lithium Carbonate to Treat Niemann-Pick Type C1 Disease
This study is planned to study whether lithium carbonate has protective effect on the brain of Niemann-Pick disease type C1.
- Trial name
- NCT03201627
- Testing
- Lithium Carbonate
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Non-Alcoholic Fatty Liver Disease
Characterization and Technical Evaluation of cT1 for NASH (CATE-NASH)
The primary objective of this study is to evaluate to provide evidence to establish tightly defined cut-offs to identify patients for NASH clinical trial inclusion using cT1 and/or PDFF.
- Trial name
- NCT04341246
- Testing
- LiverMultiscan
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Perspectum
Inclusion Body Myositis
IBM Dietary Surveillance Study
The goal of this observational study is to understand how diet may influence the disease characteristics of inclusion body myositis (IBM).
- Trial name
- NCT07535996
- Testing
- Whole-Body Dual-Energy X-ray Absorptiometry, Anthropometry, Capillary Blood Sampling
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Anemia, Mortality
Impact of Adherence to Anemia Management Policy on Repeat Hospitalization in End Stage Renal Disease (ESRD)
The investigators hypothesize that the post-hospitalized patient status is characterized by subacute and reversible metabolic and hematological changes that, if addressed and treated in a timely manner, would result in a reduced…
- Trial name
- NCT01017627
- Testing
- Early anemia diagnosis and treatment, No change from normal routine
- Where
- 42 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Fresenius Medical Care North America
Pneumonia, Aspiration
Preliminary Study on the Clinical Application Value of "Showering Cells" in Diagnosing Aspiration Pneumonia
Study Design and Participants: This single-center, retrospective case-control study enrolled adult patients (18-100 years) hospitalized in the RICU of the Chinese PLA General Hospital between January 2018 and December 2024, who…
- Trial name
- NCT07707206
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Chinese PLA General Hospital
Sport Injury, Attention-deficit/Hyperactivity Disorder
Effects of Subconcussive Head Impacts on Neural Integrity and Function in ADHD
The purpose of this study is to examine the acute neural responses to subconcussive head impacts in individuals with Attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- NCT04880304
- Testing
- Soccer Heading
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Indiana University
Scapula Alata, Scapular Winging
High Resolution Ultrasound of Scapulae Alatae - a Prospective Case Control Study
Scapula alata, caused by disturbance in the scapulothoracic stabilizer muscles due to nerve injury, is a relatively rare but also underreported disease.
- Trial name
- NCT03556449
- Testing
- High resolution ultrasound
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Sándor Beniczky
Goiter
Subtotal Versus Total Thyroidectomy for Benign Goiter
The extent of thyroid resection in benign goiter is controversial. Potential advantages of TT over BST may include: one-stage removal of incidental thyroid cancer reported in up to 10% of operatively treated benign thyroid…
- Trial name
- NCT01273714
- Testing
- thyroid resection
- Where
- Poland
- Volunteers
- 8,006 people
- Sponsor
- Jagiellonian University
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