Clinical trials: Case-control Study
Colorectal Cancer
The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer
Vitamin B-6, folate and homocysteine may play a critical role in the colorectal cancer progression. This is a 4-y study and the specific aims are: 1) to compare vitamin B-6, folate and homocysteine status, oxidative stress…
- Trial name
- NCT01426490
- Testing
- Vitamin C, Vitamin B6, Folic acid
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Epithelial Ovarian Cancer
Efficacy of Letrozole in Recurrent Ovarian Cancer
Randomized phase III multicenter study investigating the role of letrozole in heavily pretreated recurrent ovarian cancer.
- Trial name
- MITO32 (NCT04421547)
- Testing
- Letrozole 2.5mg, Standard single agent chemotherapy
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
SARS-CoV-2 Infection
Burn Injuries During COVID-19 Pandemic and Its Influence on Length of Stay
Burn injuries were thought to be difficult to treat during the new corona virus epidemic. Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.
- Trial name
- NCT06330389
- Testing
- Burn Injuries Graft Surgery
- Where
- Qatar
- Volunteers
- 70 people
- Sponsor
- Hamad Medical Corporation
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Influenza
China Case Control Avian Influenza
This study will determine risk factors of human infection with avian influenza A virus, also known as bird flu virus. Certain risk factors such as exposure to poultry, travel history, health status, and other factors may affect…
- Trial name
- NCT00428753
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Invasive Candidiasis, Candidemia
Genetic Susceptibility Factors for Candidemia.
This is a prospective case-control physiopathological study, which main objective is to determine the genetic host factors predisposing to candidemia.
- Conditions
- Invasive Candidiasis, Candidemia, Genetic Predisposition to Disease
- Trial name
- NCT02841501
- Testing
- Analysis of genetic polymorphisms
- Where
- France
- Volunteers
- 453 people
- Sponsor
- University Hospital, Lille
Musculoskeletal Disease, Musculoskeletal Pain
Effectiveness of Motivational Interviewing on Return to Work in People on Sick Leave Due to Musculoskeletal Disorders
Musculoskeletal disorders are the main causes for sickness absence and disability benefits in Norway and the leading causes of disability worldwide.
- Trial name
- MI-NAV (NCT03871712)
- Testing
- Motivational interview, Stratified vocational advice
- Where
- Norway
- Volunteers
- 450 people
- Sponsor
- Oslo Metropolitan University
Rheumatoid Arthritis
Neuropathic Hand Pain in Rheumatoid Arthritis
Investigators have aimed to estimate prevalence of neuropathic hand pain in RA patients and it's relation with sleep quality and sensory thresholds. For this purpose a case-control study design was planned.
- Trial name
- NCT04839081
- Testing
- questionnaires and inventories
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Bozyaka Training and Research Hospital
Lung Diseases, Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis: a Case-control Study
To determine risk factors for idiopathic pulmonary fibrosis.
- Conditions
- Lung Diseases, Pulmonary Fibrosis, Lung Diseases, Interstitial
- Trial name
- NCT00005295
- Sponsor
- University of New Mexico
Pancreas Adenocarcinoma, Small-cell Lung Cancer
Analyzing and Solving Exceptional Long-term Survivors in Solid Tumors With Poor Prognosis
This is a retrospective, exploratory, multi-center, translational, 3 cohorts case control matched study conducted in patients harboring a solid tumor with poor prognosis who presented a long-term (case) and standard (standard)…
- Conditions
- Pancreas Adenocarcinoma, Small-cell Lung Cancer, Glioblastoma, IDH-wildtype
- Trial name
- ROSALIND (NCT06160596)
- Testing
- Long term survival multimodal analysis
- Where
- France
- Volunteers
- 1,020 people
- Sponsor
- Cure 51
Incisional Hernia, Abdominal Aortic Aneurysm
Aneurysma Hernia Study - Incidence of Incisional Hernias After Abdominal Aortic Aneurysm Repair
Principles= Prevention of incision hernias by primary closure of mid line laparotomies with the best-evidenced suture techniques.
- Trial name
- АНЕУРИЗМА (NCT02012270)
- Testing
- PRINCIPLES technique, Conventional group
- Where
- 2 sites in Poland, Serbia
- Volunteers
- 240 people
- Sponsor
- Igor Koncar
Rheumatoid Arthritis
EMDR for Persistent Pain in RA
Rationale: Around 20% of rheumatoid arthritis (RA) patients have persistent pain, despite having well-controlled disease activity.
- Trial name
- NCT05941559
- Testing
- EMDR
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Medisch Spectrum Twente
Primary Open-angle Glaucoma, Glaucoma
Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma
The glycocalyx is a fibrillary lining structure that covers the inner surface of blood vessels. Composed of glycoproteins and polysaccharides, it is an essential determinant of vascular endothelial physiology: it limits…
- Trial name
- GLAUCALYX (NCT05264818)
- Testing
- Glycocheck, Ophthalmological examinations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Non-invasive and Sensitive Faecal Bacterial Markers for Early Screening and Diagnosis of Gastric Cancer
Study of Faecal Bacteria Detection in Early Screening and Diagnosis of GC
In this clinical trial, we aim to explore the synergistic alteration of specific bacteria both in gastric mucosas and feces of gastric cancer patients for the method of non-invasive and cost-effective faecal marker detection.
- Trial name
- NCT04638959
- Testing
- collect gastric tissue and stool samples
- Where
- 10 sites in China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Schizophrenia, Caregiver Burden
Psychological Resilience and Quality of Life Among Caregivers of Patients With Schizophrenia
Schizophrenia is a severe and chronic psychiatric disorder that requires long-term care management, placing family members who serve as informal caregivers under substantial psychological, physical, and financial strain.
- Conditions
- Schizophrenia, Caregiver Burden, Quality of Life
- Trial name
- NCT07837479
- Volunteers
- 130 people
- Sponsor
- Assiut University
Medical Education, ICU
Case-Based Learning for Bedside Lung Ultrasound Teaching in ICU
This single-center randomized controlled study aims to evaluate the effectiveness of Case-Based Learning (CBL) compared with traditional teaching in clinical training of bedside lung ultrasound (BLUE) for emergency medicine…
- Conditions
- Medical Education, ICU, Emergency Medicine, Lung Ultrasound
- Trial name
- NCT07594470
- Testing
- Case-Based Learning (CBL), Traditional lecture-based teaching
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Axial Spondyloarthritis (AxSpA)
Retrospective Case-Control Study for Developing an Artificial Intelligence (AI) Tool for Lesion Detection Using Magnetic Resonance Imaging (MRI) and Clinical Variables for Early Diagnosis of Axial Spondyloarthritis (axSpA)
The goal of this observational study is to develop and validate an Artificial Intelligence (AI) tool that allows the lesion detection and early diagnosis of axial spondyloarthritis (axSpA) based on Magnetic Resonance Imaging…
- Trial name
- InnovaDetect (NCT06591481)
- Where
- 7 sites in Jordan, Saudi Arabia and 2 more
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- Ángel Alberich Bayarri
Pre-Eclampsia
Prospective Case-Control Study of Cardiovascular Changes in Pregnancy Related Hypertensive Disorders
This is a research study to understand the changes in the heart and the cardiovascular system that may occur in women who develop high blood pressure during pregnancy.
- Trial name
- ARTSEN (NCT04713228)
- Testing
- ARTSENS Pen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Lateral Patellar Compression Syndrome
Novel Method for Diagnosing Lateral Patellar Compression Syndrome Using X-ray: a Retrospective Case-Control Study
This study evaluates whether the patellar axial radiograph of lateral patellar curvature angle （LPCA）with knee flexion at 30 ° can be used as a new diagnostic surrogate of lateral patellar compression syndrome（LPCS）.
- Trial name
- NCT04454593
- Testing
- no intervention
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Peking University Third Hospital
Nutrition Disorders, Migraine Disorders
Dietary Advanced Glycation End Products and Migraine
Is dietary intake of advanced glycation different between individuals with and without migraine? Is there a difference between the groups in terms of energy and nutrients? The answers to these questions are sought.
- Trial name
- NCT05747911
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karabuk University
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