Clinical trials: Cataract Surgery
Failed Conscious Sedation During Procedure
Controlled Sedation for Cataract Surgery
This study evaluates the surgeon and patient´s satisfaction who undergoes cataract surgery using either dexmedetomidine or remifentanil as sedation
- Trial name
- NCT03401606
- Testing
- remifentanil, Dexmedetomidine
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria de Ciencias de la Salud
Cataract Senile
Venturi and Peristaltic Based Phacoemulsification in Femtosecond Laser Cataract Surgery
This study will compare two methods of vacuum (peristaltic or venturi) commonly used during the removal of a femtosecond treated cataract.
- Trial name
- NCT03970525
- Testing
- Venturi pump, Peristaltic vacuum pump
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Wendell Scott
Cataract
"A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation"
Cataract surgery is the most common surgical procedure performed on humans today. The postoperative regimen includes a combination of steroids, NSAIDs (non-steroidal anti-inflammatory drugs) and antibiotics.
- Trial name
- NCT04781335
- Testing
- Dexycu, Standard of Care post operative eye drops (steroid, antibiotic, NSAID)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Eye Institute of West Florida
Primary Open Angle Glaucoma
Electroretinogram and Retinal Vascular Changes After Cataract Surgery
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
- Trial name
- NCT05871034
- Testing
- phacoemulsification
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cataract
Evaluate the Safety and Effectiveness of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens
The objective of the study is to evaluate the safety and effectiveness of the enVista trifocal intraocular lens when implanted in the capsular bag.
- Trial name
- NCT03603600
- Testing
- enVista MX60E, enVista MX60EF
- Where
- 23 sites in United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Glaucoma, Primary Open Angle, Cataract
Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert
Randomized, controlled treatment with an intracanalicular dexamethasone (0.4mg) insert following cataract surgery with intraocular lens implant (IOL) combined with minimally invasive glaucoma surgery (MIGS), specifically iStent…
- Trial name
- NCT04465864
- Testing
- Intracanalicular Dexamethasone, 0.4 mg insert
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wolstan and Goldberg Eye Associates
Cataract
Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Comparison of the new extended depth of focus (EDOF) intraocular lens (IOL) ARTIS ACTIVE, which is designed as a twinset of IOLs, with the standard EDOF IOL AT Lara .
- Trial name
- NCT03921762
- Testing
- Cataract surgery with Artis Active IOLs, Cataract surgery with AT Lara IOLs
- Where
- Austria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Blood Coagulation Disorders
The Effect of Voltaren-ophtha 0.1% Eye Drops on INR Levels (International Normalized Ratio) in Patients Taking Warfarin
A prospective study intended to examine the effect of topical Voltaren-Ophtha 0.1% eye drops after cataract surgery on INR levels (international normalized ratio) in patients taking warfarin.
- Trial name
- NCT02782338
- Testing
- Voltaren ophtha 0.1%
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Visual Outcomes
Comparison of Clinical Outcomes in Ziemer Femtosecond Versus Conventional Phacoemulsification Surgery
This study is aimed to compare the clinical outcomes in Ziemer LDV Z8 femtosecond laser-assisted cataract surgery versus conventional phacoemulsification cataract surgery
- Trial name
- NCT03351894
- Testing
- Femtosecond laser assisted cataract surgery, Conventional phacoemulsification
- Where
- Singapore
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Singapore Eye Research Institute
Ophthalmic
Bispectral Index Monitoring In Pediatric Cataract Surgery: A Comparative Study Using Propofol-Midazolam Versus Sevoflurane Anesthesia
Ocular alignment will be studied in children having cataract surgery that will be divided into two groups, one group will be anesthetized using sevoflurane anesthesia (group A), and the other will be anesthetized by midazolam…
- Trial name
- NCT05262205
- Testing
- measuring depth of anesthesia and its relation to the globe
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Visual Impairment, Hearing Loss
Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County
This cross-sectional population-based survey will be conducted among residents aged 65 years and older in Xinxing County, Yunfu, Guangdong Province, China.
- Conditions
- Visual Impairment, Hearing Loss, Dual Sensory Impairment, Cataract
- Trial name
- NCT07694505
- Where
- China
- Volunteers
- 2,854 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Astigmatism
Prospective Evaluation of the Long-term Effectiveness of the Femtosecond Laser-assisted Arcuate Incisions
This clinical study is an open, controlled, prospective, single center, single-surgeon, post-market-clinical-follow-up study to evaluate the long-term (18 months) effectiveness of the femtolaser-assisted astigmatic keratotomy.
- Trial name
- NCT02164994
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Cataract
Topical Bromfenac for Intraoperative Miosis and Pain Reduction
To evaluate the effect of bromfenac ophthalmic solution 0.09% for reduction of intraoperative miosis and pain in patient who have undergone femtosecond laser-assisted cataract surgery.
- Trial name
- NCT03831984
- Testing
- 0,09% Bromfenac, 0,1% sodium hyaluronate
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de La Luz
Macular Holes, Visual Acuity Gain
Impact of C3F8 or SF6 Use and Length of Face-down Positioning (7 vs 14 Days Respectively) in Macular Hole Surgery
The primary purpose of the study was to compare the macular hole closure and visual acuity gain following vitrectomy using SF6 gas tamponade with 7 days of face-down positioning versus C3F8 gas tamponade with 14 days of face-down…
- Conditions
- Macular Holes, Visual Acuity Gain, Cataract, Complications
- Trial name
- NCT02073266
- Testing
- Macular hole surgery using a 25 G pars plana vitrectomy, ILM peeling, fluid-air exchange followed by air-gas exchange with SF6 or C3F8.
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Cataract
Performance of a Hydrophilic and a Hydrophobic Intraocular Lens of Similar Design
Comparison of the capsular bag performance of the RayOne Hydrophobic Aspheric with the RayOne Aspheric
- Trial name
- NCT03955796
- Testing
- Hydrophobic IOL, Non-hydrophobic IOL
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Macular, Congenital Cataract
Effects of 23-gauge Lensecotomy Combined With Anterior Vitrectomy on Macular in Children With Congenital Cataract
Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the macular development.
- Trial name
- NCT04077489
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- yin ying zhao
Cataract Surgery Experience
OSUWMC EEI Sequential Cataract Patient Experience Project
The purpose is to gauge the patients' level of comfort and anxiety for sequential cataract surgeries to assess if the second experience of cataract surgery differs from the initial experience.
- Trial name
- NCT03002688
- Testing
- Survey
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cataract
A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1%
This is a post-approval, open-label, randomized, self-controlled prospective clinical study to evaluate the safety and ocular efficacy of Dexycu in controlling postoperative ocular pain and inflammation associated with cataract…
- Trial name
- NCT04273282
- Testing
- Dexycu intracameral dexamethasone, Prednisolone Acetate
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Cataract
Assesment of Intermediate Vision After BIL Cataract Surgery
The goal of this observational study is to learn about the intermediate and near vision in patiënts who underwent cataract surgery with a specific technique, called "bag in the lens".
- Trial name
- NCT06364761
- Testing
- Bag in the lens cataract surgery
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Dry Eye Disease (DED)
Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery
To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery
- Trial name
- LaReCa (NCT07155057)
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision