Clinical trials: Cataract Surgery
Cataract Surgery Incision Leak
ReSure Sealant Pivotal Study
This is a randomized multicenter study to evaluate the safety and effectiveness of ReSure Sealant compared to sutures for preventing incision leakage within the first 7 days of cataract surgery.
- Trial name
- NCT01498224
- Testing
- ReSure Sealant, Sutures
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- Ocular Therapeutix, Inc.
Visual Impairment, Hearing Loss
Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County
This cross-sectional population-based survey will be conducted among residents aged 65 years and older in Xinxing County, Yunfu, Guangdong Province, China.
- Conditions
- Visual Impairment, Hearing Loss, Dual Sensory Impairment, Cataract
- Trial name
- NCT07694505
- Where
- China
- Volunteers
- 2,854 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Pupil Dilation Prior to Cataract Surgery In-patient, Pupil Dilation Prior to Cataract Surgery Out-patient
Preoperative Cataract Pupillary Dilation: Inpatient At The Ambulatory Surgery Center vs Outpatient Dilation Prior To Arrival At The Ambulatory Surgery Center
This study was done to compare efficacy, safety and efficiencies of various methods of pupil dilation prior to cataract surgery.
- Trial name
- NCT01169688
- Testing
- Pupil dilation with phenylephrine 10% vs cyclopentolate 2%
- Volunteers
- 50 people
- Sponsor
- Northwest Kansas Surgery Center
Cataract Surgeries
Comparison of the Concordance Between Digital Marking and Manual Marking for Toric Intraocular Lens Positioning
This cross-sectional comparative study evaluated patients from a single cataract center. In each eye, manual horizontal meridian axis line was marked on the cornea using the manual peripheral corneal marking technique (Horizontal…
- Trial name
- NCT07710963
- Testing
- Verion Digital Marking
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Ocular Inflammation and Pain
Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery
To evaluate the safety and efficacy of OTX-DP as a sustained release drug (dexamethasone) depot when placed in the canaliculus of the eyelid for the treatment of ocular inflammation and pain in subjects who have undergone…
- Trial name
- NCT01666210
- Testing
- OTX-DP (Dexamethasone punctum plug)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ocular Therapeutix, Inc.
Intraocular Inflammation
A Comparison of 0.5% Loteprednol Etabonate Versus 1% Prednisolone Acetate Following Cataract Surgery
Patients are routinely given steroid eye drops following cataract surgery. This study will compare 2 approved drops:Loteprednol Etabonate versus Prednisolone Acetate Eye drops used following cataract surgery.
- Trial name
- NCT01384266
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Associated Eye Care, Minnesota
Dry Eye, Dry Eye Disease
Strip Meniscometry in Dry Eye Evaluation
Strip meniscometry is a relatively new method for evaluating the tear meniscus. The aim of the study is to evaluate the possible effect of cataract surgery on ocular surface disease and to assess the possible benefit of strip…
- Trial name
- NCT06120894
- Testing
- Central visual acuity, Intraocular pressure measurement, Slit lamp examination
- Where
- Czechia
- Volunteers
- 21 people
- Sponsor
- University Hospital Olomouc
Corneal Astigmatism
Toric IOL vs Non-toric IOL With LRI for Corneal Astigmatism
The purpose of the study is to compare the astigmatism reducing effect of a toric intraocular lens (IOL) (model MX60T - Bausch \& Lomb) with that of limbal relaxing incisional surgery combined with a non toric IOL (model MX60 …
- Trial name
- NCT03633851
- Testing
- Toric intraocular MX60T lens, Standard MX60 plus corneal incisions
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ashford and St. Peter's Hospitals NHS Trust
Cataract
An Interocular Comparative Study of Unilateral Cataract
The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to…
- Trial name
- NCT02765230
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Sun Yat-sen University
Cataract
Revised Capsular Polishing and Its Impact on the Positioning of the Intraocular Lens and Visual Quality Following Femtosecond Laser-assisted Cataract Surgery
This study aims to investigate the impact of improved capsular polishing on the long-term stability of effective lens position (ELP) and visual quality in patients following femtosecond laser-assisted cataract surgery combined…
- Trial name
- ELPVQFLACS (NCT06517095)
- Testing
- improved capsular polishing, the conventional I/A polishing
- Where
- China
- Sponsor
- Xi'an People's Hospital (Xi'an Fourth Hospital)
Cataract Extraction
A Study of Ketorolac for the Treatment of Inflammation and Pain Associated With Cataract Surgery
This is a 16 day study to evaluate the safety and efficacy of ketorolac eye drops for the treatment of inflammation and pain associated with cataract surgery
- Trial name
- NCT00521456
- Testing
- ketorolac eye drops
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Allergan
The Comparison of IOL Formulas in Eyes With PCE≥15um Undergoing Cataract Surgery
Comparison of IOL Formulas in Eyes With PCE≥15µm
The goal of this observational study is to evaluate the long-term refractive outcomes of advanced intraocular lens (IOL) power calculation formulas in cataract patients with posterior corneal elevation (PCE ≥ 15 μm).
- Trial name
- NCT07346456
- Testing
- Intraocular lens calculation formulas
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Secondary Cataract Surgery, Aphakia
Comparison of Two Different Intraocular Lenses Implanted With Yamane Technique
In case of instability or rupture of capsular bag occurs during cataract surgery, Yamane technique is one of the options to fix intracocularlens' haptics.
- Conditions
- Secondary Cataract Surgery, Aphakia, Complicated Cataract Surgery
- Trial name
- NCT05912829
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- 2 sites in Austria
- Volunteers
- 50 people
- Sponsor
- Johannes Kepler University of Linz
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Cataract, Inflammation
Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
The objective of this clinical study is to compare the safety and efficacy of mapracorat ophthalmic suspension, 3% with its vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Conditions
- Cataract, Inflammation, Surgery
- Trial name
- NCT01591161
- Testing
- Mapracorat
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Bausch & Lomb Incorporated
Wet Macular Degeneration, Cataract Extraction
Management of Patients With Neovascular Age-related Macular Degeneration Undergoing Cataract Surgery
To-date there have been only very few studies to examine the effect of cataract surgery to patients with wet age-related macular degeneration.
- Trial name
- NCT03944070
- Testing
- Ranibizumab
- Where
- Greece
- Volunteers
- 16 people
- Sponsor
- Ophthalmica Eye Institute
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Phacotrabeculotomy Versus CCI+Phaco in Patients With Borderline Control of Intraocular Pressure
The purpose of the study is to determine whether combined cataract and glaucoma surgery (phacotrabeculotomy)is more effective in lowering intraocular pressure than cataract surgery alone in patients with borderline control of…
- Trial name
- NCT00346931
- Testing
- Phacoemulsification, implantation of intraocular lens, Phacoemulsification, Implantation of IOL, trabeculotomy
- Volunteers
- 9 people
- Sponsor
- Medical University of Vienna
DIABETIC MACULAR EDEMA
Triamcinolone vs. Laser for Diabetic Macular Edema
The purpose of this study is to determine if intravitreal triamcinolone acetonide (IVTA) injection at the time of cataract surgery will improve visual acuity and decrease post-operative swelling in diabetic patients requiring…
- Trial name
- IVTA (NCT00229931)
- Testing
- Triamcinolone acetonide, laser
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
Cataract
Safety and Efficacy of FLACS With the FEMTO LDV Z8 Laser Compared to Conventional Cataract Surgery in Chinese Patients
This trial will be designed as a multi-center randomized non-inferiority clinical trial to demonstrate safety and efficacy of the FEMTO LDV Z8 laser for cataract surgery in a Chinese population in China compared to the…
- Trial name
- Z8CAT01 (NCT03953053)
- Testing
- Femtosecond Laser Assissted Cataract Surgery
- Where
- Switzerland
- Volunteers
- 132 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Cataract, Presbyopia
Visual Results of the Acrysof IQ Vivity Toric Extended Vision Intraocular Lens
The main goal of this study is to evaluate real-world visual outcomes, rotational stability, and patient reported visual disturbances with a non-diffractive extended vision presbyopia and astigmatism correcting intraocular lens…
- Conditions
- Cataract, Presbyopia, Corneal Astigmatism
- Trial name
- NCT04652037
- Testing
- Acrysof IQ Vivity Toric Extended Vision Intraocular Lens Implantation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)