Clinical trials: Cataract and IOL Surgery
CATARACT SURGERY
Comperative Trial Between an Accommodative Iol and Monofocal Iol
a comparison of two intraocular lenses in regard of accommodative power.
- Trial name
- NCT00604305
- Testing
- Acrysof, Acuity's AIOL
- Sponsor
- Shaare Zedek Medical Center
IOL, Cataract
Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery
The goal of this post-market, prospective study at multiple clinics is to evaluate the rotational stability of the RayOne Model RAO800S non-toric monofocal intraocular lens with orientation marks in adult patients undergoing…
- Trial name
- NCT07099079
- Volunteers
- 92 people
- Sponsor
- Rayner Intraocular Lenses Limited
Cataract Surgery
Crystalline Lens Tilt Evaluation Using Swept-source Optical Coherence Tomography
The goal of this retrospective study is to quantify the physiological lens tilt of the phakic eye. The main question it aims to answer is: -What influence does misalignment or tilting of IOLs have on visual quality? Preoperative…
- Trial name
- PhysTilt (NCT05690893)
- Where
- Austria
- Volunteers
- 1,000 people
- Sponsor
- Johannes Kepler University of Linz
Cataract Senile, Dry Eye
Effect of Artificial Tears on the Parameters of the Eye and Its Impact on IOL Power Calculation for Cataract Surgery
First, preoperative biometry of the eye at the IOL Master® will be performed. Then, corneal topography will be measured at the Oculus pentacam®.
- Trial name
- IOL (NCT04706455)
- Testing
- sodium hyaluronate 0.1%, sodium hyaluronate 0.3%
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Age Related Cataracts
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a…
- Trial name
- NCT07006428
- Testing
- Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Argus Research Center, Inc.
Cataract Senile, Myopia, High-Grade
Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mm
Some parameters, such as a change in the optic tilt and axial decentration, can affect the optical characteristics of intraocular lenses (IOLs) in postoperative period, which leads to residual refractive errors and other…
- Conditions
- Cataract Senile, Myopia, High-Grade, Corneal Astigmatism
- Trial name
- NCT05129566
- Testing
- IOL Clareon AutonoMe, IOL Hoya iSert 251
- Where
- Russia
- Volunteers
- 78 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Cataract
Refractive and Visual Outcomes With the ARGOS Biometer In Eyes With a History of Refractive Surgery: ARGOS Study
The study is to evaluate the visual and refractive outcomes in eyes with prior myopic refractive surgery undergoing cataract surgery for intraocular lens (IOL) power calculations.
- Trial name
- NCT07129980
- Testing
- ARGOS Biometer
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vance Thompson Vision
Cataract
Visual Performance of Clareon Vivity and PureSee IOL
This is study to determine the visual performance of patients with age-related cataracts implanted in both eyes with either of two extended depth of focus intraocular lenses, the Clareon Vivity (Alcon Healthcare) or the PureSee…
- Trial name
- PURVI2 (NCT07165197)
- Testing
- Phacoemulsification with implantation of an extended depth of focus intraocular lens
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- OMIQ Research
Cataract, Presbyopia Correction
Evaluation Of Patient Satisfaction And Quality Of Vision After EDOF Or Trifocal IOL Implantation
Brief Summary of the Study The goal of this clinical study is to compare the quality of vision and patient satisfaction after cataract surgery using two different approaches to multifocal intraocular lenses (IOLs).
- Trial name
- TRIEDOF IOLS (NCT07295119)
- Testing
- Fusion EDOF IOL Implantation, Bilateral Trifocal IOL Implantation
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Ophthalmological Disorder
Positional Stability and Refractive Behaviour After Implantation of an IOL After Cataract Surgery
The newest generation Lucia 621 has a step vault design that is claimed to provide excellent positional and refractive predictability.
- Trial name
- NCT06069752
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Johannes Kepler University of Linz
Cataract and IOL Surgery
HUD Surgical Guidance for Toric Alignment
This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system.
- Trial name
- CG-Toric (NCT07325188)
- Testing
- Cassini Guidance
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Gainesville Eye Associates
Cataract, Corneal Astigmatism
Comparison of Toric IOL Implantation and Opposite Clear Corneal Incision During Cataract Surgery to Correct Corneal Astigmatism
With increasing demands of patients concerning refractive outcome after cataract surgery, toric intraocular lenses (IOLs) that correct corneal astigmatism have been introduced more widely to cataract surgery.
- Trial name
- NCT01763151
- Testing
- toric IOL, IOL combined with opposite clear corneal incision (OCCI)
- Where
- Austria
- Volunteers
- 55 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Irregular Astigmatism, Astigmatism
Improving Visual Quality in Patients With Irregular Corneas Using Asymmetrical Toric Intraocular Lenses
Cataract surgery in patients with irregular corneas presents unique challenges, primarily due to the high variability in keratometry and corneal tomography measurements, which complicates accurate intraocular lens (IOL)…
- Conditions
- Irregular Astigmatism, Astigmatism, Cataract and IOL Surgery
- Trial name
- VITAL (NCT07294716)
- Testing
- AMILens Individual
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Johannes Kepler University of Linz
Astigmatism
Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism
The investigational enVista IOL, Model MX60Tis equipped with toric optics and axis marks on the posterior surface to minimize the possibility of surgically induced astigmatism.
- Trial name
- NCT01852084
- Testing
- enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Bausch & Lomb Incorporated
Phacoemulsification Cataract Surgery, Capsular Tension Ring
Capsular Tension Ring With Hydrophilic Versus Hydrophobic Intraocular Lenses
This study compares three approaches to cataract surgery. Cataract surgery involves removing the eye's cloudy natural lens and replacing it with an artificial intraocular lens (IOL) to restore clear vision.
- Conditions
- Phacoemulsification Cataract Surgery, Capsular Tension Ring, IOL Implantation
- Trial name
- CTR-IOL-3ARM (NCT07842809)
- Testing
- Hydrophilic acrylic intraocular lens (Eyecryl), Capsular tension ring (Auroring CTR 11), Hydrophobic acrylic intraocular lens (AcrySof IQ)
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Benha University
Cataract
Comparison Between a Toric Monofocal and Multifocal Intraocular Lens
The primary objective of the study is to observe the rotational stability of the implant 30 minutes, one day, 6 weeks, 6 months and 12 months after the implant surgery.
- Trial name
- NCT04907318
- Testing
- Cataract surgery
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery
Controlled, open label, prospective Post Market Clinical Follow-Up, single-center clinical study to investigate visual performance after implantation of a trifocal IOL (PhysIOL Pod L GF) in patients that underwent refractive…
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT04054427
- Testing
- IOL implantation experimental
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Presbyopia
Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantation of a Medicontur Monofocal (877PAY) or a Medicontur Extended Depth of Focus (877PEY) IOL
The purpose of this multi-center, prospective, randomized, comparative clinical investigation was to evaluate and compare the visual performance at far, intermediate and near distances, the presence of photopic phenomena and…
- Conditions
- Cataract, Presbyopia, Ametropia
- Trial name
- NCT06642779
- Testing
- VFQ- 25 (Visual Function Questionnaire), Optical Biometry, Slit lamps / Fundoscopy / Biomicroscopy
- Where
- 3 sites in Hungary
- Volunteers
- 64 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Pseudoexfoliation Syndrome
Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery
To evaluate long-term intraocular lens (IOL) decentration and tilt in eyes with pseudoexfoliation syndrome (PES) following cataract surgery using Visante anterior segment OCT and iTrace Visual Function Analyzer.
- Conditions
- Cataract, Pseudoexfoliation Syndrome, Pseudophakia
- Trial name
- NCT03453827
- Testing
- no intervention
- Volunteers
- 37 people
- Sponsor
- Hospital Hietzing
Cataract and IOL Surgery, VR-based Informed Consent
VR for Cataract Anxiety Lowering Management--A RCT Study
Cataract is currently the leading cause of blindness globally, and surgery is the only effective treatment. With the advancement of medical technology, cataract surgery is usually performed under topical anesthesia, which means…
- Trial name
- VR-CALM (NCT07620821)
- Testing
- Virtual reality simulation of intraoperative audiovisual experience
- Where
- China
- Volunteers
- 223 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine