Clinical trials: Cataracts
Cataract
High-Definition 3D Visualization System for Ophthalmic Surgery
To validate a high-definition (HD) three-dimensional (3D) visualization system in cataract surgery
- Trial name
- NCT02194543
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cataract
Visual Outcomes After Implantation of a New Multifocal Intraocular Lens
This prospective nonrandomized study comprised patients with cataract, corneal astigmatism, and motivation for spectacle independence. In all cases, a Rayner M-flex® T toric Intraocular Lens will be implanted in the capsular bag.
- Trial name
- NCT01505816
- Testing
- Multifocal Intraocular Lens (RAYNER M-FLEX T TORIC IOL)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Toric Intraocular Lens Stability, Visual Quality
Toric Intraocular Lens (IOL) Implantation for Management of Cataracts
This study included cataract patients who underwent toric intraocular lens (IOL) implantation, which aimed to evaluate the stability and clinical visual quality of toric IOLs.
- Trial name
- NCT05797298
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Peribulbar Anesthesia
Atracurium Versus Atracurium and Magnesium Sulphate As Adjuvants to Local Anesthetic
To evaluate the effects of adding magnesium sulfate to atracurium with local anesthetic mixture on akinesia of globe and eyelid regarding onset and duration in cataract surgery using peribulbar technique
- Trial name
- NCT06600945
- Testing
- Cataract surgery
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dalia yousry Mohamed elsayed
Macular Edema, Cystoid, Vision Disorders
Intraoperative Dexamethasone Implant Improves Outcome of Cataract Surgery With Diabetic Macular Edema
This study is undertaken to determine the effect of intravitreal long acting dexamethasone implant, (Ozurdex®) in improving outcome of cataract surgery in patients with diabetic macular edema.
- Conditions
- Macular Edema, Cystoid, Vision Disorders, Diabetic Macular Edema, Cystoid Macular Edema Following Cataract Surgery
- Trial name
- NCT01546402
- Testing
- Dexamethasone Drug delivery system (Ozurdex), Cataract surgery
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cataract
Anesthetic and Dilating Gel for Cataract Surgery
To prepare the eye for cataract surgery, drugs must be given to the eye to allow for surgery to take place. Traditionally, dilating drops and drops containing NSAIDs (to control inflammation) are given to the patient well in…
- Trial name
- NCT00335400
- Testing
- Anesthetic Dilating Gel
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Surgery-Complications, Cataract
Improvement of the Safety of Care in Cataract Surgery Teaching on Eyesi Simulator (E3CAPS)
The aim of this project is to reduce the risks of cataract surgery using the EyeSi simulator Axis 1: to model the learning curve of novice residents in Ophthalmology who follow the training program recommended by the "Collège des…
- Trial name
- E3CAPS (NCT05722080)
- Testing
- Eyesi simulator, Sleep deprivation
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Cataracts, Presbyopia
Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens
The purpose of this study is to evaluate the safety and performance of the SBL-3 intraocular lens.
- Trial name
- NCT02487160
- Testing
- SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
- Where
- 13 sites in United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Cataract
Long Term Outcomes of Vivity Intra Ocular Lens(IOL) Versus Control
Evaluate the long-term (>1 yr) outcomes of the Vivity IOL. The investigator will use similar measurements and procedures to the ones performed on these subjects during the FDA clinical trial.
- Trial name
- REVIVE (NCT04561570)
- Testing
- Vivity ACRYSOF IQ IOL Group, ACRYSOF IQ IOL Control Group
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- John Berdahl, MD
Cataract, Presbyopia
Comparison of Two Different Optical Biometric Systems
Primary objective of this study is to evaluate and compare the measurements of two different optical biometrics systems in patients who will undergo cataract surgery or presbyopia surgery using intraocular lenses (IOL-PC).
- Conditions
- Cataract, Presbyopia, Ocular Biometry, Intraocular Lens
- Trial name
- NCT05411341
- Testing
- Argos (Alcon Laboratories, Inc.), IOLMaster 500 (Carl Zeiss Meditec AG)
- Where
- Greece
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Intraocular Inflammation
A Comparison of 0.5% Loteprednol Etabonate Versus 1% Prednisolone Acetate Following Cataract Surgery
Patients are routinely given steroid eye drops following cataract surgery. This study will compare 2 approved drops:Loteprednol Etabonate versus Prednisolone Acetate Eye drops used following cataract surgery.
- Trial name
- NCT01384266
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Associated Eye Care, Minnesota
Cataract
Veracity Surgical: A Time/Motion and Quality of Care Study
This study aims to compare the time required for surgical planning using these two methods and to explore whether differences in surgical accuracy can be identified in a small study of 40 patients.
- Trial name
- NCT04337892
- Testing
- Standard of Care4
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Cataract
A Randomized Controlled Study of Phacoemulsification by the Enlarged Internal Incision and the Regular 2.2mm Incision
Objective and Principle: To evaluate whether enlarging the incision can reduce corneal complications associated with phacoemulsification with regular 2.2 mm incision.
- Trial name
- NCT03976791
- Testing
- enlarged internal incision, regular 2.2mm incision
- Where
- China
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract, Lens Opacities
Comparison of Clinical Outcomes POD L GF vs POD F GF in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1802 (NCT03688425)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Dry Eye
Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery
To evaluate the clinical outcomes of the systemic re-esterified triglyceride (rTG) form of omega-3 fatty acids in patients with dry eye symptoms after cataract surgery
- Trial name
- NCT04411615
- Testing
- Omega 3
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Fuchs Dystrophy, Cataract
The Evaluation of Balanced Salt Solution During Cataract Surgery
This study aims to identify if the use of BSS PLUS® Sterile Intraocular Irrigating Solution as an irrigation solution leads to improved corneal outcomes vs BSS® Sterile Irrigating Solution in more compromised corneas.
- Trial name
- NCT05853978
- Testing
- BSS Plus, BSS
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Adam Fedyk, MD, FACS
Recruitment of Participants
Study of the Correlation Between Preoperative Precise Biometrics, Spatial Assessment and Postoperative Visual Quality in Cataract Patients
This study summarizes the experience of precision treatment and postoperative management of various types of cataract, and intend to further improve the quality of Clinical Cataract diagnosis and treatment.
- Trial name
- NCT04833491
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract Senile, Pseudophakia
Tecnis Eyhance Versus Rayner RayOne Study
Cataract surgery involves replacing milky lens with a plastic intraocular lens. This plastic lens can be either monofocal (fixates for distance or near without glasses), extended depth of focus (EDOF)(fixates for intermediate and…
- Trial name
- NCT04175951
- Testing
- Intraocular lens
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Cataract
A Comparison of Two Devices for Taking Measurements of the Eye to Assist in Lens Selection for Cataract Surgery
The purpose of this study is to compare the Ziemer Ophthalmic Systems AG GALILEI G6 Lens Professional to the Oculus Pentacam® AXL for taking images and measurements of the anterior segment of the eye, including the cornea, pupil…
- Trial name
- NCT03396003
- Testing
- GALILEI G6 Lens Professional, Oculus Pentacam AXL
- Where
- Switzerland
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ziemer Ophthalmic Systems AG