Clinical trials: Cataracts
Drug Action Increased
A Randomized Controlled Trial Comparing Urea Loaded Nanoparticles to Placebo: a New Concept for Cataract Management
Cataract is the leading cause of vision loss and blindness in the world,surgery is the only available option to correct the problem and the major reasons for low cataract surgical rates include low demand because of fear of…
- Trial name
- NCT03001466
- Testing
- urea-loaded nanoparticles eye drops, Balance Salt Solution eye drops
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cataract
Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)
The purpose of this study is to evaluate the safety and effectiveness of a new investigational modified light transmission monofocal intraocular lens compared to a conventional intraocular lens (IOL).
- Trial name
- NCT00747227
- Testing
- modified light transmission intraocular lens, monofocal acrylic intraocular lens
- Where
- 11 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Aphakic Eye
Comparative Study of the Tomey OA-2000, Tomey CASIA2, and the LenStar LS900
This is a prospective comparative study that will be conducted at one clinical site in the United States, in which subjects who sign an informed consent form and fulfil all inclusion and exclusion criteria, will have OCT scans…
- Conditions
- Cataract, Aphakic Eye, Pseudophakia
- Trial name
- NCT06065072
- Testing
- Optical measurement
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Tomey Corporation
Astigmatism
Rotation Stability of Toric Intraocularlens (IOL) Compared Sitting Against Lying After Cataract Operation
To assess the rotation stability of toric intraocular lenses between sitting or routine settings (sitting, going around) after cataract operation.
- Trial name
- NCT04776057
- Testing
- catarct surgery with toric intra ocular lenses
- Where
- Austria
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Dry Eye
Impact of Cataract Surgery on the Incidence and Progression of Dry Eye Disease
Relation between dry eye and cataract
- Trial name
- NCT06759168
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Assiut University
Endophthalmitis
Preoperative Topical Gatifloxacin on Anterior Chamber Cultures After Cataract Surgery
Postoperative endophthalmitis, a possible severe complication of cataract surgery, is an infection of the anterior chamber of the eye caused by bacterial contamination and colonization through surgical incisions.
- Trial name
- NCT00335231
- Testing
- gatifloxacin ophthalmic (ZYMAR)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Cataract, Presbyopia
Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens
The purpose of this study is to determine the safety and effectiveness of the IC-8 IOL implanted in one eye and a monofocal or monofocal toric IOL implanted in the fellow eye in accordance with the indication.
- Trial name
- NCT03633695
- Testing
- IC-8 IOL Group, Control Group
- Where
- 21 sites in United States
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Dry Eye Disease (DED)
Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery
To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery
- Trial name
- LaReCa (NCT07155057)
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Nuclear Sclerotic Cataract
Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls
Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear.
- Trial name
- NCT00406263
- Testing
- Scheimpflug crystalline lens photographs
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Barnes Retina Institute
Cataract
Clinical Evaluation of a 1-Piece Intraocular Lens
The aims of this study are to: Demonstrate a reduction in postoperative cylinder compared to results from the control lens Demonstrate better uncorrected distance visual acuity compared to the control lens
- Trial name
- NCT01098812
- Testing
- Tecnis ZCB00 IOL (control), Toric Intraocular lens
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Ophthalmic Diseases (Specific Types Not Restricted), Cataract
Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular Diseases
The global distribution of primary ophthalmic medical resources is uneven, and the traditional eye disease screening model has problems such as low efficiency, high cost and limited coverage.
- Conditions
- Ophthalmic Diseases (Specific Types Not Restricted), Cataract, Refraction Error, Diabetic Retinopathy (DR)
- Trial name
- NCT07003165
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract Surgery
Efficacy and Safety of Bromfenac Ophthalmic Solution
This is a safety and efficacy study of bromfenac ophthalmic solution
- Trial name
- NCT00585975
- Testing
- bromfenac ophthalmic solution
- Where
- United States
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataracts
Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
To compare the efficacy of twice-daily topical bromfenac (Xibrom) ophthalmic solution alone versus twice-daily topical Xibrom with prednisolone acetate 1% three-times daily on visual acuity and OCT measurements.
- Trial name
- NCT00698724
- Testing
- Xibrom, and Optive, Xibrom and Pred Forte
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Cataract Surgery Deneyimi, Cataract Surgery
Katarak Surgery and Care
Although cataract surgery is an effective treatment method for improving visual function, it is important to evaluate the quality of life, daily living activities, independence level and psychosocial well-being of patients in the…
- Trial name
- NCT07807761
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cataract Extraction
Microincision Versus Smallincision Combined Surgery
The purpose of this study is to compare refractive outcomes after two different types of combined cataract surgery, namely microinscision cataract surgery and smallincision cataract surgery, and sutureless 23-gauge vitrectomy in…
- Trial name
- NCT01198483
- Testing
- Combined Micro- Surgery, Combined Small-Surgery
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Cataract
Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS)
The Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS) is a 13-year study designed primarily to evaluate the safety and efficacy of a vitamin-mineral supplement (Centrum)…
- Trial name
- CTNS (NCT00309387)
- Testing
- Centrum
- Where
- Italy
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Presbyopia, Cataract
Feasibility Study of Laser Treatment of the Crystalline Lens to Correct Presbyopia
The study will evaluate whether the LensAR laser system can be used in the lens of the eye to increase the ability to read and/or see near objects
- Trial name
- NCT01062412
- Testing
- LensAR Laser System
- Where
- Philippines
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LensAR Incorporated
Cataract, Lens Opacities
Multicentric Clinical Study on Isatis TF Trifocal Intraocular Lens
The study will be a multicentric, prospective open-label ethics committee approved clinical study to investigate safety, visual outcomes, contrast sensitivity and rotational stability after bilateral implantation of Isatis TF IOL…
- Trial name
- NCT04465344
- Testing
- Implantation of trifocal IOL, Isatis TF (device under investigation), Implantation of monofocal IOL, Isatis (control device)
- Where
- 7 sites in Czechia, Spain
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Cutting Edge SAS
Cataract, Glaucoma
IOP Changes Associated With SICS and Phako
Prospective randomized trial in patients requiring cataract surgery in which IOP, angle anatomy and other demographic and clinical data are compared. Subjects randomized to both MSICS and phakoemulsification
- Trial name
- NCT02642211
- Testing
- cataract surgery
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Robin, Alan L., M.D.
Cataract, Lens Opacities
Clinical Study to Evaluate Clinical Outcomes of LuxSmart IOL as Compared With LuxGood IOL
This study is a multicentric, prospective, randomised, controlled, post-market clinical follow up (PMCF) study to investigate safety, visual outcomes and contrast sensitivity after bilateral implantation of either LuxSmart IOLs…
- Trial name
- NCT06105190
- Testing
- Implantation of premium monofocal IOL, LuxSmart (device under investigation), Implantation of monofocal IOL, LuxGood (control device)
- Where
- 8 sites in Austria, Czechia and 4 more
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Cutting Edge SAS