Clinical trials: Catastrophizing Pain
Opioid-use Disorder, Chronic Pain Syndrome
The Effect of Chronic Pain on Delay Discounting in Methadone Patients
The epidemic of opioid overdose deaths continues to rise, killing more persons in 2017 than HIV/AIDS at the height of that epidemic.
- Trial name
- NCT04473950
- Testing
- Naloxone Hydrochloride
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Fibromyalgia
Effects and Mechanisms of Pain Neuroscience Education in Patients With Fibromyalgia
This randomized controlled trials study aims, first, to determine the effectiveness of a nurse-led PNE program designed by a multidisciplinary team, compared with an active control group on pain intensity, fibromyalgia (FM)…
- Trial name
- NCT06097091
- Testing
- Self-management education, pain neuroscience education
- Where
- Taiwan
- Volunteers
- 98 people
- Sponsor
- Taipei Medical University
Catastrophizing Pain
Catastrophism Among Chronic Pain Patients in Rheumatology
Pain catastrophizing is conceptualized as a negative cognitive-affective response to anticipated or actual pain and has been associated with a number of important pain-related outcomes. The aims of this study are 1.
- Trial name
- NCT02925754
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Catastrophizing Pain, Pain
Preoperative Pain Catastrophizing and Intraoperative Analgesia Consumption
This observational study aims to evaluate the relationship between the Pain Catastrophizing Scale (PCS) and intraoperative analgesia consumption in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT06838897
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Ahmet Pece
Fibromyalgia, Fibromyalgia Syndrome
Slow Breathing and Resistance Exercise in Fibromyalgia
This randomized controlled trial investigates whether slow breathing techniques influence heart rate variability, exercise self-efficacy, and resistance exercise performance in women with fibromyalgia.
- Trial name
- Breath-fibro (NCT07404384)
- Testing
- Slow Breathing with Visual Pacer, Slow Breathing without Visual Pacer, Spontaneous Breathing (Active Control)
- Where
- 2 sites in Spain
- Volunteers
- 159 people
- Sponsor
- University of Malaga
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Lumbar Spine Degenerative Changes, Lumbar Spine Surgery
Rehabilitation With Empowered STrategies to Optimize REcovery
The main goal of this clinical trial is to understand the benefits of remotely delivered Empowered Relief in patients undergoing lumbar spine surgery.
- Trial name
- RESTORE (NCT07406997)
- Testing
- Empowered Relief, Education
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Traumatic Fracture
Influencing Factors and Their Approach of Kinesiophobia in Patients With Traumatic Fractures
This study aims to investigate the relationship between kinesiophobia and pain catastrophizing, as well as the relationship between pain catastrophizing and pain level, anxiety and depression, self-efficacy and psychological…
- Trial name
- NCT05481671
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Pain, Postoperative
Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores
This is a multiple center, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of brivoligide injection administered intrathecally before surgery in patients with high Pain Catastrophizing Scale…
- Trial name
- NCT04104919
- Testing
- Brivoligide Injection 660 mg/6 mL
- Sponsor
- Adynxx, Inc.
Familial Mediterranean Fever
The Movement Imagery Ability in Patients With Familial Mediterranean Fever
Motor imagery is the mental representation of movement without any doing body movement. A main function of imagery is to aid the self-regulation of thoughts, feelings, and behaviours.
- Trial name
- NCT04729218
- Testing
- movement imagery ability
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Chronic Low-back Pain, Catastrophizing Pain
The Effect of Combining Pain Neuroscience Education and Transcranial Direct Current Stimulation on Pain Catastrophizing, Kinesiophobia, and Pain in Patients With Chronic Low Back Pain
Recent literature has shown that individuals with persistent chronic pain often exhibit altered cognitive, affective, and sensorimotor behaviors despite a full recovery of peripheral structural injury.
- Conditions
- Chronic Low-back Pain, Catastrophizing Pain, Kinesiophobia
- Trial name
- NCT05571215
- Testing
- Transcranial Direct Current Stimulation, Pain Neuroscience Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- High Point University
Osteoarthritis, Knee
Study of Pain Catastrophizing-2 (SPAC-2)
This study experimentally manipulates pain catastrophizing in order to investigate the neural mechanisms by which pain catastrophizing influences the experience of pain in different ethnic groups among adults with knee…
- Trial name
- SPAC (NCT04805190)
- Testing
- Cognitive-Behavioral Intervention, Pain Education
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Florida
Fibromyalgia (FM)
Between Paws and Affections - Impact of Dog-Assisted Therapy in Fibromyalgia Patients
The purpose of this study is to evaluate the effectiveness and medium-term maintenance of a structured dog-assisted therapy (DAT) protocol, "Entre Patas e Afetos" (Between Paws and Affections), in reducing pain, anxiety and…
- Trial name
- IDAT26 (NCT07356206)
- Testing
- Behavioral: Dog Assisted Therapy (DAT - "Between Paws and Affections"), Behavioral: Psychoeducation and Relaxation without Dogs (Control)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- University of Minho
Systemic Lupus Erythematosus (SLE), Central Sensitization
Effectiveness of Resonance Frequency Breathing Exercises in Patients With Systemic Lupus Erythematosus and Central Sensitization
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by systemic inflammation, fatigue, central sensitization, and chronic pain.
- Conditions
- Systemic Lupus Erythematosus (SLE), Central Sensitization, Chronic Pain
- Trial name
- NCT07868289
- Testing
- Resonance Frequency Breathing, Standard Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Istanbul University - Cerrahpasa
Musculoskeletal Pain
Pain Catastrophizing as a Cause for Systemic Inflammation
Research shows that the immune system is involved in chronic pain. The immune system is involved in the process of inflammation.
- Trial name
- NCT00823147
- Testing
- Pain Catastrophizing Induction
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Beth Darnall, PhD
Chronic Pain, Chronic Pain (Back / Neck)
Chronic Pain, Emotions and Professional Football
Chronic pain is influenced by biological, psychological, and social factors, including emotions and environmental context. Prior research demonstrates that emotional states and psychosocial processes such as depression…
- Trial name
- NCT07583368
- Testing
- No Intervention: Observational Cohort
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Evidence In Motion
Catastrophizing Pain
Personalizing Preprocedural Sedation for Regional Anesthesia
This is a prospective, randomized study in patients who receive a nerve block prior to surgery. The aim is to investigate whether individual differences in psychosocial and pain profiles may play a role in how patients experience…
- Trial name
- NCT05579509
- Testing
- Midazolam and Fentanyl, Educational Reassurance
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Childhood Cancer
Pain, Body Composition and Physical Activity in Childhood Cancer.
Comparing baseline assessments of children with cancer and their parents with baseline assessments of healthy children and their parents in a case-control study will allow the investigators to make the comparison in terms of…
- Trial name
- NCT04004455
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Pain, Postoperative, Anxiety
Effect of VR on Anxiety and Pain in Gynecological Surgery
Rationale: Lack of postoperative acute pain management is associated with increased morbidity, longer recovery time, more opioid use and subsequently increased health care costs.
- Conditions
- Pain, Postoperative, Anxiety, Pain Catastrophizing, State Anxiety
- Trial name
- VRAP-G (NCT04687501)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Zuyderland Medisch Centrum
Coronary Artery Bypass Grafting, Postoperative Pain
Preoperative Pain Neuroscience Education in Patients Undergoing CABG
This randomized controlled trial evaluated the effects of a single preoperative pain neuroscience education (PNE) session on postoperative pain-related outcomes in patients undergoing elective coronary artery bypass grafting…
- Trial name
- PNE-CABG (NCT07783750)
- Testing
- Pain Neuroscience Education
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- İsmail Palalı