Clinical trials: Cathartic Colon
Chronic Constipation
Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects
This study aim was to evaluate the effect of pharmacological treatments normally used to treat functional constipation and in particular PEG, bisacodyl and prucalopride on colonic motility as assessed by high-resolution manometry.
- Trial name
- NCT03279341
- Testing
- polyethylene glycol, Bisacodyl, Prucalopride
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Colonoscopy
Safety, Efficacy, and Patient Preference of Split-Dose Crystalline Lactulose as a Preparation for Colonoscopy in Adults
The purpose of this study is to determine the efficacy of a split-dose regimen of crystalline lactulose for cleansing of the colon as a preparation for colonoscopy, as assessed by the physician's determination of the cleanliness…
- Trial name
- NCT01650870
- Testing
- Crystalline Lactulose
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Benaroya Research Institute
Cathartic Colon, Colonic Neoplasms
Different Bowel Preparations in CT Colonography: is Diet Necessary? A Randomized Controlled Trial
The aim of this study is to compare a new regimen of reduced bowel preparation that does not include low fiber diet with another reduced bowel preparation including low-fiber diet.
- Trial name
- DIETSAN (NCT02371655)
- Testing
- Diet, Faecal Tagging, Bowel cleansing
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Colorectal Cancer
Pharmacodynamic Evaluation of Stool Output Following Oral Administration of Various Low Volume PEG3350-based Gut Cleansing Solutions Using the Split Dose Intake in Healthy Subjects
This study is to investigate the effect of various modified low volume polyethylene glycol (PEG) 3350 and ascorbic acid/ascorbate (PEG+ASC)-based gut cleansing solutions on stool output in healthy subjects.
- Trial name
- OUT (NCT01834742)
- Testing
- NER1006, Moviprep
- Where
- 2 sites in Romania
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Norgine
Adenomatous Polyp, Colorectal Carcinoma
Macrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal Cancer
This randomized phase II trial studies how well macrogol 3350-based oral osmotic laxative (polyethylene glycol 3350) works in preventing cancer in patients at risk of colorectal cancer.
- Trial name
- NCT00828984
- Testing
- macrogol 3350-based oral osmotic laxative, Laboratory Biomarker Analysis
- Where
- 3 sites in United States
- Volunteers
- 87 people
- Sponsor
- National Cancer Institute (NCI)
Colonic Polyps
Cathartic-Free DECT Colonography for Detection of Colonic Polyps
Asses the clinical performance of dual-energy CTC for the detection of larger polyps 1 cm or larger without cathartic preparation.
- Trial name
- NCT00587028
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Colonoscopy Preparation
Effects and Tolerability With Clenpiq and Low Residue Diet
The Efficacy of Clenpiq utilized per FDA labeling, with a low residue diet the day before colonoscopy.
- Trial name
- NCT04150133
- Testing
- Low Residue Diet
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Hillmont GI
Cathartic Colon, Other Surgical Procedures
Appropriated Bowel Preparation Before Exploratory Laparotomy in Gynecologic Surgery
Our study perform In Department of Gynecology, Faculty of Medicine, Chiang Mai University. In our study we divide patients into 3 groups ,First group patients doing Soap suds enema (S.S.E.), second group patients doing sodium…
- Trial name
- NCT02263443
- Testing
- Soap suds enema (S.S.E.), sodium chloride enema, No enema
- Where
- Thailand
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Colon Polyp, Cathartic Colon
Short-term Effects of Bowel Preparation on Gut Microbiome in Patients Undergoing Endoscopic Colon Polypectomy
To investigate the role of different types of laxatives (compounded polyethylene glycol electrolyte dispersions and compounded sodium pico-sulfate) on the composition, evolution and recovery of the gut microbiome of patients with…
- Trial name
- NCT06339697
- Testing
- different types of laxatives (compounded polyethylene glycol electrolyte dispersions and compounded sodium pico-sulfate)
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Zhang Yanli
Colorectal Cancer
Virtual Colonoscopy Using Omnipaque as a Contrast Agent
CT colonography (CTC) is a validated screening exam for colorectal cancer. The diagnostic accuracy of CTC depends on the quality of the bowel cleansing and contrast tagging of residual stool and fluid.
- Trial name
- NCT04582500
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Irritable Bowel Syndrome
The Effects of Laxative-probiotic Sequential Treatment in the Irritable Bowel Syndrome Patients
the laxative-probiotic sequential treatment might reduce the symptoms of IBS and alter the fecal microbiota of the patients in a more robust manner .
- Trial name
- NCT02254629
- Testing
- Probiotic Clostridium Butyricum, Laxative Polyethylene Glycol
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shandong University
Cathartic Colon
Comparing Bowel Preparation Regimens for Flexible Sigmoidoscopy
Objective and Hypothesis: The investigators objective is to help determine the efficacy of oral and rectal bowel preparation regimens for sigmoidoscopy.
- Trial name
- NCT01554111
- Testing
- Picosulfate sodium,, phosphosoda rectal enema, Pico-Salax and Sodium phosphate enema
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Queen's University
Colorectal Neoplasia
Non-cathartic Computed Tomographic Colonography to Screen Subjects With a Family History of Colorectal Cancer
Background: Although subjects with first-degree relatives (FDR) with a history of colorectal cancer (CRC) are at increased risk for CRC, compliance to screening colonoscopy is suboptimal.
- Trial name
- NCT01766479
- Testing
- CT colonography
- Where
- Italy
- Volunteers
- 844 people
- Sponsor
- Istituto Clinico Humanitas
Colonic Polyps
Evaluation of Computer-assisted, Non-cathartic CT Colonography
The purpose of this study is to evaluate the performance of a non-cathartic, computer-assisted form of CT Colonography (Virtual Colonoscopy) for detection of pre-cancerous colon polyps in a group of asymptomatic screening…
- Trial name
- ncCTC (NCT01200303)
- Testing
- non-cathartic CTC
- Where
- 3 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colonic Cancer
Effect of Postoperative Laxative on Bowel Function After Colonic Surgery
Randomised doublet blinded study of the effect of tablet Magnesia (laxative) on post operative bowel ileus after open colonic resection. Material: 56 patients in two equal groups. Primary endpoint: Bowel function.
- Trial name
- NCT00427492
- Testing
- Magnesia
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Hvidovre University Hospital
Chronic Constipation
Effect to Linaclotide on Colonic Motility
This study aim was to evaluate the effect of Linaclotide, a pharmacological treatment normally used to treat functional constipation or irritable bowel syndrome with predominant constipation, on colonic motility as assessed by…
- Trial name
- NCT06989268
- Testing
- Linaclotide 290 micrograms
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Cancer
Comparison of Bowel Preparation in Virtual Colonoscopy (VC) - Patient Experience
The study will compare patient's experience between those taking a standard bowel cleansing regimen with minimal laxative tagging regimen of senna and gastrofin.
- Trial name
- NCT00460837
- Testing
- bowel preparation: senna & gastrofin versus picolax (standard)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- London North West Healthcare NHS Trust
Bowel Preparation, Efficacy, Tolerability, Safety, Colon Cancer Screening
Assessment of Safety, Quality, and Acceptance of a Bowel Preparation Using a Food Kit With Laxatives
The main purpose of this research study is to learn if an alternative bowel preparation (bowel prep) for colonoscopy is safe, tolerable and effective as compared to the standard bowel prep.
- Conditions
- Bowel Preparation, Efficacy, Tolerability, Safety, Colon Cancer Screening, Bowel Preparation for Colonoscopy
- Trial name
- NCT07605897
- Testing
- Use of a standardized meal content (food-kit) the day prior to colonoscopy, Polyethylene glycol 3350 - electrolyte solution (GoLYTELY)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Joseph Spataro
Cathartic Colon
Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
- Trial name
- NCT02761213
- Testing
- Oral sulfate solution (OSS), 2-L PEG/Asc
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Colon Cancer, Colon Polyp
Comparison of Two Preparations for the Study of the Colon Through Colonoscopy
Compare the quality of bowel preparation between two groups of patients, who will undergo two different preparations: 1. Moviprep + diet; 2. Plenvu + diet
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma, Colon Rectal Cancer
- Trial name
- NCT04497935
- Testing
- PLENVU, MoviPrep
- Where
- Portugal
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE