Clinical trials: Cathartics
Constipation
Post-Operative Constipation Following Total Knee Arthroplasty
Postoperative constipation, defined as no fully satisfying bowel movement within the first three postoperative days, is a common occurrence with some researchers estimating that between 41 and 85% of postoperative patients…
- Trial name
- NCT04380090
- Testing
- Propylene Glycol, Docusate Sodium
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Colonoscopy Preparation
Effects and Tolerability With Clenpiq and Low Residue Diet
The Efficacy of Clenpiq utilized per FDA labeling, with a low residue diet the day before colonoscopy.
- Trial name
- NCT04150133
- Testing
- Low Residue Diet
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Hillmont GI
Appendicitis, Appendicitis Acute
Clinical Study of PEG Bowel Preparation in Appendectomy Patients
Colonoscopy is a necessary item of physical examination for colorectal cancer. For high-risk groups, annual physical examination is the most effective way of early prevention; At present, a large amount of polyethylene glycol…
- Trial name
- NCT07478029
- Testing
- Bowel Preparation with Polyethylene Glycol (PEG) Laxatives
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Huaping Xie
Bowel Preparation for Colonoscopy
Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose
The objective of this study is to compare the efficacy, safety and tolerability of two bowel preparations for colonoscopy - split dose Polyethylene Glycol-Based Lavage and Pico-Salax plus Bisacodyl - with a specific emphasis on…
- Trial name
- BP (NCT01415687)
- Testing
- Polyethylene Glycol-Based Lavage, Pico-Salax (Magnesium Citrate) plus Bisacodyl
- Where
- 2 sites in Canada
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Laxative Compatibility
Sodium Picosulfate Plus Magnesium Citrate Versus Macrogol 4000 in the Bowel Cleansing Procedure: a Comparison of Efficiency and Compatibility
For effective cleansing of the bowel prior to colonoscopy polyethylene glycol (e.g. macrogol) has widely been used in Germany. Usually patients have to drink between 4 an 6 liter of macrogol in a split dose (3 liter on the day…
- Trial name
- NCT01607099
- Testing
- Compatibility
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Chronic Constipation
Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects
This study aim was to evaluate the effect of pharmacological treatments normally used to treat functional constipation and in particular PEG, bisacodyl and prucalopride on colonic motility as assessed by high-resolution manometry.
- Trial name
- NCT03279341
- Testing
- polyethylene glycol, Bisacodyl, Prucalopride
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Chronic Constipation
Effect to Linaclotide on Colonic Motility
This study aim was to evaluate the effect of Linaclotide, a pharmacological treatment normally used to treat functional constipation or irritable bowel syndrome with predominant constipation, on colonic motility as assessed by…
- Trial name
- NCT06989268
- Testing
- Linaclotide 290 micrograms
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Laxative Bowel Cleansing Solutions
Sensory Properties of Bowel Cleansing Solutions
Samples of 4 commercially available bowel cleansing solutions, namely PEG-electrolyte + ascorbic acid (PEG-Asc, Moviprep®, Norgine, UK), PEG-electrolyte (PEG, Fortrans® Ibsen, France), sodium picosulfate/magnesium citrate (SPS…
- Trial name
- NCT02642783
- Testing
- Descriptive analysis, acceptability test
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Cholecystectomy
PEG Laxatives for Intestinal Preparation and Gut Microbiota in Cholecystectomy
This observational study aims to investigate the impact of polyethylene glycol (PEG) laxatives used for bowel preparation on the gut microbiota of patients who have undergone cholecystectomy.
- Trial name
- NCT07439640
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Cathartic Colon
Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
- Trial name
- NCT02761213
- Testing
- Oral sulfate solution (OSS), 2-L PEG/Asc
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Constipation
Acupressure for Constipation in the Elderly
This study will carried out to determine the effect of acupressure applied to Tianshu (ST25), Guanyuan (CV4) and Hegu (LI4) acupuncture points for a total of 6 minutes, two to each point, on the symptoms of constipation in the…
- Trial name
- NCT05805787
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Colon Cancer, Colon Polyp
Comparison of Two Preparations for the Study of the Colon Through Colonoscopy
Compare the quality of bowel preparation between two groups of patients, who will undergo two different preparations: 1. Moviprep + diet; 2. Plenvu + diet
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma, Colon Rectal Cancer
- Trial name
- NCT04497935
- Testing
- PLENVU, MoviPrep
- Where
- Portugal
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Cathartic Colon, Colonic Neoplasms
Different Bowel Preparations in CT Colonography: is Diet Necessary? A Randomized Controlled Trial
The aim of this study is to compare a new regimen of reduced bowel preparation that does not include low fiber diet with another reduced bowel preparation including low-fiber diet.
- Trial name
- DIETSAN (NCT02371655)
- Testing
- Diet, Faecal Tagging, Bowel cleansing
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Prostate Cancer, Kidney Cancer
Preop Laxatives in Robotic Urologic Surgery
Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically.
- Conditions
- Prostate Cancer, Kidney Cancer, Constipation
- Trial name
- NCT05805436
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chad R. Tracy
Colonic Polyps
Evaluation of Computer-assisted, Non-cathartic CT Colonography
The purpose of this study is to evaluate the performance of a non-cathartic, computer-assisted form of CT Colonography (Virtual Colonoscopy) for detection of pre-cancerous colon polyps in a group of asymptomatic screening…
- Trial name
- ncCTC (NCT01200303)
- Testing
- non-cathartic CTC
- Where
- 3 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer
Virtual Colonoscopy Using Omnipaque as a Contrast Agent
CT colonography (CTC) is a validated screening exam for colorectal cancer. The diagnostic accuracy of CTC depends on the quality of the bowel cleansing and contrast tagging of residual stool and fluid.
- Trial name
- NCT04582500
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Cathartic Colon, Other Surgical Procedures
Appropriated Bowel Preparation Before Exploratory Laparotomy in Gynecologic Surgery
Our study perform In Department of Gynecology, Faculty of Medicine, Chiang Mai University. In our study we divide patients into 3 groups ,First group patients doing Soap suds enema (S.S.E.), second group patients doing sodium…
- Trial name
- NCT02263443
- Testing
- Soap suds enema (S.S.E.), sodium chloride enema, No enema
- Where
- Thailand
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Colonoscopy Preparation
Single Dose Versus Split Dose Polyethylene Glycol-based Colonic Lavage for Colonoscopy
Proper bowel cleansing prior is an essential requirement for the conduct of colonoscopy. However, due to the nature of cleansing process, the ideal bowel cleansing preparation remains elusive.
- Trial name
- NCT01610856
- Testing
- Polyethylene Glycol
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colorectal Cancer
Pharmacodynamic Evaluation of Stool Output Following Oral Administration of Various Low Volume PEG3350-based Gut Cleansing Solutions Using the Split Dose Intake in Healthy Subjects
This study is to investigate the effect of various modified low volume polyethylene glycol (PEG) 3350 and ascorbic acid/ascorbate (PEG+ASC)-based gut cleansing solutions on stool output in healthy subjects.
- Trial name
- OUT (NCT01834742)
- Testing
- NER1006, Moviprep
- Where
- 2 sites in Romania
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Norgine
Colonoscopy
Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy Procedures
Colonoscopy is the most useful exam used to evaluate colorectal diseases, like colorectal polyps and cancer. The appropriate bowel preparation is indispensable for colonoscopy procedures.
- Trial name
- NCT05076799
- Testing
- 100 ml lactulose combined with 1 L PEG, 100 ml lactulose combined with 2 L PEG, 200 ml lactulose
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sichuan University