Clinical trials: Catheter Related Blood Stream Infections
CLABSI - Central Line Associated Bloodstream Infection, Catheter-Related Blood Stream Infection
Study on the Reduction of Catheter-related Infections by Use of Self-disinfecting Venous and Arterial Access Caps
Observational study on the reduction of catheter-related Infections by use of self-disinfecting venous and arterial access caps (Curos caps ;3M, Saint Paul, MN, USA)
- Trial name
- STERILE (NCT04534348)
- Testing
- 70% isopropyl alcohol-impregnated catheter caps
- Where
- Germany
- Volunteers
- 598 people
- Sponsor
- University of Cologne
Catheter Related Blood Stream Infections, Intestinal Failure
Clinical Trial Comparing TaurolockTMHep100 (Taurolidine 1.35%) and 0.9% Saline As Prevention of Recurrent Catheter-related Bloodstream Infections
The purpose of the trial is to compare two catheter lock solutions (active: 1.35% taurolidine and placebo: 0.9% saline), on the occurence of catheter related blood stream infection, in patients with intestinal failure and a…
- Trial name
- NCT06660641
- Testing
- TaurolockTMHep100, 0.9 % saline
- Where
- Denmark
- Volunteers
- 61 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Catheter Related Blood Stream Infection
Long-term Hemodialysis Catheter Removal and Delayed Replacement, Versus Exchange Over a Guidewire to Treat Catheter Related Blood Stream Infection
Prospective, randomized Study of tunneled cuffed hemodialysis catheter removal and delayed replacement, versus exchange over a guidewire to treat catheter related blood stream infection
- Trial name
- NCT03054714
- Testing
- catheter replacement
- Volunteers
- 798 people
- Sponsor
- Ain Shams University
Hemodialysis Catheter-Associated Bacteremia, Hemodialysis Complication
Ethanol Lock and Risk of Catheter Related Blood Stream Infection in Patients With Haemodialysis Catheter
The aim of this study is to examine the effect of ethanol (70%) as lock-solution after hemodialysis on: The frequency of dialysis catheter-related bacteremia among patients under observation of potential complications Other…
- Trial name
- NCT05953675
- Testing
- Ethanol 70%, Isotonic saline with heparin
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Zealand University Hospital
Infection, Hospital, Antimicrobial
Hydrogen Peroxide and Ultraviolet Light for Disinfecting Surfaces in Intensive Care Units
Healthcare-associated infections (HAIs) remain a major problem in intensive care units (ICUs), driven by environmental contamination with multidrug-resistant organisms that persist despite routine manual cleaning.
- Conditions
- Infection, Hospital, Antimicrobial, Pneumonia Associated With Mechanical Ventilation, Urinary Tract Infection(UTI)
- Trial name
- Hylight (NCT07233837)
- Testing
- Aerosol of hydrogen peroxide, Irradiation of ultraviolet light
- Where
- 12 sites in Brazil
- Volunteers
- 5,000 people
- Sponsor
- Hospital Israelita Albert Einstein
Catheter-Related Infections
Pediatric Ethanol Lock Therapy Study.
This study is a double-blind crossover design to compare prophylaxis with ethanol lock therapy versus placebo lock therapy (heparin).
- Trial name
- NCT00948441
- Testing
- 25% ethanol, heparin lock
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pittsburgh
End Stage Renal Disease
A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis
The purpose of this study is to determine if AAT-023 (Zuragen) solution is superior to Heparin in preventing Catheter Related Blood Stream Infections for End Stage Renal Disease patients.
- Trial name
- NCT00628680
- Testing
- AAT-023 solution (Zuragen), Heparin
- Where
- 22 sites in United States
- Volunteers
- 415 people
- Sponsor
- Ash Access Technology
Catheter-Related Infections
Comparison of Chlorhexidine Impregnated Dressing and Standard Dressing
Investigators have designed a single-center randomized controlled trial to compare chlorhexidine gluconate (CHG)-impregnated dressing and standard dressing with respect to their effects on the infection outcomes.
- Trial name
- NCT04794231
- Testing
- Standard dressing, Chlorhexidine gluconate -impregnated dressing group
- Where
- Turkey (Türkiye)
- Volunteers
- 307 people
- Sponsor
- Istanbul Medeniyet University
Catheter Related Blood Stream Infections
Optimization of Therapeutic Drug Monitoring of Vancomycin in Pediatric Patients With an Implanted Port Catheter
The goal of this study is to verify whether extensive flushing of the port catheter in patients with catheter related blood stream infection will lead to correct vancomycin trough levels, taken via the port catheter and compared…
- Trial name
- NCT03720132
- Testing
- Extensive flushing of the port catheter
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lock Solution, Catheter Related Blood Stream Infections
Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative Staphylococci
Implantable venous access port infections are mainly due to coagulase negative staphylococci and may be managed by antibiotic lock therapy with retention of the port. Most of the time a vancomycin lock is used.
- Conditions
- Lock Solution, Catheter Related Blood Stream Infections, Central Venous Catheter Infection, Intravenous Drug Delivery Systems
- Trial name
- Etha-LOCK (NCT02411331)
- Testing
- Ethanol 40% + Enoxaparine 400UI/ml, Vancomycine 5 mg/ml + Héparine 2500UI/ml
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Blood Stream Infections, Short Bowel Syndrome
Evaluation of 70% Ethanol Lock Solution to Prevent Catheter Related Blood Stream Infections in Pediatric Patients
The purpose of this study is to evaluate the clinical practice of the prophylactic use of ethanol locks for the prevention of catheter related blood stream infections in pediatric intestinal rehabilitation program patients…
- Trial name
- NCT01409772
- Testing
- Ethanol Lock
- Sponsor
- University of Nebraska
Bloodstream Infection
Antimicrobial Catheter Securement Dressings for the Prevention of Cvc-related Bloodstream Infections in Cancer Patients
In neutropenic cancer patients, catheter-related bloodstream infections may cause severe infections and even death. To assess the prophylactic effect of a chlorhexidine coated catheter securement dressing on the incidence of…
- Trial name
- COAT (NCT01544686)
- Testing
- 3M™ Tegaderm™ CHG IV and 3M™ Tegaderm™ Advanced IV
- Where
- 5 sites in Germany
- Volunteers
- 630 people
- Sponsor
- University of Cologne
Infection, Hospital
Passive Disinfection Cap Compliance Study
Insertion and maintenance of central venous catheter (CVC) lines are common hospital procedures in patients, including those being treated for cancer.
- Trial name
- NCT03391960
- Testing
- Passive disinfection device
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Solventum US LLC
Blood Stream Infections, Skin Diseases, Infectious
Topical Antibiotics for Prevention of Intensive Care Unit (ICU) Central Line Infections
The purpose of the study is to determine if the overall central venous catheter related infection rate can be reduced by the application of Polysporin Triple Therapy ointment to the insertion site.
- Trial name
- ToPICL (NCT00990392)
- Testing
- Polysporin Triple Therapy ointment, Petroleum Jelly
- Where
- Canada
- Sponsor
- Fraser Health
Surgery, Central Line Associated Blood Stream Infections (CLABSI)
BIP CVC Clinical Safety and Performance Study
The primary objective of this trial was to determine Bactiguard coated BIP CVC's safety and performance and compare it to corresponding standard uncoated CVC.
- Trial name
- NCT02811380
- Testing
- BIP CVC, Uncoated Standard CVC
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Bactiguard AB
Catheter Related Blood Stream Infections
Clinical Trial With Catheter Locking TauroSept® (Taurolidine 2%) or Saline Solution 0,9%
The purpose of this study is to determine if TauroSept® taurolidine 2% is more efficient than saline solution 0.9% as a catheter lock solution in preventing catheter related blood stream infections in patients with home…
- Trial name
- NCT01826526
- Testing
- TauroSept®
- Where
- 7 sites in Denmark, Germany and 4 more
- Volunteers
- 105 people
- Sponsor
- Geert Wanten
Catheter Related Infections, Short Bowel Syndrome
Trial of 70% Ethanol Versus Heparin to Reduce the Rate of Central Line Infections in Children With Short Bowel Syndrome
This study is designed to determine if the use of 70% ethanol lock solution in central lines decreases the rate of central line infections in children with short bowel syndrome.
- Trial name
- NCT01263574
- Testing
- 70% ethanol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Hemodialysis Catheter Infection
Procalcitonin Level as a Surrogate for Catheter-related Blood Stream Bacteremia Among Hemodialysis Patients
Hemodialysis patients frequently develop catheter-related blood stream bacteremia (CRBSI). Procalcitonin is a marker of sepsis in bacterial infection. this study for detection of its role as a surrogacy marker in CRBSI.
- Trial name
- NCT03039777
- Where
- Saudi Arabia
- Volunteers
- 28 people
- Sponsor
- Benha University
Catheter Related Blood Stream Infection, Hemodialysis
Antimicrobial Locks for Hemodialysis Catheter Infections
Tunneled hemodialysis catheters are susceptible to infection with high incidence of complication to the hemodialysis patients .The study aimed to prevent catheter infection through comparing use of antimicrobial solution…
- Conditions
- Catheter Related Blood Stream Infection, Hemodialysis, Vascular Access
- Trial name
- NCT07074821
- Testing
- Taurolidine citrate 4% and heparin 500
- Where
- Oman
- Volunteers
- 100 people
- Sponsor
- Oman Ministry of Health
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland