Clinical trials: Cavities
Tooth Diseases
Clinical Evaluation of a Self-Adhering Flowable Composite in Class I Cavities
The aim of this study is to evaluate long-term clinical performance of a self-adhering flowable resin composite in comparison with a conventional flowable resin composite used with an etch\&rinse adhesive system in minimally…
- Trial name
- NCT03556553
- Testing
- Vertise Flow, LuxaFlow, Teco Adhesive
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
3D-Printed, Direct Composite
Clinical Evaluation of 3D-Printed Versus Direct Composite Restorations in Class II Cavities
The aim of this study is to clinically evaluate the performance of 3D-printed composites compared to direct conventional composite restorations in Class II cavities
- Conditions
- 3D-Printed, Direct Composite, Resin Restorations
- Trial name
- NCT07861659
- Testing
- PG4 Dentsprint 3D-printed composite resin, Filtek P60 (3M) Packable composite
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Nose Deformities, Acquired
Objectives and Measures Dimensions Nasal Resistance of Preterm and Term (MODERN)
During the resuscitation of preterm infants, withdrawal of non-invasive ventilation is difficult. In a recent study in children gestational age <30 weeks of amenorrhea (SA), definitive withdrawal rate from the first attempt to…
- Trial name
- MODERN (NCT02815345)
- Testing
- Rhinometry
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Caries, Dental
Caries Removal Methods and Microbiome Changes
Dental caries management approaches may influence not only tissue removal but also the microbial composition within the cavity. However, clinical evidence on how different caries removal methods affect the oral microbiome remains…
- Trial name
- NCT07538089
- Testing
- Non-selective caries removal, Selective caries removal
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nuh Naci Yazgan University
Recurrent Miscarriages, Habitual Abortions
Description of the Uterine Cavity in Patients With Recurrent Miscarriages
To be diagnosed with recurrent miscarriages, a couple might have a child, however experiences three or more miscarriages, primarily this happens during the first trimester.
- Trial name
- NCT02746588
- Testing
- Office hysteroscopy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Cavities of Teeth
The Effects of Bundling Dental and Medical Appointments and Price on Uptake of Preventive Dental Care
This study evaluates the effectiveness of behavioral messages sent via WhatsApp in encouraging patients to schedule preventive dental check-ups.
- Trial name
- NCT07121673
- Testing
- Dental appointment message, Dental appointment message with price discount, Bundling frame
- Where
- Chile
- Volunteers
- 306,524 people, healthy volunteers welcome
- Sponsor
- University of Chile
Breast Cancer, Colorectal Cancer
Family Quality of Life Among Families With a Member Who is a Cancer Patient
RATIONALE: Developing a questionnaire that can be used to assess the quality of life among people who have a family member with cancer may help the study of cancer in the future.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00544336
- Testing
- questionnaire administration, survey administration, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Dental Caries Class II
Clinical Performance of a Glass-ionomer Restorative System in Extended-sized Cavities
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in extended sized class II cavities.
- Trial name
- NCT02991664
- Testing
- Equia Forte, G-aenial Posterior
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Oral Cavity Carcinoma
Behavior Changing Intervention for Smokeless Tobacco and Betel Quid Use in Adolescents
Smokeless tobacco (SLT) is a known risk factor for Oral, Pharyngeal and Esophageal carcinoma. Three-quarters global SLT consumption is among the South Asian Population.
- Trial name
- NCT03488095
- Testing
- BCI for SLT and BQ Use in Adolescents: A CRT
- Where
- Pakistan
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Oral Malodor
Clinical Study on Malodor
This 3-week clinical study was designed to investigate the clinical efficacy on oral malodor of a 0.454% stannous fluoride toothpaste with nitrate and pyrophosphate (referred to as SNAP) compared to Colgate Cavity Protection…
- Trial name
- NCT06300905
- Testing
- test product, Control product
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Health
L. Brevis CD2 Strain Persistence in Oral Cavity
The aim of this study is to select the optimal conditions for quantification in the oral cavity of Lactobacillus brevis CD2, a probiotic strain contained in a commercially available dietary supplement and to assess its…
- Trial name
- NCT01782079
- Testing
- L. brevis
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Dental Caries
Evaluation of the Antibacterial Effect of Laser Diode and Zinc Oxide Nano Particles in Cavity Disinfection
this is a randomized controlled clinical trial, evaluating the antibacterial effect of laser diode and zinc oxide nano-particles when used as cavity disinfectants.Two groups, including 15 patients each, will be randomly allocated…
- Trial name
- NCT03478150
- Testing
- zinc oxide nano-particles, laser diode
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Cancer, Oral Cavity Cancer
WORST PATTERN OF INVASION IN ORAL SQUAMOUS CELL CARCINOMA
Cancer of the oral mucosa, also known as oral squamous cell carcinoma (OSCC), occurs as an ulceroproliferative lesion that can develop at any site in the mouth, from the lips to oropharynx.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Squamous Cell Carcinoma
- Trial name
- NCT05927220
- Testing
- Biopsy Specimens Histopathology
- Where
- Pakistan
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Pathology Rawalpindi
Low Back Pain
Study of Cells From Spinal Cavity of Patients With Low Back Pain
The purpose of this study to determine if cells collected give us information about what is causing a patient pain can be detected and connected with epiduroscopy images (pictures taken with a small fiber optic scope).
- Trial name
- NCT01089491
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Caries; Dentin, Dental Caries
Clinical Performance of Restorative Materials in Primary Teeth
The purpose of this study is to evaluate and compare the clinical performance of dental restorative materials in Class II cavities of primary molar teeth
- Trial name
- NCT03037814
- Testing
- Compomer, RMGIC, Giomer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Oral Cavity Squamous Cell Carcinoma, Saliva Altered
Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients
According to the World Health Organization, oral cancer (OC) is the eighth most common cancer in the world with a five year survival rate of 50%.
- Conditions
- Oral Cavity Squamous Cell Carcinoma, Saliva Altered, Precancerous Lesions
- Trial name
- OCSALTM (NCT03529604)
- Testing
- Saliva sampling, ELISA, HPLC
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Plaque, Gingivitis
Study to Investigate Toothpaste on Antibacterial Effects in the Different Regions of the Mouth
The clinical study will examine the effects of brushing with randomly assigned test toothpaste on the bacteria on the dental plaque, tongue, cheek, gum surface, and in saliva
- Trial name
- NCT07458464
- Testing
- stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste
- Where
- 2 sites in Thailand
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Cavity Squamous Cell Carcinoma, Speech Disorders
Articulatory Adaptation Following Oral Cancer Treatment
The goal of this longitudinal study is to learn more about the articulatory consequences of surgical oral cancer treatment. The main aims are to study the coordination and development of speech articulation of patients who will…
- Trial name
- SPOKE (NCT05876247)
- Testing
- Electromagnetic Articulography
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Dental Caries
European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth
The purpose of this randomized clinical trial is to compare the clinical effectiveness of three treatments involving different caries management strategies (conventional restorations, Hall technique, and Non-Restorative Caries…
- Trial name
- NCT01797458
- Testing
- Hall Technique, Non-Restorative Caries Treatment, Conventional Restoration
- Where
- 3 sites in Germany, Lithuania and 1 more
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Occlusal Caries
Clinical Performance of Flowable Giomer Versus Nanofilled Composite in Conservative Occlusal Cavities
With limited evidence-based information in literature the goal of this clinical trial is to learn about Flowable Giomer and compare it to Nanofilled Flowable Composite in Conservative Occlusal Cavities.
- Trial name
- NCT06097143
- Testing
- Flowable Giomer, Flowable Nano-filled composite with S-PRG barrier coat, Flowable Nano-filled composite
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University