Clinical trials: Celiac Disease
Non Celiac Gluten Sensitivity
Symptomatic Response to Gluten Challenge in Patients With Suspected Non Celiac Gluten Sensitivity
Non Celiac Gluten Sensitivity (NCGS) is an emergent syndrome mainly inducing gastrointestinal symptoms. NCGS is suspected to be present in the 6% of the population and thus it represents an important issue in health care.
- Trial name
- Glutox (NCT01864993)
- Testing
- gluten
- Where
- 5 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Non-celiac Gluten Sensitivity, Wheat Intolerance
Bread Study: Comparison of the Tolerance of Spelt and Wheat Bread
This project aims to verify the hypothesis that spelt products are more tolerable than bread wheat products in a target group of individuals with self-diagnosed wheat sensitivity.
- Trial name
- NCT04401956
- Testing
- bread
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Small Intestine Cancer, Celiac Disease
Enteroscopy for Early Diagnosis of Tumors in Celiac Disease
Celiac disease (CD) is the most common chronic autoimmune enteropathy in Western Countries with an estimated prevalence ranging from 1:100 to 1:200.
- Trial name
- NCT02325232
- Testing
- Capsule endoscopy, double balloon enteroscopy sequential use
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Celiac Disease
Wheat Flour Treatment With Microbial Transglutaminase and Lysine Ethyl Ester: New Frontiers in Celiac Disease Treatment.
Celiac disease is one of the most common forms of food intolerance (prevalence 1/200). The disease occurs in genetically predisposed individuals after ingestion of foods containing gluten.
- Trial name
- WHETMIT (NCT02472119)
- Testing
- rusks made of wheat flour enzymatically treated, rusks made of wheat flour not enzimatically modified, Gluten-free diet
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
Celiac Disease
Celiac Disease Database
The focus of this study is to create a database containing information about patients with celiac disease. This database will allow us to examine clinical and epidemiologic features of the University of Chicago Medical Center…
- Trial name
- NCT01172665
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- University of Chicago
Unidentified Gastrointestinal Symptoms Following Gluten-free Oats Consumption
Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 1
The research aims to investigate the effects of gluten-free oats to the gastrointestinal health in celiac disease patients and healthy subjects.
- Trial name
- NCT02764931
- Testing
- Gluten free oats and gastrointestinal health
- Where
- Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Turku
Malabsorption Syndromes, Intestinal Diseases
Long-term Health Outcomes of Screen Detected and Potential Celiac Disease Patients
The primary aim of this project is to investigate how active screening and the timing of diagnosis affect the long-term health outcomes of patients with celiac disease.
- Conditions
- Malabsorption Syndromes, Intestinal Diseases, Gastrointestinal Disease, Digestive System Diseases
- Trial name
- NCT07366151
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Tampere University Hospital
Pancreatic Cancer
Left Celiac Plexus Resection for Pancreatic Cancer at the Body and Tail
This is a prospective study of left celiac plexus resection for pancreatic cancer at the body and tail during standard distal pancreatectomy.
- Trial name
- NCT02117895
- Testing
- Celiac plexus resection, Pancreatectomy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Fudan University
Celiac Disease
A Study of Guselkumab in Adult Participants With Celiac Disease
The purpose of this study is to evaluate the safety and tolerability of guselkumab compared to placebo in participants with celiac disease.
- Trial name
- NCT04704843
- Testing
- Guselkumab
- Where
- 4 sites in United States
- Sponsor
- Janssen Research & Development, LLC
Gastrointestinal Disease, Inflammatory Bowel Diseases
Using Virtual Reality for Patients With Gastrointestinal Disease
The primary aim of this study is to evaluate the effect and impact of a technology which creates a virtual reality (VR), personalized representation of a patient's endoscopic findings in comparison our standard practice (SP).
- Trial name
- NCT03719209
- Testing
- HealthVoyager, Standard Practice
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Celiac Disease
Screen-detected Coeliac Disease, a Population Based Study
The purpose of this study is to determine the prevalence of previously undiagnosed coeliac disease based on a health survey from Tromsø, Norway. Moreover, the health impact of undiagnosed coeliac disease will be examined.
- Trial name
- NCT01695681
- Testing
- Gluten-free diet
- Where
- Norway
- Volunteers
- 172 people
- Sponsor
- University Hospital of North Norway
Not-celiac Gluten Sensitivity
Diagnostic Significance of Positive EmA Antibodies in the Duodenal Culture Medium of Not-Celiac Wheat Sensitivity (NCWS)
The most frequent diseases caused by wheat ingestion are T cell-mediated disorders, i.e. celiac disease and immunoglobulin E (IgE)-mediated allergic reactions.
- Trial name
- NCWS (NCT02203201)
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Celiac Disease, Healthy
Imaging the Duodenum Using an Optical Frequency Domain Imaging OFDI Capsule
The study is being done to assess the tolerability and feasibility of a tethered OFDI capsule to image the duodenum. A total of 108 participants (36 healthy and 72 with clinically suspected or diagnosed Celiac disease) will be…
- Trial name
- NCT02202681
- Testing
- OFDI Capsule
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Non-Celiac Gluten Sensitivity
Efficacy of Probiotic ES1 for the Treatment of Non-Celiac Gluten Sensitivity
Study to demonstrate the efficacy of Probiotic ES1 in alleviating symptoms of gluten sensitivity in non-celiac gluten sensitive subjects exposed to a small, fixed amount of gluten.
- Trial name
- NCT02810301
- Testing
- Probiotic ES1
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Exzell Pharma Inc.
Education of Patients, Counseling
Celiac Disease School for Women Living on a Gluten-free Diet
Swedish celiac disease women living on a gluten-free diet for years report poorer subjective health and more bowel complaints than Swedish women of same age in general population.
- Conditions
- Education of Patients, Counseling, Problem-Based Learning
- Trial name
- CDST (NCT01088152)
- Testing
- Celiac school, Usual care of celiac disease women
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Medical Research Council of Southeast Sweden
Dysautonomia
Temporary Celiac Ganglion Block as a Test Before Celiac Ganglion Resection for Dysautonomia-Related Bowel Dysmotility
Dysautonomia is malfunction of the autonomic nervous system. It usually results from overactivity of the sympathetic portion and over-secretion of acetylcholine.
- Trial name
- NCT04121338
- Testing
- Celiac ganglion block, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Pancreatic Ductal Adenocarcinoma, Liver, Cancer of, Primary Resectable
Celiac plExus Block to Reduce OpioID Consumption Following Hepato-pancreato-biliary Mini-invasive Surgery
The goal of this study is to assess the efficacy of intraoperative celiac plexus block (CPB) to reduce opioid consumption following laparoscopic hepato-pancreato-biliary surgery
- Trial name
- CEBOIDS (NCT06214533)
- Testing
- Ropivacaine 0.5%, Normal Saline
- Volunteers
- 60 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Autoimmune Diseases, Ulcerative Colitis
A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
The most clinically meaningful way to discover new targets of T cells in autoimmune diseases is to study the tissues of patients with active autoimmune disease mediated organ inflammation.
- Conditions
- Autoimmune Diseases, Ulcerative Colitis, Multiple Sclerosis, Scleroderma
- Trial name
- NCT06587828
- Testing
- Companion blood samples with procedure
- Where
- 11 sites in United States
- Volunteers
- 238 people
- Sponsor
- TScan Therapeutics, Inc.
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Antiphospholipid (aPL)-Positive, Rheumatic Arthritis
MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)
The primary objective of this multicenter observational registry is to characterize the clinical, epidemiological, and biological profiles of individuals of Middle Eastern, North African, and Levantine ancestry, including…
- Conditions
- Antiphospholipid (aPL)-Positive, Rheumatic Arthritis, Celiac Disease, Focal Segmental Glomerulosclerosis (FSGS)
- Trial name
- MERIT (NCT07892651)
- Where
- Jordan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Axiom Bioregistry