Clinical trials: Cell Invasion
Hepatocellular Carcinoma
The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.
To compare The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy.
- Trial name
- NCT03192618
- Testing
- adjuvant transarterial chemoinfusion (TAI), mFOLFOX6 (oxaliplatin, calcium folinate, and 5-FU)
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Sun Yat-sen University
Cutaneous Squamous Cell Carcinoma, Bowen's Disease
OCT and Invasion in Cutaneous Skin Lesions
The increasing incidence of actinic keratosis (AK), morbus Bowen (MB) and cutaneous squamous cell carcinoma (cSCC), the patients with often multiple lesions and the disadvantages of invasive diagnostics show the need for an…
- Conditions
- Cutaneous Squamous Cell Carcinoma, Bowen's Disease, Actinic Keratoses, Keratosis, Actinic
- Trial name
- NCT06014697
- Testing
- Optical Coherence Tomography, Clinical assessment
- Where
- Netherlands
- Volunteers
- 71 people
- Sponsor
- Maastricht University Medical Center
Ovarian Carcinoma
IGFBP-3 in Ovarian Cancer Invasion
An ovarian cancer cell line (OVTW-59) derived from an ovarian endometrioid carcinoma was established and its sublines, labeled as P0, P1, P2, P3, and P4 with increasing invasion abilities were selected from transwell invasion…
- Trial name
- NCT00154986
- Testing
- immunohistochemical staining, transfection, invasion assay
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Thyroid Cancer
SREBP1 as a Potential Biomarker Promotes Cell Proliferation and Invasion in Thyroid Cancer
In this study, the investigators detected the expression of SREBP1 in thyroid cancer tissues, explored the biological functions of SREBP1 in thyroid cancer cells.
- Trial name
- NCT04072731
- Testing
- pathologic
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- People's Hospital of Zhengzhou University
Placenta Previa
Management Of Placenta Previa Cases And Determination Of Hospitalization Criteria
Placenta previa cases are one of the difficult groups of patients to manage in modern obstetrics. When the literature is evaluated extensively, no clear information can be seen especially in terms of hospitalization time.
- Trial name
- NCT04264234
- Testing
- Vaginal Ultrasonography, Magnetic Resonance Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Ege University
Hepatocellular Carcinoma, Hepatic Portal Vein Tumor Invasion
TACE Plus Atezolizumab/Bevacizumab and I-125 Seeds Brachytherapy for HCC With Branch PVTT
The present study aimed to assess the effectiveness of the combination treatment of Atezolizumab/Bevacizumab, transcatheter arterial chemoembolization (TACE) and I-125 Seeds Brachytherapy (TACE-AB-I) in patients with advanced…
- Conditions
- Hepatocellular Carcinoma, Hepatic Portal Vein Tumor Invasion, Tumor Thrombus
- Trial name
- NCT05984511
- Testing
- I-125 Seeds Brachytherapy in PVTT, Transcatheter arterial chemoembolization, Atezolizumab plus Bevacizumab
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Placebo Effect, Physical Performance
Effects of Conditioning Activities in Female Athletes
This study will investigate how different warm-up strategies affect physical performance in female athletes who practice invasion sports (e.g., soccer, handball, and basketball).
- Conditions
- Placebo Effect, Physical Performance, Countermovement Jump
- Trial name
- NCT07542119
- Testing
- post-activation performance enhancement (PAPE) protocol
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Pancreatic Cancer
Feasibility Study of LUM Imaging System for Pancreatic Cancer
This single-site, non-randomized, open-label study to assess the initial safety and efficacy of the LUM Imaging System for detection of primary pancreatic cancer and peritoneal invasion from primary pancreatic cancer during…
- Trial name
- NCT04276909
- Testing
- LUM Imaging System
- Where
- United States
- Sponsor
- Lumicell, Inc.
Oral Cancer, Oral Cavity Cancer
WORST PATTERN OF INVASION IN ORAL SQUAMOUS CELL CARCINOMA
Cancer of the oral mucosa, also known as oral squamous cell carcinoma (OSCC), occurs as an ulceroproliferative lesion that can develop at any site in the mouth, from the lips to oropharynx.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Oral Squamous Cell Carcinoma
- Trial name
- NCT05927220
- Testing
- Biopsy Specimens Histopathology
- Where
- Pakistan
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Pathology Rawalpindi
Lung Cancer (NSCLC), Lung Cancer (SCLC)
Pragmatic Analysis of Complex Radiotherapy Cases In Cancer of the Lung
This study focuses on improving care for people with lung cancer who face unusual or complex treatment situations.
- Trial name
- PRACTICAL (NCT07202260)
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- The Christie NHS Foundation Trust
Surgical Infants Requiring Total Parenteral Nutrition
Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine
We hypothesise that the addition of glutamine supplementation to both parenteral nutrition and enteral feeds in surgical newborn infants leads to a reduction in bacterial invasion.
- Trial name
- NCT00647036
- Testing
- Isonitrogenous Vaminolact, Dipeptiven (L-glutamine- Lalanine)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Institute of Child Health
Bladder Urothelial Carcinoma
The Role of Pyruvate Kinase M2 in Growth, Invasion and Drug Resistance in Human Urothelial Carcinoma
Bladder urothelial carcinoma (UC) is a common malignancy and the incidence is increasing by years in Taiwan. Chemoresistance was inevitable in treatment of metastatic disease and lead to the ominous outcomes.
- Trial name
- NCT01968928
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
HCC - Hepatocellular Carcinoma, Microvascular Invasion (MVI)
Microvascular Invasion Artificial Intelligence Prediction Via Contrast-enhanced Ultrasound With Explainability
An artificial intelligence (AI) model to predict MVI of HCC using contrast-enhanced ultrasound was constructed. This model also has biological explainability.
- Trial name
- MAPUSE (NCT06760494)
- Testing
- the MAPUSE model
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- Chinese PLA General Hospital
Pancreatic Cancer
Frequency of Methods of Local Invasion of Pancreatic Adenocarcinoma
Pancreatic cancer often spreads through local invasion into local structures, including fat, blood vessels, nerves, and nearby organs (stomach, duodenum, spleen, bile duct).
- Trial name
- NCT01129167
- Where
- United States
- Volunteers
- 1,052 people
- Sponsor
- Columbia University
Endometrial Cancer, Endometrial Neoplasms
Can 3D Ultrasound be Used as an Alternative to MRI to Assess Myometrial Invasion in Endometrial Cancer?
Aim: Assess the diagnostic accuracy of 3D Ultrasound, compared to MRI and final histology with respect to myometrial invasion of endometrial cancer.
- Conditions
- Endometrial Cancer, Endometrial Neoplasms, Endometrial Hyperplasia
- Trial name
- NCT03207061
- Testing
- 3D Ultrasound
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Imperial College London
Resectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Preoperative Transarterial Chemoembolization for Resectable HCC With Portal Venous Invasion
Whether preoperative transarterial chemoembolization can prolong survival for the resectable hepatocellular carcinoma remains controversial, particularly in patients with portal vein tumor thrombi.
- Trial name
- NCT01952353
- Testing
- Preoprative TACE, Liver resection plus Thrombectomy
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Sun Yat-sen University
Pancreatic Cancer, Adult, Perineural Invasion
Neutrophil-to-lymphocyte Ratio and CA 19.9 as Predictors of Perineural Invasion in Pancreatic Cancer
Pancreatic cancer has an incidence of 1,401,450 new cases diagnosed annually worldwide and is the third leading cause of cancer-related death in Spain.
- Conditions
- Pancreatic Cancer, Adult, Perineural Invasion, Neutrophil-to-Lymphocyte Ratio, CA 19.9
- Trial name
- NCT06747481
- Where
- Spain
- Volunteers
- 323 people
- Sponsor
- University of Las Palmas de Gran Canaria
Advanced Hepatocellular Carcinoma (HCC)
A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion
In the present study, we aim to investigate the efficacy and safety of concurrent therapy of Immunotherapy based combination therapy and Radiotherapy in patients with advanced HCC showing macrovascular invasion.
- Trial name
- IOPT (NCT06828380)
- Testing
- Particle beam radiation therapy
- Where
- 2 sites in South Korea
- Volunteers
- 128 people
- Sponsor
- National Cancer Center, Korea
Bladder Cancer
Validity of Computed Tomography Versus Magnetic Resonance Imaging in Predicting Muscular Invasion of Bladder Cancer
The aim of this work is to compare validity between CT and MRI in detecting muscular invasion in Patients with bladder cancer.
- Trial name
- NCT06046469
- Testing
- CT with contrast, MRI pelvis, TURBT
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Menoufia University
Tongue Cancer, Floor of Mouth Squamous Cell Carcinoma
Ultrasound in Tongue Cancer- a Help to Decide Depth of Invasion and to Improve the Surgical Margin
The purpose of this study is to investigate if ultrasound can be helpful in the diagnostic work-up of oral tongue and floor of the mouth cancer.
- Trial name
- NCT04059861
- Testing
- Ultrasound
- Where
- Sweden
- Volunteers
- 42 people
- Sponsor
- Region Örebro County