Clinical trials: Central Venous Catheters
Central Venous Catheters, Catheter Complications
Complications Associated With Multiple Central Venous Accesses in the Internal Jugular Vein
Patients at risk of significant intraoperative blood loss and/or potential hemodynamic instability often necessitate the placement of two or more central venous catheters, including large bore catheters.
- Conditions
- Central Venous Catheters, Catheter Complications, Catheter Related Complication
- Trial name
- NCT06466226
- Testing
- Multiple central venous lines in two sites separately, Multiple central venous lines in one site (internal jugular vein)
- Volunteers
- 156 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Catheter Complications, Thrombosis
Comparison Between Sutureless Devices for PICC and a New System KT FIX PLUS
PICC (Peripherally Inserted Central Catheter) are commun used. Just one paper report morbidity with suture as fixation system for PICC (dislodgement, infection) In the guidelines it's recommended to use sutureless device.
- Conditions
- Catheter Complications, Thrombosis, Displacement of Infusion Catheter, Quality of Life
- Trial name
- KTFIXPICC (NCT02805335)
- Testing
- KTFIX PLUS
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Cardiac and Pulmonary Complications. Central Venous Line Insertion. Gastrointestinal Recovery
Trial Comparing Routine Intraoperative Transesophageal Echocardiography During Radical Cystectomy to Standard of Care
This is a prospective randomized controlled trial looking at the utility of intraoperative transesophageal echocardiography (TEE) on clinical outcomes after radical cystectomy.
- Trial name
- NCT03058250
- Testing
- Transesophageal echocardiography
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Central Line Complication, Thrombosis, Venous
The Use of Thrombin Generation Assay in Detection of Central Line Related Thrombosis (CRT) in Critically Ill Patients
To study thrombin generation parameters in critically ill patients with and without central line related thrombosis (CRT).
- Trial name
- THROM-CRIT (NCT06094387)
- Testing
- Thrombin generation assay
- Where
- Hong Kong
- Volunteers
- 2 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Vascular Access Complication
Central Line Placement-EVALUATION OF LINE DEPTH AS A FACTOR IN NEED FOR LINE REPLACEMENT SECONDARY TO MALPOSITION
This is a single center, randomized, controlled trial in which tunneled central line catheters will be placed in two distinct, select positions.
- Trial name
- NCT02602665
- Testing
- Shallow catheter tip placement, Deep catheter tip placement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Valvular Heart Disease
Comparison of Goal-directed Algorithms of Hemodynamic Therapy After Combined Valve Repair
Valvular repair and repair surgery is rapidly progressing yet rather challenging aspect of current cardiosurgical practice. Several approaches were introduced into the clinical practice to alleviate systemic inflammatory response…
- Trial name
- NCT01276444
- Testing
- Swan-Ganz catheter, transpulmonary thermodilution + central venous saturation
- Where
- Russia
- Volunteers
- 43 people
- Sponsor
- Northern State Medical University
Upper Extremity Deep Vein Thrombosis
Major Complications Related to PICC and Midline Insertion
Most important peripherally inserted central catheter (PICC) and Midline complications are thrombosis and catheter related blood stream infections.
- Trial name
- PICC/MIDLINE (NCT02489721)
- Testing
- PICC and Midline
- Where
- Italy
- Volunteers
- 547 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Catheter-Related Infections
Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age
This study is a post-marketing approval requirement to assess the safety and time to Catheter-related Bloodstream Infections (CRBSI) of DefenCath in pediatric population (birth to less than 18 years of age) who are on chronic HD…
- Trial name
- NCT06714864
- Testing
- (taurolidine and heparin) catheter lock solution, Standard of Care
- Where
- 6 sites in United States
- Volunteers
- 36 people
- Sponsor
- CorMedix Therapeutics
Anxiety, Pain
Musical Intervention and Patient's Anxiety During Central Venous Catheter Insertion in the Intensive Care Unit
Intensive care unit patients who have to undergo central venous catheter insertion and are able to hear explanations and to gave consent, will be randomized to either usual care during catheter insertion or to a musical…
- Trial name
- MUSIC-CAT (NCT03398525)
- Testing
- usual care, Musical intervention
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Neoplasm, Central Venous Catheter Thrombosis
Study in Cancer Patients With Central Line Associated Clots in the Upper Extremity Treated With Rivaroxaban (Catheter 2)
Patients with cancer and an upper extremity DVT associated with a central venous catheter (CVC) will receive rivaroxaban. CVC survival will be assessed and compared to previous rates with low molecular weight heparin (LMWH) and…
- Trial name
- NCT01708850
- Testing
- Rivaroxaban
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre
Central Line Complication
CVAD-Associated Skin Impairment in Allogeneic Stem Cell Transplant Recipients: Dressing vs No-Dressing
Central venous access device (CVAD)-associated skin impairment (CASI) is a common problem in allogeneic hematopoietic stem cell transplant (HSCT) recipients.
- Trial name
- NCT03216824
- Testing
- Dressing, No-Dressing
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Pediatric Intestinal Failure
KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure
A multi-site, randomized, 2-arm open-label trial to determine if 4% Tetrasodium (EDTA) catheter lock solution is more effective than heparin lock (standard of care) in preventing central venous catheter occlusions in children…
- Trial name
- NCT05879835
- Testing
- KiteLock 4% Sterile Catheter Lock Solution, Heparin Lock Solution
- Where
- 8 sites in United States
- Volunteers
- 124 people
- Sponsor
- SterileCare Inc.
Venous Thrombosis, Neoplasms
Post-thrombotic Syndrome & Predictors of Recurrence in Catheter-related Thrombosis
The goal of the pilot study is to determine if a multicenter prospective cohort study of cancer patients with blood clots associated with catheters is feasible.
- Trial name
- NCT01999179
- Testing
- Heparin, Low-Molecular-Weight, or direct oral anticoagulants
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Medical College of Wisconsin
Central Venous Catheter, Point of Care Ultrasound (POCUS)
Central Venous Catheter Placement With Thoracic Ultrasound and Intracavity ECG Positioning
The goal of this interventional study is to assess the feasibility of two bedside techniques for confirming central venous catheter (CVC) placement and detecting complications: Intracavity ECG monitoring to confirm internal…
- Conditions
- Central Venous Catheter, Point of Care Ultrasound (POCUS), Intracavitary Electrocardiogram Guiding, Feasibility Studies
- Trial name
- CVC-TIP (NCT07291869)
- Testing
- Intracavity ECG, Thoracic point of care ultrasound
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- York Teaching Hospitals NHS Foundation Trust
Acute Pain, Anxiety
The 50:50 Nitrous Oxide vs 2% Lidocaine Challenge
The main goal of the project is to assess pain levels and patient comfort during the administration of a 50:50 Nitrous Oxide/Oxygen gas mixture, in comparison to the same parameters under the standard method used at our…
- Conditions
- Acute Pain, Anxiety, Central Venous Catheter
- Trial name
- NCT07618676
- Testing
- Nitrous Oxide-Oxygen, Lidocaine 2% Injectable Solution
- Where
- Serbia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Institute for Oncology and Radiology of Serbia
Central Line Bloodstream Infections
The Effectiveness of Silver Alginate (Algidex) Patch in the Prevention of Central Line Infections in Very Low Birth Weight Infants
The purpose of this study is to determine whether silver alginate (Algidex) patch is effective in the prevention of central line infections in very low birth weight infants.
- Trial name
- NCT00964093
- Testing
- Silver Alginate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Central Venous Catheter Thrombosis
Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical…
- Trial name
- PHOTO CAT (NCT06417541)
- Testing
- Diseased patients with an indwelling central venous catheter who is referred to autopsy, Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Thomas Kander
Cervical Cancer, Chronic Myeloproliferative Disorders
Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter
RATIONALE: The use of dalteparin may be able to prevent complications caused by the use of a catheter to supply chemotherapy to cancer patients. It is not yet known if dalteparin is effective in reducing these complications.
- Conditions
- Cervical Cancer, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00006083
- Testing
- Fragmin
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Central Line Associated Bloodstream Infections (CLABSI), Bone Marrow Transplant
Parafilm to Prevent CLABSI in Pediatric Patients Undergoing HCT
The purpose of this study is to see if applying parafilm as an external barrier on the central line in children having a bone marrow transplant helps to prevent central line associated bloodstream infection(s) and also to assess…
- Trial name
- NCT02575079
- Testing
- Parafilm
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Emory University
Atrial Fibrillation
Multi-electrode PulmonarY Vein Isolation Versus Single Tip Wide Area Catheter Ablation for Paroxysmal Atrial Fibrillation (PAF)
The MYSTIC_PAF trial investigates the differences between treatment with a single-tip catheter against a multielectrode catheter in cardiac ablation procedures in patients with paroxysmal atrial fibrillation.
- Trial name
- MYSTIC-PAF (NCT01696136)
- Testing
- Cardiac ablation for Atrial Fibrillation
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- L.V.A. Boersma