Clinical trials: Centric Occlusion
Temporomandibular Joint Disorders
Temporary Hydrostatic Splint Therapy and Its Effects on Occlusal Forces
The goal of this non-randomized controlled trial is to analyze and compare occlusal force distribution patterns using T-Scan III before and after hydrostatic splint therapy on both healthy subjects and subjects with…
- Trial name
- NCT05827263
- Testing
- T-Scan occlusal recording No. I, Usage of the hydrostatic appliance, T-Scan occlusal recording No. II
- Where
- Lithuania
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Dental Occlusion, Occlusion
Comparison of Two Different Digital Methods in Occlusal Analysis
Aim: The aim of this study is to compare the T-Scan digital occlusal analysis system and the occlusal analysis mode of the CEREC Omnicam system, which is mainly used for design/ production, using the data recorded at the centric…
- Conditions
- Dental Occlusion, Occlusion, Jaw Relationship, Centric Occlusion
- Trial name
- NCT04798729
- Testing
- Digital Occlusal Recording with T-Scan, Digital Occlusal Recording with Cerec Omnicam
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Aortic Valve Stenosis, Valsartan
Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized mulTi-cEntric Double-blind Phase II Study
Aortic stenosis (AS) is the most frequent valvular heart disease in Western countries, with increasing prevalence. Recent guidelines recommend aortic valve intervention (surgical aortic valve replacement [SAVR] or transcatheter…
- Conditions
- Aortic Valve Stenosis, Valsartan, Angiotensin Receptor Antagonists, Transcatheter Aortic Valve Replacement
- Trial name
- ARISTOTE (NCT03315832)
- Testing
- Valsartan
- Where
- France
- Sponsor
- University Hospital, Limoges
Coronary Artery Disease
Prospective multicEntric NonranDomized Registry
The purpose of this study is to evaluate the safety and efficacy of the eucaLimus Sirolimus Eluting stent system in patients with de novo coronary lesions.
- Trial name
- ExPEND (NCT02496169)
- Testing
- eucaLimus
- Volunteers
- 400 people
- Sponsor
- Eucatech AG
Sickle Cell Disease (SCD)
An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients
Sickle cell disease (SCD) is a genetic blood disorder. Crizanlizumab is indicated to reduce the frequency of vaso-occlusive crises (VOCs) in patients with SCD aged 16 years and older.
- Trial name
- NCT04662931
- Testing
- crizanlizumab
- Where
- 7 sites in India
- Volunteers
- 140 people
- Sponsor
- Novartis Pharmaceuticals
Carotid Artery Diseases, Hypothermia
Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study
Aim of the study is to determine whether endovascular systemic cooling to a target temperature of 34-35°C initiated before, and maintained during Carotid EndoArterectomy (CEA), is feasible and safe
- Conditions
- Carotid Artery Diseases, Hypothermia, Stroke, Carotid Artery Plaque
- Trial name
- NCT02629653
- Testing
- endovascular cooling (Zoll system)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- S. Andrea Hospital
Centric Relation Registration
Quantification of the Differences in the Diagnostic Relationships Between Centric Occlusion Versus Maximum Intercuspation in Adult Orthodontic Patients : A Cross-sectional Study
The aim of the study is to quantify the differences in the diagnostic relationships between Centric occlusion versus maximum intercuspation in adult orthodontic patients with Cetric relation recoded using both conventional method…
- Trial name
- NCT06220955
- Testing
- centric relation registration, maximum intercuspation registration
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Centric Occlusion - Centric Relation Discrepancy (Disorder)
Evaluation of Masseter and Anterior Temporalis Muscles Activity After Locating Centric Relation
Statement of the Problem: To create optimum maxillomandibular relationships, ease discomfort, and restore function, occlusal devices are used, therefore, these devices are of great importance in the field of prosthodontics.
- Trial name
- NCT06095856
- Testing
- Leaf Gauge, Lucia Jig, Kois Deprogrammer
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hand Injury
Retroclavicular Approach vs Infraclavicular Approach for Plexic Bloc Anesthesia of the Upper Limb
Locoregional anesthesia provides several advantages over general anesthesia in terms of postoperative pain, decreased postoperative opioid needs and reduced recovery time for patients undergoing orthopaedic surgery.
- Trial name
- NCT02913625
- Testing
- Ultrasound guided retroclavicular block, Ultrasound guided infraclavicular block
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- Université de Sherbrooke
Aortic Valve Stenosis
PremiCron Suture for Cardiac Valve Repair
The study is a voluntary study, initiated by B. Braun to collect clinical data for PremiCron® suture concerning its key indication.
- Trial name
- PremiValve (NCT04096859)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 198 people
- Sponsor
- Aesculap AG
Metastatic Breast Cancer
Patient-Centric Study to Assess the Impact of Genomic Profiling on the Treatment of Patients With Metastatic Breast Cancer in Spain
HOPE Focus is an observational study that aims at promoting research against metastatic breast cancer by means of collective research led by patients (patient-centric trial).
- Trial name
- HOPE-Focus (NCT06991946)
- Testing
- Liquid Biopsy, Archival Tumor DNA
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- SOLTI Breast Cancer Research Group
Atherosclerotic Cardiovascular Disease
Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term
ADAPTABLE is a pragmatic clinical trial in which 15,000 patients who are at high risk for ischemic events will be randomly assigned in a 1:1 ratio to receive an aspirin dose of 81 mg/day vs. 325 mg/day.
- Trial name
- ADAPTABLE (NCT02697916)
- Testing
- aspirin
- Where
- 40 sites in United States
- Volunteers
- 15,076 people
- Sponsor
- Duke University