Clinical trials: Cerebellar Stroke
Post-stroke Depression
Investigating How the RECT Impacts Brain Functional States Through the ACC-cerebellar Loop
Experiment1: Using a brain EEG-TMS combined system, researchers aim to investigate the impact of the rostral anterior cingulate cortexr (rACC)-engaging cognitive task (RECT) combined single-pulse TMS magnetic stimulation on theta…
- Trial name
- NCT06912191
- Testing
- Left cerebellar TMS stimulation combined with the RECT task, Right cerebellar TMS stimulation combined with the RECT task, Midline cerebellar TMS stimulation combined with the RECT task
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Hemispatial Neglect, Visual Neglect
Cerebellum and Neglect
The goal of this clinical trial is to learn if a non-invasive brain stimulation method called continuous theta burst stimulation (cTBS) can improve attention in adults who have hemispatial neglect after stroke.
- Conditions
- Hemispatial Neglect, Visual Neglect, Stroke
- Trial name
- NCT07580066
- Testing
- Continuous theta burst stimulation
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Luzerner Kantonsspital
Stroke
Cerebellar Stroke and Mood Disorders
Post-stroke mood disorders (PSMD), including depression, anxiety and apathy, are observed in about 30 % of stroke patients at follow-up 3 or 4 months after stroke occurrence.
- Trial name
- CERMOOD (NCT03515486)
- Testing
- Post stroke mood disorders evaluation
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Bordeaux
Post-stroke Depression
To Explore the Neural Processing Mechanism of Cerebellum Involved in Facial Expression Recognition Based on Transcranial Magnetic Stimulation
Experiment 1: Utilizing a transcranial magnetic stimulation-electroencephalography/functional near-infrared spectroscopy system, the investigators aim to determine whether transcranial magnetic stimulation of the cerebellum can…
- Trial name
- NCT06860451
- Testing
- TMS
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Aphasia, Non-fluent Aphasia
Combining tDCS and CILT in Non-fluent Aphasia
The long-term goal of this work is to determine if combining a highly intensive, task-specific behavioral language intervention with modulation of the efferent cerebellar-cortical pathway using transcranial direct current…
- Conditions
- Aphasia, Non-fluent Aphasia, Stroke, Brain Injuries
- Trial name
- NCT05561400
- Testing
- tDCS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Stroke
Multi-session Anodal Cerebellar Transcranial Direct Current Stimulation (tDCS) vs Anodal Cerebral tDCS
To investigate which one of the two cerebellar and cerebral stimulation in comparison to sham stimulation is more effective in enhancing balance and postural stability in stroke patients
- Trial name
- NCT06525129
- Testing
- Cerebellar stimulation group (CbSG), Cerebral (M1) Stimulation group (MSG)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Stroke, Transcranial Direct Current Stimulation
Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects
Upper extremity motor impairment is one of the major sequelae of stroke, resulting in limitation of activities of daily livings.
- Conditions
- Stroke, Transcranial Direct Current Stimulation, Functional Near Infrared Spectroscopy
- Trial name
- NCT04101695
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Stroke
Cerebellar Deep Brain Stimulation or VNS for Chronic Post-stroke Motor Rehabilitation
Upper-extremity impairment after stroke remains a major therapeutic challenge and a target of neuromodulation treatment efforts.In this open-label, randomized phase I trial, we applied deep brain stimulation to the cerebellar…
- Trial name
- NCT06303960
- Testing
- Bilateral Cerebellar deep brain stimulation, Unilateral Cerebellar deep brain stimulation, Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University
Cerebellar Stroke
Decompressive Craniectomy in Patients With Cerebellar Infarction
The investigators aimed to evaluate the outcome in participants up to 80 years of age with space-occupying cerebellar infarction treated with suboccipital decompressive craniectomy (SDC) compared to medical therapy alone.
- Trial name
- DEMCI (NCT05670249)
- Testing
- suboccipital decompressive craniectomy
- Volunteers
- 72 people
- Sponsor
- Ege University
Stroke, Repetitive Transcranial Magnetic Stimulation
Effect of Cerebral and Cerebellar rTMS in Stroke Patient
This study is based on the characteristics of motor learning theory and motor learning neural network to improve motor function in stroke patients.
- Conditions
- Stroke, Repetitive Transcranial Magnetic Stimulation, rTMS, Motor Recovery
- Trial name
- NCT04570774
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Stroke, Spinocerebellar Ataxia
Laryngeal Adaptation for Speech and Swallowing
This study will test laryngeal adaptation in speech and swallowing function in healthy adults, in patients with cerebral stroke, and in patients with spinocerebellar ataxia type 6.
- Conditions
- Stroke, Spinocerebellar Ataxia, Cerebral Stroke, Dysphagia
- Trial name
- NCT03770377
- Testing
- Intermittent Perturbation to Continuous Perturbation, Continuous Perturbation to Intermittent Perturbation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Stroke, Ischemic, Cerebellar Lesions
Visual-spatial and Visual-perceptual Disorders Following Cerebellar Strokes
This study aims at assessing the proportion of patients suffering from neuro-visual troubles (visual-spatial and/or visual-perceptual ), after cerebellar strokes.
- Trial name
- VISUO-CEREBRO (NCT04920461)
- Testing
- Additional MRI sequences, Neuropsychological assessment
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Stroke, Hemiparesis After Stroke
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower…
- Conditions
- Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- NIMBLE (NCT07073235)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Danderyd Hospital
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Neurologic Disorder, Stroke
Home Based Tele-exercise for People With Chronic Neurological Impairments
To assess the impact of a 12-week virtual seated physical intervention on cardiovascular health and wellness in people with chronic neurological impairments (CNI).
- Conditions
- Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- Telex (NCT04564495)
- Testing
- Seated exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Burke Medical Research Institute
Oropharyngeal Dysphagia, Stroke
The Utility of Cerebellar Transcranial Magnetic Stimulation in the Neurorehabilitation of Dysphagia After Stroke
The study is designed to explore the effectiveness of non-invasive cerebellar stimulation to enhance motor plasticity in the cortex after stroke.
- Trial name
- NCT03274947
- Testing
- Cerebellar TMS
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Stroke, Spinal Cord Injuries (Complete and Incomplete)
Exoskeleton-assisted Neurorehabilitation
Objective assesment of the feasibility of integrating the Ekso Bionics - Ekso NR device into outpatient care Objective assesment of quality of life, functionality and clinical symptomps of patients with stroke, cerebellar ataxia…
- Conditions
- Stroke, Spinal Cord Injuries (Complete and Incomplete), Cerebellar Ataxia, Spastic Paraplegia
- Trial name
- NCT07352085
- Testing
- Gait training with exoskeleton
- Where
- Hungary
- Volunteers
- 5 people
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Stroke
Effects of Upper Extremity Rehabilitation Robot and Transcranial Direct Current Stimulation Among Patients With Stroke
Effects of upper extremity rehabilitation robot and transcranial direct current stimulation on upper extremity function among subjects with tremor after stroke
- Trial name
- NCT04055597
- Testing
- Robot and tDCS on-line
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Stroke
Effects of a Neurorehabilitation Program Based on CIMT and Non-invasive Neuromodulation Through C-tDCS on the Recovery of Paretic Upper Limb Function, Quality of Life, and Therapeutic Alliance in Women From the Araucanía Region Who Suffered a Stroke (CIMT + tDCS).
General Objective To determine the effects of a neurorehabilitation program based on Constraint-Induced Movement Therapy (CIMT) and non-invasive neuromodulation through cerebellar transcranial direct current stimulation (C-tDCS)…
- Trial name
- (CIMT - tDCS) (NCT07619703)
- Testing
- tDCS
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- Universidad de La Frontera