Clinical trials: Cerebral Abnormality
Cerebral Hemorrhage, Cerebral Ischemia
Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients With Brain Diseases
The goal of this observational study is to compare the differences in the features of cerebral multifrequency EIT(cMFEIT) images between healthy subjects and patients with brain diseases and to explore the possibility of applying…
- Conditions
- Cerebral Hemorrhage, Cerebral Ischemia, Cerebral Edema, Healthy
- Trial name
- NCT05796349
- Testing
- multifrequency EIT-based for detecting intracranial abnormalities
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jieshi Ma
Cognitive Impairment, Cognitive Decline
Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)
This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders, Cognitive Symptom
- Trial name
- MoCA-Norm (NCT03246269)
- Testing
- MoCA
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Andreas Monsch
Brain Injuries, Brain Development Abnormality
Evaluating the Efficacy of SyMRI in Clinical Pediatric Populations
Synthetic MR Technologies has created a quantified imaging solution - SyMRI - to enable radiologists to acquire quantified images and always obtain the best contrast images.
- Conditions
- Brain Injuries, Brain Development Abnormality, Brain Pathology
- Trial name
- SyMRI (NCT03494855)
- Testing
- SyMRI Software
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cancer, Cardiac Anomaly
Using NPT to Evaluate Providing PPC as ELNEC-PPC WBT for Nurses
The purpose of this study is to explain the provision of palliative care at the end of life by the implementation of the ELNEC course, as WBT Program using the Normalization Process Theory, that focus attention on how complex…
- Conditions
- Cancer, Cardiac Anomaly, Cystic Fibrosis, Muscular Dystrophy
- Trial name
- ELNEC-PPC (NCT04461561)
- Testing
- end-of-life nursing education consortium-pediatric palliative care as web based-training plus usual care
- Where
- Iraq
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Altoosi University College
Cognitive Abnormality
Evaluation of a Decision-Support Tool for Blood Biomarker Testing for Alzheimer's Disease in Primary Care
The goal of the current study is to evaluate a decision-support tool intended to help primary care providers (PCPs) communicate with patients about blood biomarker testing for Alzheimer's Disease, enhancing shared-decision making…
- Trial name
- NCT07812337
- Testing
- Shared decision-making support tool
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Premature Birth, Neurodevelopmental Disorders
Childhood Outcomes of Preterm Brain Abnormalities
Prematurely born children are at higher risk of cognitive impairments and behavioral disorders than full-term children. There is growing evidence of significant volumetric and shape abnormalities in subcortical structures of…
- Conditions
- Premature Birth, Neurodevelopmental Disorders, Brain Development Abnormality, Brain Lesion
- Trial name
- NCT03410810
- Testing
- MRI, Neurodevelopmental/Neuropsychological Assessment
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Dementia, Gait Analysis
Role of Gait Analysis in Different Type of Dementia
Aim for the work is the studying of the existence and pattern of gait impairment in pre-dementia and dementia To examine the association between dual decline in gait and cognition
- Trial name
- NCT06713070
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Concussion, Brain
Diffusion Tensor Brain MRI in the Detection of Structural Abnormality of the White Substance in Concussion
Concussions in sports are a major public health problem because of their frequency, and are often underdiagnosed because of an unspecific clinical picture or sometimes masked by the concussion itself.
- Trial name
- COMMOTION (NCT06144359)
- Testing
- specific MRI Acquisition (Diffusion Tensor Imaging) at 3T
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Epilepsy, Rolandic
Association of Processing Speed Dysfunction and Brain Functional Abnormality in ECTS
Epilepsy with centrotemporal spikes (ECTS) is the most common epilepsy syndrome in children. Language impairment has been widely investigated in patients with ECTS, but little is known about the cognitive dysfunction of…
- Trial name
- NCT04954729
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Intracranial Anomalies, Ultrasound Imaging
AI-Assisted 2D Fetal Brain Ultrasound for Intracranial Anomaly Detection
Timely detection of fetal brain anomalies is critical for improving prenatal counseling and postnatal neurological outcomes. Ultrasonography is the most commonly used and effective imaging method for evaluating fetal structures…
- Conditions
- Intracranial Anomalies, Ultrasound Imaging, Artificial Intelligence
- Trial name
- ALYSSIA (NCT07261618)
- Testing
- Alyssia - AI-Assisted Diagnostic Model for Fetal Brain Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation
Evaluation Criteria, Diagnostic Criteria, Surgical Indications, and Establishment of Surgical Standards for "Cerebral Tinnitus Syndrome" Caused by Internal Jugular Vein Stenosis.
"Cerebral Tinnitus," also known as "cranial tinnitus," refers to the patient-reported perception of intracranial sounds. It often presents as "Cerebral Tinnitus Syndrome," which includes symptoms such as tinnitus with hearing…
- Conditions
- Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation, Nerosurgery, Assessment, Self
- Trial name
- NCT07560280
- Testing
- Atlas Transverse Process Mastoidectomy with Lysis and Perfusion
- Where
- China
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Fetal Anomaly, Brain Malformation
Artificial Intelligence Algorithm for the Screening of Abnormal Fetal Brain Findings at First Trimester Ultrasound Scan
Visualization of the posterior fossa brain spaces, their spatial relationship and measurements can be obtained in the midsagittal view of fetal head, the same used for NT measurement (9), and plays an important role in the early…
- Trial name
- AIRFRAME (NCT05790473)
- Testing
- Artificial Intelligence
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fetal Anomalies, Brain Malformation
AIRFRAME: Artificial Intelligence for Recognition of Fetal bRain AnoMaliEs at Second Trimester Fetal Brain Scan
Obstetric ultrasound represents the standard of care for the screening of the fetal anomalies. However, its performance is dependent upon several parameters including type of anomaly, gestational age, maternal habitus and skills…
- Trial name
- AIRFRAME (NCT06675266)
- Testing
- Development of AI algorithm for early detection of fetal brain anomalies in the second trimester screening scan
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Schizophrenia, Social Cognition
Social Dysfunction and Brain Dysfunction in Patients With Schizophrenia
There were a few studies about the relationship of structural or functional abnormalities of brain and social cognitive dysfunctions in patients with schizophrenia.
- Trial name
- NCT01903915
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Abnormality in Fetal Heart Rate or Rhythm, Ultrasound
Uterine, Fetal Cerebral Doppler and Oligohydramnios to Predict Abnormal Heart Rate Tracings in Postterm Pregnancies
Objective: To estimate the value of uterine, fetal cerebral Doppler and oligohydramnios to predict abnormal fetal heart rate tracings in pregnancies at or beyond 41 weeks
- Conditions
- Abnormality in Fetal Heart Rate or Rhythm, Ultrasound, Late Pregnancy
- Trial name
- NCT03703037
- Testing
- Ultrasound and Doppler ultrasound
- Where
- Mexico
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez