Clinical trials: Cerebral Disorder
Alzheimer Disease, Dementia
Assistive Technology and Reduced Caregiver Burden
The study investigated a six-week randomized controlled trial study in a small cohort of 16 family caregivers of individuals living with Alzheimer's disease and related dementias.
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burden, Quality of Life
- Trial name
- ck (NCT05352529)
- Testing
- The MapHabit system, Dementia educational videos
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- MapHabit, Inc.
Cerebrovascular Accident
To Determine the Therapeutic Effect of the Music Glove and Conventional Hand Exercises to Subacute Stroke Patients
The investigators are trying to determine the therapeutic effect of the music glove and conventional hand exercise program to the subacute stroke patients. All participants will be randomized into two groups: AB and BA.
- Trial name
- NCT02410629
- Testing
- Music Glove, Conventional Hand Exercise Program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- David Reinkensmeyer
Stroke
Closed-loop Sensorimotor Integrated (CSMI) Control in Exoneuromusculoskeleton (ENMS) for Precise Wrist-hand Rehabilitation After Stroke
The goal of this randomized controlled trial is to determine whether using both brain and muscle signals to control a wrist-hand rehabilitation robot can improve recovery in people with chronic stroke.
- Trial name
- NCT07737431
- Testing
- CSMI-Controlled ENMS, EMG-Driven ENMS
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- The Hong Kong Polytechnic University
Alzheimer Disease, Mild Cognitive Impairment
Evaluating the Efficacy of Artificial Intelligence-based Computer Aided Diagnosis Software That Assists in Determining Whether or Not to Conduct Amyloid PET for the Diagnosis of Alzheimer's Disease by Predicting Amyloid PET Positivity in Mild Cognitive Impairment Patients
Purpose of clinical trial; This clinical trial is designed to evaluate the effectiveness of 'NeuroAI' prediction accuracy compared to the amyloid PET test results by retrospectively collecting medical data of patients with mild…
- Trial name
- NCT05383053
- Testing
- NeuroAI
- Where
- South Korea
- Volunteers
- 227 people
- Sponsor
- Neurozen Inc.
Adult Day Programs, Continuing Care
Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family/friend Caregivers
This study seeks to understand the effects of adult day programs on older adults, especially those with dementia, and their caregivers.
- Conditions
- Adult Day Programs, Continuing Care, Old Age; Dementia, Family/Friend Caregivers
- Trial name
- NCT06496945
- Testing
- Adult day program use, Other community care (non-attendees)
- Where
- 4 sites in Canada
- Volunteers
- 3,000 people
- Sponsor
- York University
Acute Stroke Patients Requiring Invasive Mechanical Ventilation
Stroke Prognosis in Intensive CarE
The S.P.I.C.E registry is an investigator-initiated prospective multicenter cohort study which will be conducted in 35 ICUS in the Paris area.The aim of the study is to determine the trajectory of acute stroke patients requiring…
- Trial name
- SPICE (NCT03335995)
- Where
- France
- Volunteers
- 364 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Encephalitis, Tick-Borne
Study of the Safety, Tolerability and Immune Response of TBE Vaccines Administered to Healthy Children
The purpose of this study is to evaluate the safety, immunogenicity and tolerability of TBE vaccines administered to children.
- Trial name
- NCT00311441
- Testing
- Tick-Borne Encephalitis vaccine
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Novartis
Stroke, Disability Physical
Adaptation and Validation of the LUNS for Use in Turkey.
According to the most up-to-date knowledge, there is no Turkish comprehensive and validated instrument to assess stroke survivors' unmet needs in the longer term.
- Conditions
- Stroke, Disability Physical, Quality of Life
- Trial name
- NCT06278805
- Testing
- The reliability and validity study of the T-LUNS
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Uşak University
Migrainous Headache
Treatment of Acute Migraine Headache in Children
Migraine is common in children and is one of the most common etiologies of headache leading to emergency room presentation in children.
- Trial name
- NCT00355394
- Testing
- Metoclopramide
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Children's Hospital of Philadelphia
Alzheimer Disease
Drug-Drug Interaction to Study the Effect of BMS-708163 on Pharmacokinetics (PK) of Galantamine Extended Release (ER)
The purpose of the study is to find out if the plasma concentration of galantamine extended release is changed when BMS-708163 is administered at the same time.
- Trial name
- NCT01039194
- Testing
- galantamine, BMS-708163
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Bristol-Myers Squibb
Prebiotics, Anxiety
Gut-brain Axis, Brain Function, and Behaviour.
The aim is to test if dietary supplementation with prebiotics reduces measures of anxiety in healthy human participants with high self-reported levels of anxiety.
- Conditions
- Prebiotics, Anxiety, Humans, Magnetic Resonance Imaging
- Trial name
- NCT03554694
- Testing
- Prebiotics
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Bacterial Infections, Bone Diseases, Infectious
Fosfomycin I.v. for Treatment of Severely Infected Patients
The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin…
- Conditions
- Bacterial Infections, Bone Diseases, Infectious, Osteomyelitis, Central Nervous System Bacterial Infections
- Trial name
- FORTRESS (NCT02979951)
- Where
- 50 sites in Austria, Germany and 3 more
- Volunteers
- 1,000 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Upper Motor Neuron Disease
Efficiency of Spatially Distributed Sequential Stimulation (Sdss) for Functional Electrical Stimulation (FES) of Upper Motor Neuron Syndrome (UMR) Patients
To determine whether Spatially Distributed Sequential Functional Electrical Stimulation is more effective than Standard Electrical Stimulation During Functional Electrical Stimulation in Upper Motor Neuron Patients
- Trial name
- SDSS_UMS (NCT06421753)
- Testing
- SDSS, Standard Electrical Stimulation During Functional Electrical Stimulation
- Where
- France
- Volunteers
- 10 people
- Sponsor
- UGECAM Rhône-Alpes
Acromegaly
Efficacy and Safety of Octreotide Capsules (MYCAPSSA) in Acromegaly
Octreotide capsule is a novel, orally-administered formulation of the commercially-available injectable drug octreotide. In a recent phase 3 trial, oral octreotide capsules demonstrated maintenance of biochemical response up to…
- Trial name
- OPTIMAL (NCT03252353)
- Testing
- octreotide capsules
- Where
- 60 sites in United States, Australia and 15 more
- Volunteers
- 56 people
- Sponsor
- Chiasma, Inc.
West Nile Fever
An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) Disease
Although the serious form of West Nile Virus (WNV) disease, referred to as neuroinvasive disease, is rare, it can result in permanent disabilities and occasionally death.
- Trial name
- NCT00091845
- Testing
- AVI-4020 Injection
- Volunteers
- 50 people
- Sponsor
- Sarepta Therapeutics, Inc.
Epilepsy
Radiosurgery or Open Surgery for Epilepsy Trial
This study will compare radiosurgery (focused radiation, Gamma Knife Radiosurgery) with temporal lobectomy (standard surgical care) as a treatment of temporal lobe epilepsy.
- Trial name
- ROSE (NCT00860145)
- Testing
- radiosurgery, temporal lobectomy
- Where
- 14 sites in United States, India
- Volunteers
- 61 people
- Sponsor
- University of California, San Francisco
Stroke
Treadmill Training With Functional Electric Stimulation After Stroke
The purpose of this study was to investigate the effects of the treadmill training with functional electric stimulation on sensorimotor cortical reorganization and functional improvement in subjects with chronic stroke.
- Trial name
- NCT02812472
- Testing
- Treadmill training with functional electrical stimulation, Treadmill training without functional electrical stimulation
- Volunteers
- 18 people
- Sponsor
- National Yang Ming Chiao Tung University
Equine Encephalitis
Vaccination Trial of a Recombinant MVA-BN-WEV Vaccine in Healthy Adult Subjects
To assess safety and tolerability as well as immune responses to the MVA-BN-WEV vaccine in the 3 treatment groups receiving different doses.
- Trial name
- NCT04131595
- Testing
- MVA-BN-WEV Dose 1, MVA-BN-WEV Dose 2, MVA-BN-WEV Dose 3
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bavarian Nordic
Trigeminal Neuralgia, Headache Disorders
Trigeminal Ganglion RFT vs Maxillary/Mandibular PRF in the Treatment of Trigeminal Neuralgia
Trigeminal ganglion (TG) radiofrequency thermocoagulation (RFT) and ultrasound (US)-guided maxillary or mandibular (max/mand) pulsed radiofrequency (PRF) are two interventional procedures for the treatment of trigeminal neuralgia…
- Trial name
- NCT06366139
- Testing
- Radiofrequency thermocoagulation of the trigeminal ganglion, Maxillary/Mandibular nerve pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Diskapi Teaching and Research Hospital
Anxiety
Do Mind Ease Interventions Reduce Feelings of Acute Anxiety? A Randomised Controlled Trial
This study investigates the short-term effects of the MindEase app on anxiety levels.
- Trial name
- NCT05850975
- Testing
- intervention with this name in MindEase app, reading about anxiety
- Where
- United Kingdom
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- University of Oxford
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