Clinical trials: Cerebral Infarct
Cardiovascular Diseases, Myocardial Infarction
Real World Evidence Study of Statin Use in Brazil
A cross-sectional real-world data study designed to assess the use of statins in individuals assisted within the primary care system in Brazil.
- Conditions
- Cardiovascular Diseases, Myocardial Infarction, Stroke, Hypertension
- Trial name
- RWE-Statins (NCT05285085)
- Testing
- Statin
- Where
- Brazil
- Volunteers
- 2,133,900 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Stroke, Cerebral Infarction
Study of NeuroAid In Enhancing Recovery After Stroke
TIERS is a phase II to generate detailed preliminary data on the efficacy of NeuroAid in post-stroke recovery, and to assess the utility of the rehabilitation outcome measure instruments used.
- Trial name
- TIERS (NCT00721825)
- Testing
- Neuroaid
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Moleac Pte Ltd.
Stroke, Cerebrovascular Accident
Fluoxetine Opens Window to Improve Motor Recovery After Stroke
The FLOW trial is a randomized placebo-controlled trial analyzing the effect of coupling an anti-depressant, fluoxetine (Prozac), and exercise to improve motor recovery following a stroke.
- Conditions
- Stroke, Cerebrovascular Accident, Cerebral Infarction, Brain Infarction
- Trial name
- FLOW (NCT03448159)
- Testing
- Fluoxetine Hydrochloride, Exercise Program
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Infarction, Anterior Cerebral Artery
Effect of Rosuvastatin on Prognosis of Clinical Response in Acute Ischemic Stroke Patients(REPAIRS)
This study is randomized, open-lable, parallel-group and comparator-controlled. 456 consecutive patients with acute ischemic stroke admitted within the first 72 hours after onset of symptoms will be studied.
- Trial name
- REPAIRS (NCT02484027)
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Stroke
Impact of Verticalization on Intracranial Hemodynamics Assessed in Transcranial Doppler at the Acute Phase of Cerebral Infarction
The management of patients with ischemic stroke or transient ischemic attack is based on the preservation of a brain area by maintaining sufficient intracranial hemodynamics (IH) and with rapid recanalization.
- Trial name
- STAND (NCT03985059)
- Testing
- Transcranial Doppler
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cardiovascular Diseases, Cerebrovascular Accident
Health Professionals Follow-up Study
To test the hypothesis that increased risk of coronary heart disease, stroke, peripheral vascular disease, and cancer is related to diets high in saturated fat, animal protein, and hydrogenated vegetable oil, and low in…
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Peripheral Vascular Diseases
- Trial name
- NCT00005182
- Volunteers
- 50,000 people
- Sponsor
- Harvard School of Public Health (HSPH)
Carotid Stenosis, Coronary Artery Disease
Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients
Prospective, single-center, clinical registry of patients with symptomatic/critical carotid artery stenosis at risk of stroke coexisting with unstable or multivessel severe coronary artery disease and/or severe valvular heart…
- Conditions
- Carotid Stenosis, Coronary Artery Disease, Valvular Heart Disease, Myocardial Infarction
- Trial name
- SIM-GUARD (NCT04973579)
- Testing
- Simutaneous (single anaesthesia) carotid artery stenting with MicroNet covered stent (CGuard) and cardiac surgery (CABG or surgical valve replacement / repair procedure)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- John Paul II Hospital, Krakow
Aortic Stenosis
Femoral vs Radial Approach and MRI Evaluation of Strokes
Symptomatic cerebral infarction following cardiac catheterization is rare but silent brain injury could occur at an unexpectedly high rate.
- Trial name
- NCT00329979
- Testing
- vascular access site
- Where
- France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Caen
Cerebrovascular Accident, Paralysis
Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy
The purpose of this study is to determine if giving amphetamines along with standard rehabilitation speeds motor recovery after a stroke.
- Trial name
- NCT00001783
- Testing
- 0-15 Water
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Aortic Valve Stenosis
INTERvention With Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation (INTERCEPTavi)
The study aims to evaluate the processes of a pilot single-centre randomised controlled trial (RCT) of carbon-dioxide flushing of transcatheter aortic valves (TAVI-CO2) versus standard saline flushing of valves (TAVI-S) and…
- Conditions
- Stroke, Aortic Valve Stenosis, Silent Cerebral Infarct, Vascular Brain Injury
- Trial name
- INTERCEPTavi (NCT05146037)
- Testing
- CO2 and saline flushing, Saline flushing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Imperial College London
CADASIL
The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage?
The Cerebral Amyloid angiopathy (CAA) is the leading cause of cortical hemorrhage after 65 years. The presence of cerebral infarction is also reported anatomically in the AAC. MRI studies of these infarcts are rare.
- Trial name
- CAA (NCT02837354)
- Testing
- No intervention
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Infarction, Middle Cerebral Artery, Ischemic Stroke,
Implantation of Olfactory Ensheathing Cells (OECs)
Recruited patients should receive the endoscopic surgery for picking the olfactory mucosa 1 to 2 months before transplantation. The Olfactory Ensheathing Cells (OECs) will be cultured and expanded under the rule of GTP.
- Conditions
- Infarction, Middle Cerebral Artery, Ischemic Stroke,, Stroke With Hemiparesis,, Thromboembolic Stroke.
- Trial name
- OECs (NCT01327768)
- Testing
- Olfactory ensheathing cells
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- China Medical University Hospital
Carotid Atherosclerosis, Myocardial Infarction
Comparison of Asymptomatic Carotid Atherosclerosis Between Frequent and Infrequent Blood Donors
Iron has been proposed to contribute to atherogenesis in humans by facilitating the oxidation of lipoproteins. This observational study will evaluate the association between frequency of blood donation - expected to be associated…
- Trial name
- NCT00001589
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cerebral Herniation
Hemicraniectomy in Patients With Malign Middle Cerebral Artery Infarction
This trial is a prospective, randomized, controlled, clinical trial based on a stroke center. We randomly assigned 151 patients 41 years of age or older (median, 65 years; range, 41 to 83) with malignant middle cerebral artery…
- Trial name
- NCT04555460
- Testing
- Hemicraniectomy, Conservative medical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Ege University
Carotid Artery Disease, Carotid Stenosis
Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study)
To collect clinical outcome and device performance data on the FDA 510(k)-cleared Emboshield® BareWire™ Rapid Exchange Embolic Protection System and FDA-approved Xact® Rapid Exchange Carotid Stent System when used under…
- Conditions
- Carotid Artery Disease, Carotid Stenosis, Stroke, Atherosclerosis
- Trial name
- NCT00287508
- Testing
- Carotid artery stenting with filter (interventional)
- Volunteers
- 1,500 people
- Sponsor
- Abbott Medical Devices
Stroke, Cerebral Infarction
Enhancing Physical Therapy Best Practice for Improving Walking After Stroke
The aim of this study is to assess the effect of implementing best practices into current stroke rehabilitation physical therapy on walking outcomes.
- Conditions
- Stroke, Cerebral Infarction, Brain Ischemia, Infarction, Brain
- Trial name
- NCT04238260
- Testing
- Enhancing Physical Therapy Usual Care, Physical Therapy Usual Care
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- University of British Columbia
Cadasil
CERebrolysin In CADASIL
The objective of this trial is the global risk-benefit assessment of Cerebrolysin as compared to Placebo in patients with genetically proven CADASIL.
- Trial name
- CERICA (NCT05755997)
- Testing
- Cerebrolysin, 0.9 % NaCl
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Ever Neuro Pharma GmbH
Subcortical Aphasia, Ischemic Stroke
Language Functional Reorganization in Subcortical Infarction Patients
Post stroke aphasia (PSA) is one of the most frequently happened deficiency of stoke, affecting speaking,comprehension, writing and reading of language.
- Trial name
- NCT03668132
- Testing
- ischemic brain damage
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Acute Ischemic Stroke
Methylprednisolone With Endovascular Thrombectomy for Large Ischemic Stroke
It is uncertain whether intravenous methylprednisolone improves outcomes for acute anterior circulation large vascular occlusion (LVO) patients with a large infarct core.
- Trial name
- MATCH (NCT06870448)
- Testing
- Methyprednisolone sodium succinate
- Where
- China
- Volunteers
- 1,614 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Delirium, Cerebral Infarction
the Incidence and the Association Between Motor Subtypes and Outcome of Delirium in Ischemic Stroke Patients
this study examines the incidence of newly developed delirium in patients who admit to university hospital stroke unit for cerebral infarction, and analyze the association between delirium motor subtypes and short-term outcome in…
- Trial name
- NCT03317106
- Where
- South Korea
- Volunteers
- 943 people
- Sponsor
- Chungnam National University Hospital
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