Clinical trials: Cerebral Infarct
Acute Ischemic Stroke
Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study)
Lacunar infarction is an ischemic stroke occurred by small perforating artery occlusion . Twenty percent of ischemic stroke is lacunar infarction.
- Trial name
- NCT04839224
- Testing
- carbogen, phenylephrine
- Where
- South Korea
- Volunteers
- 3 people
- Sponsor
- Yonsei University
Myocardial Infarction, Stroke
Testing a Community Intervention to Increase Aspirin Use
This research will test the effect of mass media or mass media plus a clinic based education program will improve appropriate aspirin use for cardiovascular disease prevention.
- Trial name
- NCT02607917
- Testing
- Mass Media plus clinic intervention., Media
- Where
- United States
- Volunteers
- 10,800 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke, Sleep Apnea Syndromes
The Impact of Ergonomic Circadian Light on Hospitalized Stroke Patients in a Rehabilitation Unit
The purpose of this study is to investigate the impact of exposure to ergonomic circadian light on physiological and mental parameters in stroke patients admitted for rehabilitation.
- Conditions
- Stroke, Sleep Apnea Syndromes, Depression, Anxiety
- Trial name
- NCT02186392
- Testing
- Circadian Light luminaries
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Acute Myocardial Infarction, Restenoses, Coronary
Abbott Vascular Medical Device Registry
The AV-MDR is a prospective, non-randomized, open-label, multi-center registry. The purpose of the AV-MDR study is to proactively collect and evaluate clinical data on the usage of the devices in scope within their intended use…
- Conditions
- Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
- Trial name
- AV-MDR (NCT04573660)
- Testing
- Coronary and peripheral stents, Pacing catheters, Vascular plugs
- Where
- 37 sites in United States, Australia and 12 more
- Volunteers
- 3,784 people
- Sponsor
- Abbott Medical Devices
Stroke, Cerebral Infarction
Enhancing Physical Therapy Best Practice for Improving Walking After Stroke
The aim of this study is to assess the effect of implementing best practices into current stroke rehabilitation physical therapy on walking outcomes.
- Conditions
- Stroke, Cerebral Infarction, Brain Ischemia, Infarction, Brain
- Trial name
- NCT04238260
- Testing
- Enhancing Physical Therapy Usual Care, Physical Therapy Usual Care
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- University of British Columbia
Cardiovascular Diseases, Heart Diseases
Salt Sensitivity, Cardiovascular and Metabolic Disease
To identify the role of salt-sensitivity of blood pressure in the pathogenesis of hypertension.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Angina Pectoris
- Trial name
- NCT00005489
- Sponsor
- Indiana University
Intracranial Hemorrhages, Acute Ischemic Stroke
AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction
- Trial name
- AI-REACT (NCT06018545)
- Testing
- Ground truthing, Reading
- Where
- 4 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Stroke, Diabetes Mellitus
Neurological Complications at Stroke Patients With Diabetes Mellitus
It is to be investigated if a correlation exist between the development of the HbA1c value and the complication rate is following a stroke.
- Trial name
- SDM (NCT01172977)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Evangelisches Krankenhaus Bielefeld gGmbH
Cerebrovascular Stroke, Intracranial Hemorrhages
Predictive Value of Infarction Volume on Hemorrhagic Transformation in Ischemic Stroke/TIA With Non-valve Atrial Fibrillation(NVAF) Patients Using Rivaroxaban
This study was aimed at patients with newly diagnosed stroke / TIA associated with nonvalvular atrial fibrillation. We will observe the effect of early using rivaroxaban anticoagulation on hemorrhagic transformation, and explore…
- Conditions
- Cerebrovascular Stroke, Intracranial Hemorrhages, Anticoagulant, Matrix Metalloproteinases
- Trial name
- NCT03772457
- Testing
- Rivaroxaban
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Ischemic Heart Disease
Door-to-door Survey of Cardiovascular Health, Stroke and Ischemic Heart Disease in Atahualpa
The aim of the Atahualpa project is to evaluate the cardiovascular (CVH) status of the inhabitants of a rural village of coastal Ecuador as well as to determine the prevalence and retrospective incidence of stroke and ischemic…
- Trial name
- TAP (NCT01627600)
- Where
- 2 sites in Ecuador
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Hospital Clínica Kennedy
Acute Ischemic Stroke
Study of Aspirin and TPA in Acute Ischemic Stroke
This study will determine the safety of 500mg of aspirin added to IV TPA at standard doses to prevent re-occlusion of cerebral vessels after successful reperfusion.
- Trial name
- NCT00417898
- Testing
- Aspirin
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Cerebral Infarction
Comparison of Triflusal and Clopidogrel in Secondary Prevention of Stroke Based on the Genotyping
The purpose of this study is to compare the preventive effect of stroke between triflusal and clopidogrel in ischemic stroke patient based on the cytochrome P450 2C19 (CYP2C19) polymorphism.
- Trial name
- MAESTRO (NCT01174693)
- Testing
- Triflusal, Clopidogrel
- Where
- 18 sites in South Korea
- Volunteers
- 795 people
- Sponsor
- Gangnam Severance Hospital
Cardiovascular Disease and Lipoprotein(a)
Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD
This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)
- Trial name
- Lp(a)HORIZON (NCT04023552)
- Testing
- TQJ230
- Where
- 902 sites in United States, Argentina and 41 more
- Volunteers
- 8,323 people
- Sponsor
- Novartis Pharmaceuticals
Cerebrovascular Accident, Hypercholesterolemia
Vasomotor Reactivity In Cerebral Small Vessel Disease And New Approach To Treat Lacunar Stroke
The main purpose of this study is to evaluate the efficacy of atorvastatin treatment during 3 months (80mg/day) on cerebral vasoreactivity (CVR) in lacunar patients.
- Trial name
- LA BICHAT (NCT00163150)
- Testing
- Atorvastatin
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Subarachnoid Hemorrhage
Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage
The investigators will test the central hypothesis that DFO treatment after SAH may improve cerebrovascular regulation, mitigate ischemic neural injury, and serve as an effective neuroprotectant against delayed ischemic injury…
- Trial name
- NCT02216513
- Testing
- desferrioxamine (DFO)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Ischemic Stroke
Rescues On Reperfusion Damage In Cerebral Infarction by Nelonemdaz
Efficacy and safety of Neu2000, a multi-target drug designed to prevent both NMDA receptor-mediated excitotoxicity and free radical toxicity, will be investigated in acute ischemic stroke patients receiving endovascular treatment…
- Trial name
- RODIN (NCT05041010)
- Testing
- Neu2000KWL group
- Where
- 24 sites in South Korea
- Volunteers
- 496 people
- Sponsor
- GNT Pharma
Osteoarthritis Pain, Myocardial Infarction (MI)
Community Physical Exercise Program in Chronic Disease
This study focuses on promoting physical activity (PA) through the implementation of a Community Physical Exercise Program for Chronic Diseases (CPEP-CD), targeting individuals aged 50 years and older with at least two of the…
- Conditions
- Osteoarthritis Pain, Myocardial Infarction (MI), Hypertension, Dyslipidemia
- Trial name
- CPEPCD (NCT06771024)
- Testing
- Physical Exercise
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv
Subarachnoid Hemorrhage, Aneurysmal, Cerebral Injury
Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage
An investigator-initiated clinical drug study Main Objective: To explore neuroprotective properties of xenon in patients after aneurysmal subarachnoid hemorrhage (SAH).
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Cerebral Injury, Cerebral Ischemia, Cerebral Infarction
- Trial name
- Xe-SAH (NCT04696523)
- Testing
- Xenon, air/oxygen
- Where
- 7 sites in Finland, Sweden
- Volunteers
- 160 people
- Sponsor
- Turku University Hospital
Aneurysmal Subarachnoid Hemorrhage, Cerebral Ischemia
Perfusion Imaging Score to Predict Delayed Cerebral Ischemia
Aneurysmal subarachnoid hemorrhage (aSAH) is a significant public health concern, annually affecting over 30,000 Americans and ranking among the leading causes of stroke-related life-years lost in individuals aged 65 and younger.
- Trial name
- NCT07030985
- Testing
- CTP scan, Neurological and neuropsychological testing
- Volunteers
- 55 people
- Sponsor
- Stanford University
TIA, Stroke
Evaluation of the HARM for the Detection of a Cerebral Ischemia in TIA/TNA Patients
The research project investigates the incidence of the hyperintense acute reperfusion marker (HARM) in patients with transient ischemic attack (TIA) or transient neurological attack (TNA).
- Conditions
- TIA, Stroke, Ischemia, Diagnoses Disease
- Trial name
- NCT03555643
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsmedizin Mannheim
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