Clinical trials: Cerebral Infarction
Cerebral Infarction
The Efficacy and Safety Study of ALbumin Therapy in Acute Ischemic Stroke
In this clinical study, the efficacy and safety of ALbumin is to be evaluated for the patients occurred within 12 hours of acute ischemic stroke.
- Trial name
- ALbumin (NCT01684462)
- Testing
- Human Serum Albumin 20, 0.9 % Normal Saline
- Where
- 4 sites in South Korea
- Volunteers
- 2 people
- Sponsor
- Seoul St. Mary's Hospital
Heart Ischemia, Cerebral Ischemia
Organ Protection by Remote Ischemic Preconditioning for Surgical Treatment of Pediatric Congenital Heart Disease
Cardiac surgery is associated with risk of perioperative inflammation and ischemia leading to cerebral and myocardial morbidity and mortality.
- Trial name
- RIPHeart (NCT01312623)
- Testing
- Remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- University Hospital Schleswig-Holstein
Aneurysmal Subarachnoid Hemorrhage
Cilostazol and Nimodipine Combined Therapy After Aneurysmal Subarachnoid Hemorrhage (aSAH)
The investigators seek to demonstrate that the combined use of cilostazol and nimodipine will significantly decrease the rate of delayed cerebral infarction and cerebral vasospasm after cerebrovascular intervention when compared…
- Trial name
- NCT04148105
- Testing
- Cilostazol 100 MG
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Henry Ford Health System
Venous Thromboembolism (VTE), Acute Myocardial Infarction With ST Segment Elevation
Heat Shock Protein 47 in Thrombosis
The goal of this observational study is to learn if the novel biomarker Heat shock protein 47 (HSP47) can be used as a prognostic marker for vascular disease in people with acute venous thromboembolism (VTE), myocardial…
- Conditions
- Venous Thromboembolism (VTE), Acute Myocardial Infarction With ST Segment Elevation, Stroke (in Patients With Atrial Fibrillation)
- Trial name
- NCT06731673
- Where
- 2 sites in Denmark, Germany
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cardiovascular Diseases, Heart Diseases
Stroke and MI in Users of Estrogen/Progestogen
To estimate the relative risks of acute myocardial infarction (MI) and of stroke in postmenopausal users of estrogen/progestogen (E/P) combinations and to estimate the relative risks of MI and of stroke in users of estrogen alone.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00005466
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Middle Cerebral Artery Stroke
The Efficacy and Safety of MK0724 IV for Improvement of Neurological Damage and Recovery From Middle Cerebral Artery Ischemic Stroke (0724-018)
The safety and efficacy of MK0724 will be assessed in patients with acute middle cerebral artery stroke using the Action Reach Arm Test (ARAT).
- Trial name
- NCT00401310
- Testing
- Comparator: MK0724
- Volunteers
- 150 people
- Sponsor
- Merck Sharp & Dohme LLC
Aortic Stenosis
Femoral vs Radial Approach and MRI Evaluation of Strokes
Symptomatic cerebral infarction following cardiac catheterization is rare but silent brain injury could occur at an unexpectedly high rate.
- Trial name
- NCT00329979
- Testing
- vascular access site
- Where
- France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Caen
Cryptogenic Embolic Stroke, Active Cancer
Identification the Cause of Cerebral Infarction in Patients With Cancer
Although there has been increasing interest in the association between cancer and cerebrovascular disease, the underlying pathophysiology of stroke in cancer patients is still not fully understood.
- Trial name
- NCT02212496
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Samsung Medical Center
Stroke, Cardiovascular
Effects of Thermal Stimulation on Motor Recovery and Neuromuscular Property of Lower Extremity in Stroke
This 3-year study will recruit a total of 72 subjects with first-ever stroke after 3 months onset from the department of Physical Medicine and Rehabilitation in 3 teaching hospitals.
- Trial name
- NCT04306120
- Testing
- Traditional Rehabilitation Therapy
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Cardiovascular Diseases, Heart Diseases
Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events
To explore the role of insulin growth factor in cardiovascular disease in older men and women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00086424
- Volunteers
- 5,888 people
- Sponsor
- Albert Einstein College of Medicine
Myocardial Infarction, Death
Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit
It is recognized that endothelial dysfunction is a major factor contributing to the atherogenic process. Abnormal function of the endothelium is detectable prior to obvious intimal lesions in patients with risk factors for…
- Conditions
- Myocardial Infarction, Death, Cerebrovascular Accident, Congestive Heart Failure
- Trial name
- NCT01618123
- Where
- 2 sites in United States, Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Cerebral Stroke
Hyperbaric Oxygen Therapy After Stroke - PILOT
The goal of this pilot study is to establish more information about hyperbaric oxygen therapy for this group of patients, and give us more information of how to initiate the best possible main study.
- Trial name
- NCT04149379
- Testing
- Hyperbaric oxygen
- Where
- Norway
- Sponsor
- Norwegian Underwater Intervention (NUI)
Brain Infarction
Cortical Cerebellar Infarctions Associated With Patent Foramen Ovale in Young Stroke Patients
The investigator retrospectively analyzed consecutive young (<60 years) cryptogenic stroke patients with Patient Foramen Ovale (PFO) recruited between January 2016 and May 2019 in our center, and compared these patients with sex…
- Trial name
- NCT04043559
- Testing
- MRI scanner, Contrast transoesophageal echocardiography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Coronary Heart Disease, Stroke
The Copenhagen City Heart Study
The Copenhagen City Heart Study is an ongoing cardiovascular population study initiated in 1976 which has examined approximately 25,000 individuals from the general population.
- Conditions
- Coronary Heart Disease, Stroke, Heart Failure, Cancer
- Trial name
- CCHS (NCT02993172)
- Volunteers
- 23,891 people
- Sponsor
- Bispebjerg Hospital
Acute Ischemic Stroke, Arterial Thrombosis
Intra-arterial Thrombolysis After Successful Thrombectomy for Acute Ischemic Stroke in the Posterior Circulation (IAT-TOP)
The CHOICE study suggested that the use of adjunct intra-arterial alteplase after successful endovascular reperfusion in large vessel occlusion acute ischemic strokes may result in a greater likelihood of excellent neurological…
- Conditions
- Acute Ischemic Stroke, Arterial Thrombosis, Posterior Circulation Brain Infarction
- Trial name
- NCT05897554
- Testing
- intra-arterial alteplase
- Where
- China
- Volunteers
- 247 people
- Sponsor
- Xuanwu Hospital, Beijing
Aphasia, Stroke
Melodic-Intonation-Therapy and Speech-Repetition-Therapy for Patients With Non-fluent Aphasia
We are doing this clinical trial in order to evaluate two different treatments for non-fluent aphasia: Melodic Intonation Therapy (MIT) and Speech Repetition Therapy (SRT).
- Conditions
- Aphasia, Stroke, Cerebrovascular Accident, Apoplexy
- Trial name
- NCT00903266
- Testing
- Melodic Intonation Therapy, Speech-Repetition-Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Beth Israel Deaconess Medical Center
Ischemic Stroke, Remote Ischaemic Preconditioning
Effect of Remote Ischemic Preconditioning on Early Neurological Deterioration in Acute Perforating Artery Infarction
This study aims to conduct a prospective, randomized, double-blind, multicenter, parallel-controlled, group-sequential trialto scientifically evaluate the safety and efficacy of remote ischemic preconditioning (RIC) in preventing…
- Trial name
- RIC-END (NCT07237542)
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 910 people
- Sponsor
- Jinling Hospital, China
Hyperlipidemia, Hypercholesterolemia
Patient and Provider Assessment of Lipid Management Registry
The purpose of the Patient and Provider Assessment of Lipid Management Registry (PALM) is to gain a better understanding of physicians' cholesterol medication prescribing practices, patient and physician attitudes and beliefs…
- Conditions
- Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes
- Trial name
- PALM (NCT02341664)
- Where
- 14 sites in United States
- Volunteers
- 7,658 people
- Sponsor
- Duke University
Brain Ischemia, Cerebral Ischemia
PROgnostic Value of MicroParticles and Markers of Hemostasis in TIA and Ischemic Stroke
The purpose is to investigate if different microparticles and markers of hemostasis predict outcome after TIA or ischemic stroke and to study the association between these variables and stroke subtype or etiology.
- Conditions
- Brain Ischemia, Cerebral Ischemia, Extracellular Vesicles, Hemostasis
- Trial name
- PROMPTS (NCT05524506)
- Where
- Sweden
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Unruptured Intracranial Aneurysm, Infarction Cerebral
Chronic Remote Ischemic Conditioning in Small Infarctions Associated with Stent-assisted Coiling of Unruptured Intracranial Aneurysms
1. Disease Description Stent-assisted coiling has become an effective treatment modality for intracranial aneurysms. With continuous advancements in periprocedural antiplatelet regimens, the incidence of symptomatic…
- Trial name
- CRISIS (NCT06826144)
- Testing
- remote ischemic conditioning
- Volunteers
- 84 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University