Clinical trials: Cerebral Palsy Children
Cerebral Palsy, Prosthesis User
Use of Low Cost Prostheses to Improve Upper Extremity Function in Children With Cerebral Palsy
The purpose of the study is to assess the effectiveness of an upper extremity prosthesis in improving the upper extremity function of children with cerebral palsy who have limited use of their hands.
- Trial name
- NCT03122171
- Testing
- Occupational Therapy Treatment
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Cerebral Palsy
Investigating the Effect of Stochastic Resonance Vibration on Gait and Balance and Upper Extremity Function in Children With Cerebral Palsy
The purpose of this research study is to determine the effects of wearable vibration devices for children with cerebral palsy and impaired arm function.
- Trial name
- NCT04388787
- Testing
- Stochastic resonance (SR) wraps
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Commonwealth University
Cerebral Palsy, Physical Activity
Effects of Hippotherapy on Physical Fitness and Attention in Cerebral Palsy
This research analyzes whether hippotherapy improves the physical activity, cardiopulmonary fitness, and attention in children with cerebral palsy and whether this enhances their general health and quality of life.
- Conditions
- Cerebral Palsy, Physical Activity, Attention Disorder
- Trial name
- NCT03870893
- Testing
- hippotherapy
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Samsung Medical Center
Chronic Troublesome Sialorrhea, Cerebral Palsy
Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability
The objective of this study is to investigate the efficacy and safety of NT 201 compared with placebo for the treatment of chronic troublesome sialorrhea associated with neurological disorders (e.g.
- Conditions
- Chronic Troublesome Sialorrhea, Cerebral Palsy, Stroke, Traumatic Brain Injury
- Trial name
- SIPEXI (NCT02270736)
- Testing
- NT 201
- Where
- 31 sites in Georgia, Hungary and 4 more
- Volunteers
- 256 people
- Sponsor
- Merz Pharmaceuticals GmbH
Cerebral Palsy
The Effects of Neurodevelopmental Therapy on Feeding and Swallowing.
Our study is planned to investigate the effects of neck and trunk stabilization exercises, which are structured from Neurodevelopmental therapy method-Bobath concept (NDT-B) principles, on feeding and swallowing activity in…
- Trial name
- NCT04403113
- Testing
- Structured neck and trunk stabilization exercises, Feeding and oral motor intervention strategies, Caregiver training related to feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cerebral Palsy, Muscle Spasticity
Dysport® Pediatric Lower Limb Spasticity Study
The purpose of this research study is to determine whether Dysport® is effective in the treatment of increased stiffness of the calf muscles and to evaluate the safety of this treatment in children with Cerebral Palsy.
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Trial name
- NCT01249417
- Testing
- Botulinum toxin type A
- Where
- 29 sites in United States, Chile and 4 more
- Volunteers
- 241 people
- Sponsor
- Ipsen
Cerebral Palsy, Hemiplegia
Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy
A randomized control trial of bimanual training. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement therapy in children with…
- Conditions
- Cerebral Palsy, Hemiplegia, Children, Pediatric
- Trial name
- NCT00305006
- Testing
- Constraint-Induced Movement Therapy (CIMT), Hand-Arm Bimanual Intensive Therapy (HABIT)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Teachers College, Columbia University
Cerebral Palsy, Hemiplegia
Immersive Virtual Reality for Visuo-motor Integration Skill Assessment
A significant deficit affecting nearly half of children with hemiplegia is visual-motor integration, or eye-hand coordination. Children have difficulties integrating visual and motor information to effectively plan and execute…
- Trial name
- NCT04612049
- Testing
- Immersive virtual reality visuo-motor skill assessment
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northeastern University
To Determine Efficacy of the Headpod, Cerebral Palsy
Measuring Head Control Change With 2D Video Analysis After Utilization of Headpod in Children With Poor Head Control
Inclusion Criteria: children ages 2 to 14 years with poor head control and non progressive diagnoses. Exclusion criteria: significant change of status i.e. prolonged hospitalization, surgery; inability to tolerate using Headpod.
- Trial name
- headpod (NCT02764775)
- Testing
- Headpod
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Texas Woman's University
Osteoporosis, Cerebral Palsy
Prevention of Post Operative Bone Loss in Children
Hypothesis: one-dose pamidronate will prevent post-operative bone loss in children at risk for low bone density Plan: children with chronic disease such as CP, spina bifida, etc.
- Conditions
- Osteoporosis, Cerebral Palsy, Spina Bifida, Osteopenia
- Trial name
- NCT00655681
- Testing
- pamidronate, saline
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of New Mexico
Mitochondrial Diseases
A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease
A long-term extension study to assess the safety, tolerability and efficacy of cysteamine bitartrate delayed-release capsules (RP103) in children with inherited mitochondrial diseases who previously enrolled into study…
- Trial name
- NCT02473445
- Testing
- Cysteamine Bitartrate
- Where
- 5 sites in United States
- Volunteers
- 22 people
- Sponsor
- Amgen
Cerebral Palsy, Exercise Therapy
RCT on Interactive Computer Play on Trunk Control in CP
Objectives: This proposal is to investigate the effect of a 6-week training programme using an Interactive computer play (ICP) on the trunk control, balance and gross motor function in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy, Exercise Therapy, Postural Balance
- Trial name
- NCT02975804
- Testing
- Tymo
- Where
- Hong Kong
- Volunteers
- 18 people
- Sponsor
- The Hong Kong Polytechnic University
Cerebral Palsy (CP)
Pediatric Teleneuromodulation
This study will explore using remotely monitored 'active' non-invasive brain stimulation in children with cerebral palsy. Participants will receive active non-invasive brain stimulation with synchronous safety monitoring and…
- Trial name
- NCT05071586
- Testing
- Soterix 1x1 tDCS LTE Stimulator Device Model 1401
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
Cerebral Palsy
Stand-on Ride-on Power Mobility Devices for Children With Cerebral Palsy
The goal of this interventional study is to learn about the biomechanical factors underlying the beneficial changes in children with cerebral palsy after using individually-adapted stand-on ride-on power mobility devices (PMD).
- Trial name
- NCT06455930
- Testing
- Stand-on ride-on power mobility device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Florida
Cerebral Palsy
Effect of Trunk Stabilization Exercises on Quality of Life and Communication in Cerebral Palsy
To investigate the effectiveness of neck and trunk stabilization exercises on communication and quality of life (QoL) in children with cerebral palsy (CP) with oral motor problems.
- Trial name
- NCT04214080
- Testing
- Neurodevelopmental treatment (NDT), Feeding and oral-motor intervention strategies, Neck and trunk stabilization exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Cerebral Palsy
Validity of Bispectral Index Monitoring During Deep Sedation
During Intramuscular botulinum toxin injections for children with cerebral palsy, immobility is essential to inject botulinum toxin to the right muscle.
- Trial name
- NCT02096549
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yeungnam University College of Medicine
Cerebral Palsy, Neuromuscular Scoliosis
Seating System for Scoliosis in Non-ambulatory Children With Cerebral Palsy: A Pilot Randomized Controlled Trial
The effect of a modular seating system on coronal and sagittal balance of the spine and pelvic obliquity in children with non-ambulatory (Gross Motor Function Classification System Level IV-V) and scoliosis The hypothesis in our…
- Trial name
- NCT03862625
- Testing
- a modular adaptive seating system, home exercise program for scoliosis
- Volunteers
- 30 people
- Sponsor
- Merve Damla Korkmaz
Inherited Mitochondrial Disease, Including Leigh Syndrome
Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease
To evaluate safety, tolerability and efficacy of cysteamine bitartrate delayed-release capsules (RP103) administered at a target maintenance dose of 1.3 g/m²/day in two divided doses, every 12 hours, for up to 6 months in…
- Trial name
- MITO-001 (NCT02023866)
- Testing
- Cysteamine Bitartrate
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Amgen
Transition-age Youth, Developmental Disabilities
Evaluation of Project TEAM (Teens Making Environmental and Activity Modifications)
The purpose of this study is to determine the extent to which Project TEAM (Teens making Environment and Activity Modifications) is an effective, socially valid, and feasible intervention that prepares youth with developmental…
- Conditions
- Transition-age Youth, Developmental Disabilities, Cerebral Palsy, Autism
- Trial name
- ProjectTEAM (NCT02714868)
- Testing
- Project TEAM, Matched Comparison
- Volunteers
- 82 people
- Sponsor
- Boston University Charles River Campus
Cerebral Palsy, Hemiplegic Cerebral Palsy
Dynamic Gait Index in Hemiplegic Cerebral Palsy
The purpose of this study is to assess validity and reliability of Dynamic Gait Index (DGI) in patients with unilateral spastic cerebral palsy
- Conditions
- Cerebral Palsy, Hemiplegic Cerebral Palsy, Gait Disorders, Neurologic
- Trial name
- NCT03662139
- Testing
- Dynamic Gait Index
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University