Clinical trials: Cerebral Saturation
Hypoplastic Left Heart, Surgery
NIRS in Neonatal Cardiac Surgery
Due to the small size of infants and the use of bypass machines, physicians have difficulty assessing whether the infant's brain and body is getting enough oxygen during heart surgery.
- Trial name
- NCT00166101
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Regional Cerebral Tissue Oxygen Saturation
Effect of Dexmedetomidine and Propofol on Regional Cerebral Tissue Oxygen Saturation
50 patients divided into 2 groups .Group I Dexmedetomidine infusion. Group II with Propofol infusion
- Trial name
- NCT03817112
- Testing
- Dexmedetomidine Hydrochloride 0.1 MG/ML, Propofol 10 MG/ML
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Rotator Cuff Tear Arthropathy
Vasopressin to Prevent Hypotension During Beach Chair Surgery
Patients undergoing surgery in beach chair position (BCP) are at risk for cerebral ischaemia. The impacts of arginine vasopressin (AVP) on haemodynamics and cerebral oxygenation are evaluated during surgery in BCP.
- Trial name
- NCT01687894
- Testing
- Vasopressins, propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Chonnam National University Hospital
Obstructive Sleep Apnea
Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea
The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea are not clarified. We hypothesize that patients with obstructive sleep apnea have an abnormal level of some vasoactive hormones…
- Trial name
- NCT00438412
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Preterm Infant, Brain Injuries
Cerebral Regional Tissue Oxygen Saturation to Guide Oxygen Delivery in Preterm Neonates During Immediate Transition
The aim of the COSGOD Phase III trial is to examine, if it is possible to increase survival without cerebral injury in preterm neonates <32 weeks of gestation by monitoring the cerebral tissue oxygen saturation in addition to…
- Conditions
- Preterm Infant, Brain Injuries, Birth Hypoxia
- Trial name
- COSGOD (NCT03166722)
- Testing
- Control group, Study group
- Where
- 12 sites in Austria, Canada and 5 more
- Volunteers
- 655 people
- Sponsor
- Medical University of Graz
Surgery
The Effects of Anesthetic Method on Cerebral Oxygen Saturation in Geriatric Patients Undergoing Transurethral Surgery
The effects of anesthetic method on cerebral oxygen saturation in geriatric patients undergoing transurethral surgery.
- Trial name
- NCT01147146
- Testing
- propofol, fentanyl, atracurium, bupivacaine, bupivacaine, Midazolam
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Cerebral Tumor, Stroke
Magnetic Resonance Imaging Evaluation of the Tissular Oxygen Saturation in Brain
The purpose of this study is to measure the tissular oxygen saturation in brain by magnetic resonance imaging on subjects and to correlate the results with near infrared spectroscopy measurements.
- Trial name
- GADOXY (NCT02317055)
- Testing
- imaging
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Intraoperative Infusion, Lidocaine
Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries
This study aims to compare the effect of intraoperative infusion of either lidocaine or dexmedetomidine on the incidence of postoperative delirium (POD) in elderly patients undergoing major surgeries.
- Conditions
- Intraoperative Infusion, Lidocaine, Dexmedetomidine, Cerebral Oxygen Saturation
- Trial name
- NCT07108764
- Testing
- Lidocaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Anesthesia
Mannitol Improves Cerebral Oxygen Saturation
Decreased cerebral oxygen saturation (rSO2) was reported to occur during insufflation for laparoscopic procedures due to increased Intracranial pressure (ICP) with resultant decrease in cerebral perfusion pressure.
- Trial name
- NCT02091180
- Testing
- Mannitol, Control
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Regional Cerebral Oxygen Saturation
Regional Cerebral Oxygen Saturation Under General Anesthesia A Pilot Study
A total of 60 patients will be enrolled in the study: 20 each who receive surgery in beach chair position or Trendelenburg's position and 20 patients undergoing cardiac surgery.
- Trial name
- NCT02101242
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Charite University, Berlin, Germany
Apnea+Hypopnea, Tracheal Dilatation
Tracheal Dilatation in Pediatric Patients With Acquired Tracheal Stenosis, and the Effects of Apneic Oxygenation
The study presents an alternative method of tracheal dilatation in pediatric patients with acquired tracheal stenosis. Dilatation is performed by the use of balloon catheter connected with manometer, that is bronchoscopic guided…
- Conditions
- Apnea+Hypopnea, Tracheal Dilatation, Igel, Tracheal Stenosis
- Trial name
- NCT05028023
- Testing
- Apneic oxygenation - supplemental high flow oxygen administration by an apneic way
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- Aristotle University Of Thessaloniki
Alzheimer Disease, Sleep Apnea, Obstructive
The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients
The purpose of this study is to determine the effects of the anticholinesterase drug donepezil on sleep in Alzheimer disease patients. Sleep structure and respiratory parameters will be analyzed by polysomnography.
- Trial name
- ACHALZSLEEP (NCT00480870)
- Testing
- donepezil
- Where
- Brazil
- Volunteers
- 65 people
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Hypoxia, Hypotension
Vasopressors for Cerebral Oxygenation
Liberal fluid administration is one of risk factors of developing acute lung injury (ALI) in thoracic surgery. Therefore, the investigators try to restrain fluid administration, and in the case of intraoperative hypotension, the…
- Trial name
- NCT02009007
- Testing
- dopamine, phenylephrine
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Cerebral Ischemia
Hypercapnia During Shoulder Arthroscopy
The purpose of this study is to evaluate the effects of hypercapnia on hemodynamics and cerebral oxygenation during shoulder arthroscopy.
- Trial name
- NCT02643030
- Testing
- hypercapnia, normocapnia
- Volunteers
- 40 people
- Sponsor
- Gachon University Gil Medical Center
Cerebral Oxygen Saturation, Postoperative Cognitive Function
Effect of Cerebral Oxygen Saturation Monitoring on POCD of Elderly Patients Undergoing Shoulder Arthroscopy
To observe whether adjusting the level of intraoperative controlled hypotension through cerebral oxygen saturation monitoring can improve postoperative cognitive function(POCD) and reduce postoperative neurological complications…
- Trial name
- NCT05615480
- Testing
- Controlled hypotension guided by cerebral oxygen saturation monitoring
- Volunteers
- 400 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Laparoscopic Nephrectomy, Cerebral Oxygen Saturation
Pneumoperitoneum and Cerebral Oxygenation
In this study, the changes in cerebral oxygen saturation due to low and high pressure pneumoperitoneum implementation were measured in patients who underwent laparoscopic nephrectomy.
- Trial name
- NCT04671121
- Testing
- Standart pressure pneumoperitoneum, Low pressure pneumoperitoneum
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ondokuz Mayıs University
Carotid Endarterectomy, Cerebral Autoregulation
Association Between Local Cerebral Oxygenation Monitoring and Postoperative Stroke in Carotid Endarterectomy
Carotid endarterectomy (CEA) is used to treat symptomatic extracranial internal carotid artery stenosis. The occult stroke of CEA patients evaluated by magnetic resonance imaging 3 days after operation was as high as 17%.
- Trial name
- NCT06406842
- Testing
- Cerebral oxygenation index guided hemodynamics management
- Where
- 2 sites in China
- Volunteers
- 560 people
- Sponsor
- Beijing Tiantan Hospital
Glioma, Brain Metastases
Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI
Standard Magnetic Resonance Imaging (MRI) is based on the excitation of hydrogen nuclei that are presents in water molecules, which abundance in human body allows for obtention of superior contrast.
- Trial name
- GlioCEST (NCT05464992)
- Testing
- Additional CEST sequences during PET/MRI exam
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Paul Strauss
Hyperextension Injury of Neck
Effects of Cervical Hyperextension on Cervical Blood Flow, Cerebral Oximetry and Cognitive Functions.
The goal of this observational study is to determine the effects of cervical hyperextension on cerebral oximetry and cognitive functions in healthy individuals without other additional factors such as anesthesia and surgical…
- Trial name
- NCT05576857
- Testing
- Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Duzce University
Surgical Complications From General Anesthesia, Hypertension
Monitoring Hypertensive Patients's Cerebral Oxygen Saturation
The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.
- Conditions
- Surgical Complications From General Anesthesia, Hypertension, Cerebral Ischemia, Cerebral Anoxia
- Trial name
- MHPCOS (NCT02147275)
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Huazhong University of Science and Technology