Clinical trials: Cerebral Saturation
Acupuncture, Postoperative Delirium (POD)
Study of Acupuncture on Postoperative Delirium in Patients With Diabetes Mellitus
1. To evaluate the effectiveness and safety of acupuncture on POD in diabetic patients undergoing surgery, to provide effective prevention and treatment measures of integrated traditional Chinese and western medicine for reducing…
- Conditions
- Acupuncture, Postoperative Delirium (POD), Diabetes Mellitus
- Trial name
- NCT05535985
- Testing
- acupuncture
- Volunteers
- 215 people
- Sponsor
- Lingling Ding
Children
The Effect of Position Change on Pain and Cerebral Oxygen Saturation
This study is a randomized controlled experimental study to investigate the effect of position change on pain and cerebral oxygen saturation after endotracheal aspiration in pediatric patients.
- Trial name
- NCT06622330
- Testing
- Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Medipol University Hospital
Healthy
Validation of Brain Oxygenation Monitor
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- NCT00815490
- Testing
- Desaturation
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
NIRS and Anesthesiology
NIRS and Anesthesiology
Our aim in this study is to investigate the effects of the positions applied in Intracranial Surgery on Cerebral Oxygenation(with NIRS device) and to evaluate the superiority of the patient positions used to each other.
- Trial name
- NCT05978310
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Trakya University
SSNHL(Sudden Sensory Neural Hearing Loss)
The Effect of Oxygen Administration on Regional Cerebral Oxygen Saturation (rSO2) in the Non-block Side After Stellate Ganglion Block
Stellate ganglion block (SGB) is known to increase blood flow to the innervation area of the stellate ganglion. Near infrared spectroscopy reflects changes of blood volume and allows continuous, non-invasive, and bedside…
- Trial name
- NCT01532713
- Testing
- oxygen administration
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yonsei University
TBI (Traumatic Brain Injury), Acute Brain Injuries
Study of Cerebral Tissue Oxygenation During Transfusion in Traumatic Brain Injury
This proposal aims to provide some objective, non-invasively achieved, physiologically relevant data in order to provide some rational basis for decision-making for transfusion in sTBI.
- Trial name
- NIRSTBI (NCT01728831)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Postoperative Delirium, Cerebral Oxygen Saturation
Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation
This study compares the effects of ibuprofen administered during surgery and within the first 24 hours after surgery, versus no ibuprofen, on cerebral oxygenation, postoperative changes in consciousness (postoperative delirium…
- Conditions
- Postoperative Delirium, Cerebral Oxygen Saturation, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- NCT07399184
- Testing
- ibuprofen
- Volunteers
- 54 people
- Sponsor
- Ondokuz Mayıs University
Healthy
Nonin 4 Wavelength Cerebral Oximeter Study
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- Nonin4 (NCT01762722)
- Testing
- Reduction of inspired oxygen
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duke University
Anesthesia, Cerebral Blood Flow
Hypertension and Cerebrovascular Hemodynamics in General Anaesthesia
During anesthesia, blood pressure-raising medications are often required to achieve an adequate blood pressure level. However, there is limited knowledge about what constitutes an adequate blood pressure to ensure sufficient…
- Conditions
- Anesthesia, Cerebral Blood Flow, Regional Cerebral Oxygen Saturation, Blood Pressure
- Trial name
- NCT06855407
- Testing
- Blood pressure elevation
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Umeå University
Prematurity of Fetus, Patent Ductus Arteriosus
Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants
The purpose of this study is to examine the influence medical or surgical treatment for patent ductus arteriosus in preterm infants on cerebral and renal tissue oxygenation and on cardiac output.
- Trial name
- NCT01428180
- Testing
- Indomethacin, Surgical Ligation, Ibuprofen
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- University of Ulm
Congenital Heart Defect, Single-ventricle
NIRS in Congenital Heart Defects - Correlation With Echocardiography
Neonatal patients with congenital heart defects (CHD) have changing physiology in the context of transitional period. Patients with CHD are at risk of low perfusion status or abnormal pulmonary blood flow.
- Conditions
- Congenital Heart Defect, Single-ventricle, Coarctation of Aorta, Atrioventricular Canal
- Trial name
- NCT04106479
- Testing
- NIRS evaluation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Neonates and Preterm Infants, Infant Respiratory Distress Syndrome
Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 Minutes
Respiratory distress syndrome (RDS) is common in very preterm infants due to surfactant deficiency. Surfactant replacement therapy is lifesaving, and current guidelines recommend the less invasive surfactant administration (LISA)…
- Conditions
- Neonates and Preterm Infants, Infant Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal, Surfactant
- Trial name
- SurfStab I (NCT07261787)
- Testing
- Poractant alfa (Curosurf®) - 1-minute administration, Poractant alfa (Curosurf®) - 5-minute administration
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Medical University of Graz
Disorder of Hip Joint
Cerebral Oximetry and Anesthetic Technique
The purpose of the study is to compare the effects of spinal and general anesthesia on transcranial regional cerebral oxygen saturation in geriatric patients undergoing total hip arthroplasty.
- Trial name
- NCT03349658
- Testing
- general anesthesia, spinal anesthesia
- Volunteers
- 82 people
- Sponsor
- Antalya Training and Research Hospital
Cardiac Arrest
Evaluation of the Quality of Cardio-Pulmonary Resuscitation (CPR) in Cardiac Arrest Patients
The prognosis of cardiac arrest patients is generally poor. Recent studies have showed that the high quality of CPR increases the survival after cardiac arrest.
- Trial name
- NCT00951704
- Where
- 2 sites in Finland
- Volunteers
- 1,000 people
- Sponsor
- Tampere University Hospital
Critical Illness, Sepsis
Cerebral Oxygen Challenge of Passive Leg Raising Test in Sepsis
Sepsis related cerebral dysfunction was underestimated in critical illness setting, and inflammatory response of brain could not be monitored directly and cerebral oximetry offered information of cerebral dysfunction.
- Conditions
- Critical Illness, Sepsis, Cerebral Injury
- Trial name
- NCT03523169
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Patients Undergoing Cardiac Surgery
The Relation Between Preoperative ScO2 and the Postoperative Course of Humoral Organ Dysfunction Markers.
Cerebral oxygen saturation (ScO2) is a measure of cerebral and systemic oxygen delivery to demand ratio. An observational trial in a heterogeneous cohort of 1078 patients patients revealed that a ScO2 below 50% absolute during…
- Trial name
- NCT01409941
- Volunteers
- 765 people
- Sponsor
- University of Luebeck
Colorectal Cancer
Study to Evaluate Oxygen Monitoring at Different Stages of Neuromuscular Blockade in Colorectal Surgery
Anesthesia favouring deep/intense neuromuscular blockade during laparoscopy may restore hemodynamics. However, no studies has been performed comparing oxygenation parameters during laparoscopy in colorectal surgery in either…
- Trial name
- OXYMUBLOC (NCT02327494)
- Testing
- neuromuscular blockade
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Universitari de Bellvitge
Ventilation Mode, Pleth Variability Index
Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Objective: This study was designed to evaluate the accuracy of Pleth Variability Index (PVI), Perfusion Index (PI) and Regional Oxygen Saturation (rSO2) in both ventilation modes in patients undergoing septorhinoplasty operation…
- Conditions
- Ventilation Mode, Pleth Variability Index, Perfusion Index, Regional Cerebral Oxygen Saturation
- Trial name
- NCT06407362
- Testing
- Cerebral Oxygen Saturation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Spinal Anesthesia-Induced Hypotension, Cerebral Oxygenation
Effects of Ondansetron Timing During Spinal Anesthesia for Urologic Surgery
This study will evaluate whether the timing of intravenous ondansetron administration affects cerebral oxygenation and hemodynamic stability in older adults undergoing endoscopic urologic surgery under spinal anesthesia.
- Trial name
- NCT07858149
- Testing
- Ondansetron 8 mg, 0.9 % sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Istanbul University
Thoracic Surgery, Epidural Anesthesia
The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery
Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation.
- Conditions
- Thoracic Surgery, Epidural Anesthesia, Cerebral Oxygen Saturation
- Trial name
- NCT04373174
- Testing
- Regional oximetry probe, Thoracic Epidural block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital