Clinical trials: Cerebrovascular Apoplexy
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Stroke
Effect of a Community Exercise Programme on Stroke Patients
Physical activity is known to be beneficial for supporting health and wellbeing. A number of schemes and strategies have been developed to improve uptake of physical activity in the United Kingdom (UK) population, including the…
- Trial name
- NCT05320549
- Testing
- Community Programme
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Winchester
Stroke
Navigation Brain Stimulation for Evaluation of the Neuroprotective Drug Efficiency in Patients After Ischemic Stroke.
Ischemic stroke (IS) causes high mortality and severe disability. To improve outcome it's very important to choose the right way of the management of the patient and an appropriate drugs.
- Trial name
- 3C (NCT01388738)
- Testing
- citicoline, L-Alpha glycerylphosphorylcholine, cerebrolysin
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Clinical Institute of the Brain, Russia
Oropharyngeal Dysphagia, Stroke
Effect of a Cooling Sensation Flavor on the Swallow Response in Post-stroke Patients With Oropharyngeal Dysphagia
Current oropharyngeal dysphagia (OD) treatment in older patients is based on compensatory strategies (fluid thickening and texture modified diets) that improve swallow safety but do not improve the swallowing function.
- Conditions
- Oropharyngeal Dysphagia, Stroke, Swallowing Disorder
- Trial name
- NCT06250426
- Testing
- Pre-thickened oral nutritional supplement with a cooling sensation flavour, Pre-thickened oral nutritional supplement without a cooling sensation flavour
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital de Mataró
Stroke, Stroke, Acute
Phase 1 Study to Assess AER-271
The objective of this Phase 1 trial is to assess the safety, tolerability and pharmacokinetics of AER-271 in health subjects.
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- NCT03804476
- Testing
- AER-271
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aeromics, Inc.
Stroke, Atherosclerosis
Comparison of the Improvement and Safety of the Ankle Brachial Arterial Pressure Index of Sarpogrelate and Clopidogrel in Stroke Patients With Decreased Ankle Brachial Arterial Pressure Index and Intermittent Claudication of Lower Limb Vascular Atherosclerosis.
The clinical trial aims to confirm the improvement effect of the ankle brachial index and the safety of sarpogrelate administration compared to clopidogrel in stroke patients with decreased ankle brachial arterial pressure index…
- Trial name
- NCT06424548
- Testing
- Administration of Sarpogrelate, Traditional administration of Clopidogrel
- Volunteers
- 100 people
- Sponsor
- Ewha Womans University Seoul Hospital
Stroke
Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke
Ischemic stroke has a variety of treatments and currently drug therapy is one of the main treatments.A number of clinical studies have proved that alprostadil (PGE1) has pharmacological effects of significant dilation of blood…
- Trial name
- NCT03252626
- Testing
- Alprostadil, Normal saline
- Volunteers
- 950 people
- Sponsor
- The First Hospital of Jilin University
Atrial Fibrillation
Atrial Fibrillation (AF) Clinic to Improve the Treatment of Patients With Atrial Fibrillation.
Randomized controlled trial comparing specialized AF Clinic with 'care as usual' Hypothesis: treatment of AF patients in the AF-Clinic by a nurse, specialised in AF, using guideline-based dedicated software, under supervision of…
- Trial name
- AFClinic (NCT00753259)
- Testing
- AF Clinic, Care as Usual
- Where
- 2 sites in Netherlands
- Volunteers
- 712 people
- Sponsor
- Maastricht University Medical Center
D000784, D020521
CARbon Dioxide Flooding to Reduce Postoperative Neurological Injury Following Surgery for Acute Type A Aortic Dissection
Aortic dissection is a life-threatening condition and a consequence of a tear of the innermost of the three aortic layers- the intima.
- Trial name
- CARTA (NCT04962646)
- Testing
- Carbon dioxide flooding
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Skane
Neurogenic Dysphagia
Effect of Mendelsohn Maneuver, Effortful Swallow Training, and the Shaker Exercise on Swallowing Ability Among Dysphagic Patients With Cerebrovascular Accident
The study aims to Compare the effect of Mendelsohn maneuver, effortful swallow training, and the Shaker exercise on neurogenic dysphagia among stroke patients.
- Trial name
- NCT07271888
- Testing
- Compare the effect of Mendelsohn maneuver, effortful swallow training, and the Shaker exercise on neurogenic dysphagia among stroke patients.
- Volunteers
- 104 people
- Sponsor
- University of Baghdad
Traumatic Brain Injury, Stroke
Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury
Background: Previous research has shown that certain parts of the brain are involved in voluntarily stopping an ongoing motor response (movement); however, it is not known whether this same network is also involved in suppressing…
- Conditions
- Traumatic Brain Injury, Stroke, Headache, PTSD
- Trial name
- NCT01194661
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sleep Disorder, Stroke
Sleep Disorders in Transient Ischemic Attack and Stroke: SOMN'AIC Study
Sleep disorders in the setting of stroke are numerous, including sleep-related breathing disorders, insomnia, excessive daytime sleepiness and restless legs syndrome.
- Trial name
- SOMN'AIC (NCT03274505)
- Testing
- Questionnaires
- Where
- 3 sites in France
- Volunteers
- 153 people
- Sponsor
- Hospices Civils de Lyon
Ischemic Stroke
Rescues On Reperfusion Damage In Cerebral Infarction by Nelonemdaz
Efficacy and safety of Neu2000, a multi-target drug designed to prevent both NMDA receptor-mediated excitotoxicity and free radical toxicity, will be investigated in acute ischemic stroke patients receiving endovascular treatment…
- Trial name
- RODIN (NCT05041010)
- Testing
- Neu2000KWL group
- Where
- 24 sites in South Korea
- Volunteers
- 496 people
- Sponsor
- GNT Pharma
Stroke, Ischemic, Stroke Hemorrhagic
Evaluation of the Effectiveness and Safety of Keeogo™ Dermoskeleton in Subjects With Mobility Impairments Due to Stroke
A multi-site, interventional, non-comparative, single-arm trial to evaluate the safety of the Keeogo™ Dermoskeleton in subjects with hemiparesis due to ischemic or hemorrhagic stroke.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Hemiparesis
- Trial name
- NCT03986320
- Testing
- Keeogo™ Dermoskeleton
- Where
- 4 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- B-Temia, Inc.
Cerebral Hemiplegia
Falls-based Training for Walking Post-Stroke
We propose a study that uses challenging walking exercises as a research training program and compare balance and walking abilities against a non-challenging exercise program, in a group of 40 people with long standing (> 6…
- Trial name
- FBT (NCT02787759)
- Testing
- Hands-Free Walking, Challenge Based plus Hands-Free'
- Volunteers
- 54 people
- Sponsor
- University of Alabama at Birmingham
Stroke, Ischemic
Rehabilitation Program Dedicated to Post-stroke Lateropulsion Including Exoskeleton Assisted Exercises
Lateropulsion is a deficit in the body orientation with respect to the vertical in the coronal plane, defined by the presence of one of the three signs: lateral body tilt, active pushing from the sound limbs, and resistance to…
- Trial name
- EXOLAT (NCT07023770)
- Testing
- specific lateropulsion rehabilitation program (exoskeleton + specific physiotherapy orientation rehabilitation), Conventional physiotherapy without without exercises dedicated to lateropulsion or verticality representation alleviation
- Where
- 2 sites in France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Grenoble
Stroke
A Preliminary Feasibility Efficacy of Participation in Daily Life Promotion Program
Efficacy of Participation in Daily Life Promotion Program for Patients with Chronic Stroke
- Trial name
- NCT02802956
- Testing
- Daily Life Promotion Program, general rehabilitation treatment
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Stroke, Rehabilitation
Effectiveness of Mindfulness-based Cognitive Therapy Undergoing Post Stroke Rehabilitation
The goal of this clinical trial is to investigate the efficacy of mindfulness-based cognitive therapy compared to usual care for stroke survivors undergoing inpatient rehabilitation.
- Conditions
- Stroke, Rehabilitation, Mindfulness
- Trial name
- NCT05844722
- Testing
- Mindfulness-based intervention therapy, usual care
- Where
- Hungary
- Volunteers
- 93 people
- Sponsor
- National Institute for Medical Rehabilitation, Hungary
Visual Field Defect, Peripheral, Stroke
Improving Visual Field Deficits With Noninvasive Brain Stimulation
This is a randomized, pilot interventional study in participants with visual field deficit (VFD) caused by cortical lesion. Damage to the primary visual cortex (V1) causes a contra-lesional, homonymous loss of conscious vision…
- Conditions
- Visual Field Defect, Peripheral, Stroke, Visual Impairment, Hemianopsia
- Trial name
- NCT05085210
- Testing
- transcranial random noise stimulation (tRNS), Computer Based Visual Training, Virtual Reality Based Visual Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Stroke, Aphasia
Dual Site-dual Channel Non-invasive Brain Stimulation for Language and Cognitive Function in Stroke Patients
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in post stroke patients.
- Conditions
- Stroke, Aphasia, Cognitive Impairment
- Trial name
- NCT03486782
- Testing
- IFG stimulation, DLPFC stimulation, aphasia therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
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