Clinical trials: Cerebrovascular Diseases
Fabry Disease
Podocyturia - Predictor of Renal Dysfunction in Fabry Nephropathy
In patients with Fabry disease, this research study explores the presence of podocytes in their urine as a potential non-invasive biomarker for baseline kidney disease; and explores changes in the quantity of podocytes in their…
- Trial name
- NCT02994303
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Washington
Ischemic Stroke, Stroke
Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke
The primary goal of this trial is to determine if individuals with acute ischemic stroke treated with a medium dose of IV rt-PA plus IV eptifibatide started within 3 hours of symptom onset are more likely to have a better outcome…
- Conditions
- Ischemic Stroke, Stroke, Brain Infarction
- Trial name
- CLEAR-ER (NCT00894803)
- Testing
- Eptifibatide, rt-PA
- Where
- 20 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of Cincinnati
Spasticity, Stroke
Efficacy and Cost-effectiveness of Spasticity Treatment With Multifocal TENS
Spasticity is a common consequence of injury to the central nervous system and can be a major problem in motor function and everyday activities.
- Conditions
- Spasticity, Stroke, Cerebral Palsy
- Trial name
- NCT02261142
- Testing
- Multifocal TENS garment (Mollii®)
- Volunteers
- 31 people
- Sponsor
- Linkoeping University
Stroke, Cerebrovascular Accident
Enhancing Plasticity in Stroke Patients With Severe Motor Deficit
This study will evaluate the effectiveness of sustained peripheral nerve stimulation coupled with functional motor training, to improve hand motor function in poorly recovered stroke patients.
- Trial name
- NCT02633215
- Testing
- S88 Dual Output Stimulator by Grass Technologies
- Volunteers
- 36 people
- Sponsor
- Lumy Sawaki
Cerebrovascular Disease
Application of QDSA Platform in Cerebrovascular Diseases
Cerebrovascular diseases pose a major global public health challenge, characterized by exceptionally high mortality and disability rates, with their pathogenesis closely linked to hemodynamic abnormalities.
- Trial name
- RADAR (NCT06902415)
- Testing
- QDSA (Quantitative Digital Subtraction Angiography)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tiantan Hospital
STROKE
The Immediate Effect of Electrical Stimulation Transcranial Direct Current (tDCS) Associated With the Use of FES, in Muscle Activity of the Tibialis Anterior Muscle, Balance and Plantar Pressure Distribution of Individuals With Hemiparesis Due to Stroke
Background: Transcranial direct current stimulation (tDCS) is currently considered a beneficial method for patients with neurological problems due to the modulation of cortex activity as well as the enhancement and prolongation…
- Trial name
- NCT02389608
- Testing
- Transcranial direct current stimulation (tDCS), Functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Stroke
Predictors for Prehospital Delay in Stroke Treatment
Stroke is the second-leading cause of death worldwide and a leading cause of long-term disability. Annually 12,000 people in Denmark suffers a stroke; half of them will have long-term disabilities that may affect the activities…
- Trial name
- NCT03759691
- Testing
- Structured interview
- Where
- 2 sites in Denmark
- Volunteers
- 650 people
- Sponsor
- University of Aarhus
Stroke
Determining the Optimal Dose of Reactive Balance Training After Stroke
Falls in daily life are one of the most significant complications for people with stroke. Fall rates are particularly high soon after discharge from stroke rehabilitation.
- Trial name
- NCT04219696
- Testing
- Reactive balance training
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Toronto Rehabilitation Institute
Stroke, Stroke Rehabilitation
Volunteer Facilitated Discharge Assistance and Supports at Home (DASH) for People With Stroke
The goal of this clinical trial is to learn if a home visit by a trained volunteer can improve stroke recovery after a stroke survivor is discharged home from the hospital. The main questions it aims to answer are: 1.
- Conditions
- Stroke, Stroke Rehabilitation, Transitional Care
- Trial name
- DASH (NCT07590076)
- Testing
- Discharge Assistance and Supports at Home (DASH)
- Where
- 6 sites in Canada
- Volunteers
- 840 people
- Sponsor
- Bruyère Health Research Institute.
Intracerebral Hemorrhage
Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial
Rationale: Management of blood pressure (BP) in the acute phase of intracerebral hemorrhage (ICH) remains controversial. Although it has been established that there is a transient moderate reduction of perihematoma cerebral blood…
- Trial name
- ICH ADAPT (NCT00963976)
- Testing
- labetalol/hydralazine/enalapril
- Where
- 4 sites in Canada
- Volunteers
- 74 people
- Sponsor
- University of Alberta
Stroke
Blood Pressure Level and Prognosis in Acute Stroke
Stroke is the leading cause of mortality in Brazil. Strict blood pressure control in chronic phase is the major measure to primary and secondary prevention, but in acute phase is not clear the best blood pressure level.
- Trial name
- NCT01195350
- Where
- Brazil
- Volunteers
- 266 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Stroke
Validation IMU and EMG Algorithms in Stroke Patients
The objective is to validate the algorithms for movement analysis that were developed previously in healthy participants, in a small study with stroke patients.
- Trial name
- NCT05205824
- Testing
- algorithm validation
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Roessingh Research and Development
Aphasia, Nonfluent Aphasia
Neural Networks and Language Recovery in Aphasia From Stroke: fMRI Studies
The purpose of this research is to utilize functional magnetic resonance imaging (fMRI) to investigate brain reorganization for language behavior in stroke patients with aphasia.
- Conditions
- Aphasia, Nonfluent Aphasia, Stroke
- Trial name
- NCT00467103
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Ischemic Stroke
Multi-center, Prospective, Cohort Study to Evaluate the Relationship of Stroke Recurrence and Anti-platelet Resistance in Ischemic Stroke Patients
This cohort study will evaluate the relatiobship of stroke recurrence and anti-platelet resistance in ischemic stroke patients
- Trial name
- NCT03823274
- Testing
- Aspirin, Clopidogrel
- Where
- South Korea
- Volunteers
- 1,011 people
- Sponsor
- Yuhan Corporation
Stroke, Repetitive Transcranial Magnetic Stimulation
Effect of Cerebral and Cerebellar rTMS in Stroke Patient
This study is based on the characteristics of motor learning theory and motor learning neural network to improve motor function in stroke patients.
- Conditions
- Stroke, Repetitive Transcranial Magnetic Stimulation, rTMS, Motor Recovery
- Trial name
- NCT04570774
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Stroke, Ischemic
Implementation of New Multimodal MRI Sequences by Fingerprint to Improve Ischemic Stroke Examination.
Currently, standard brain MRI takes 20 to 25 minutes, but in the case of ischemic stroke, every minute counts to limit the extension of the necrotic core, with the possibility of recanalizing the occluded artery (intravenous…
- Trial name
- INDEX (NCT07199920)
- Testing
- Achieva 3.0T dStream Philips
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble
Subarachnoid Hemorrhage, Aneurysmal, Poor Grade Subarachnoid Hemorrhage
Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group
Multicentric registry study in order to define outcome, predictors, treatment effects and their modifiers in poor grade aneurysmal subarachnoid haemorrhage patients.
- Trial name
- POGASH (NCT04945603)
- Testing
- Standard management according to international/national guidelines
- Where
- 10 sites in Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS San Raffaele
Stroke, Hemiparesis
Vibrotactile Feedback to Improve Walking After Stroke
Stroke survivors often walk more slowly and may have difficulty producing the movements needed to walk efficiently. This study will evaluate whether vibrotactile feedback, delivered through small wearable devices that provide…
- Trial name
- NCT07831642
- Testing
- Vibrotactile Feedback System
- Volunteers
- 32 people
- Sponsor
- Geisinger Clinic
Chronic Post Stroke Individuals
Recovering Arm Function in Chronic Post-stroke Patients Using Combined HD-tDCS and Virtual Reality Therapy
The study aims to determine the added value of combining high-definition transcranial direct current stimulation (HD-tDCS) in a rehabilitation program based on virtual reality therapy (VRT) to potentiate the effects on…
- Trial name
- ReArm (NCT04291573)
- Testing
- HD-tDCS
- Where
- France
- Volunteers
- 58 people
- Sponsor
- University Hospital, Montpellier
Hypertension
Reach Out: Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health Systems
This study evaluates a health theory based mobile health behavioral intervention to reduce blood pressure (BP) among hypertensive patients evaluated in a community Emergency Department (ED) setting.
- Trial name
- ReachOut ED (NCT03422718)
- Testing
- Healthy Behavior Texts, No healthy behavior texts, BP Monitoring Daily Via Text Messaging
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Michigan
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