Clinical trials: Cerebrovascular Diseases
Stroke
Effects of Task-Oriented Training With and Without Rhythmic Auditory Stimulation in Post-Stroke Patients
Stroke is one of the leading causes of long-term disability worldwide. Among survivors, limitations in lower limb motor function, balance, and proprioception significantly affect their independence and quality of life.
- Trial name
- NCT07724730
- Testing
- Task-Oriented Training + Rhythmic Auditory Stimulation, Task-Oriented Training Only
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Acute Ischemic Stroke
An Application Provides Temperature-related Health Risk Warnings and Protective Recommendations on Stroke
This study applied an application to provide early warnings and advice for stroke patients and explored the impact of this intervention on reducing the risk of stroke recurrence
- Trial name
- NCT07097428
- Testing
- Temperature health risk early warning
- Volunteers
- 5,092 people
- Sponsor
- Xuanwu Hospital, Beijing
Mild Cognitive Impairment
NAD Therapy for Improving Memory and Brain Blood Flow in Older Adults With Mild Cognitive Impairment
This study will provide insight into whether a nutritional supplement, nicotinamide riboside (NR), improves memory and brain blood flow in older adults with low memory abilities.
- Trial name
- NCT03482167
- Testing
- Niagen®
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Delaware
Subarachnoid Hemorrhage, Aneurysmal
Induced Suppression of Platelets Activity in Aneurysmal SAH Management (iSPASM)
This is a phase 1/2a, randomized, double blind, single-center study comparing standard care alone to standard care with Aggrastat in patients diagnosed with aneurysmal subarachnoid hemorrhage.
- Trial name
- NCT03691727
- Testing
- tirofiban hydrochloride (AGGRASTAT®), MRI, Neurological Exam
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- David Hasan
Cerebrovascular Disorder, Healthy
Magnetic Resonance Imaging Studies of Motor and Thought Processes
Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation).
- Conditions
- Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease
- Trial name
- NCT00001361
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Clinical Outcome Modelling of Rapid Dynamics in Acute Stroke
Stroke - still the second commonest cause of death and principal cause of adult neurological disability in the Western World - is characterised by rapid changes over time and marked variability in outcomes.
- Trial name
- NCT04641286
- Testing
- Body motion categorisation
- Where
- United Kingdom
- Volunteers
- 8,000 people
- Sponsor
- King's College Hospital NHS Trust
Mild Cognitive Impairment (MCI)
Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity
The goal of this clinical trial is to determine whether the extra-virgin olive oil (EVOO) phenolic dietary supplement can improve memory function and modulate biomarkers among individuals with mild cognitive impairment (MCI).
- Trial name
- ATHENA (NCT07741773)
- Testing
- EVOO-phenolics dietary supplement
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Augusta University
Stroke, Caregiver Burden
Family-centered Support Program for Caregivers of Stroke Survivors
The goal of this study is to evaluate the effect of a family-centered support program on the care burden, depressive symptoms, perceived social support, and quality of life of stroke survivor' caregivers and on care recipients'…
- Trial name
- NCT05668169
- Testing
- Family-centered support program for caregivers of stroke survivors
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- wen yu Kuo, assistant professor
Acute Effect of Local Vibration Application in Stroke Patients
Acute Effect of Local Vibration in Stroke Patients
The aim of the research is to examine the acute effect of local vibration application on gait and balance in stroke patients.
- Trial name
- NCT06610994
- Testing
- local vibration apply
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Myocardial Depression, Takotsubo Syndrome
Predicting the Development of Myocardial Depression in Acute Neurological Patients
The purpose of this study is to assess the levels of serum catecholamines associated with myocardial depression (MD) in patients with acute neurological injury.
- Conditions
- Myocardial Depression, Takotsubo Syndrome, Subarachnoid Hemorrhage, Acute Ischemic Stroke
- Trial name
- NCT03801694
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ohio State University
Acute Ischemic Stroke
Arterial Spin Label Depicted Ischemic Stroke Cohort (ASLIS)
Establish a clinical cohort of acute ischemic stroke patients and find the determinant of the prognosis.
- Trial name
- ASLIS (NCT05920902)
- Testing
- routine therapy of acute ischemia stroke
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Death, Carotid Artery Disease
NOR-SYS: The Norwegian Stroke in the Young Study
NOR-SYS is a clinical research program about young ischemic stroke patients from 15 to 60 years. Patients, partners and the couple´s adult children who are at least 18 years old, are all invited to ultrasound examinations due to…
- Conditions
- Death, Carotid Artery Disease, Cardiovascular Disease, Peripheral Artery Disease
- Trial name
- NOR-SYS (NCT01597453)
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Stroke, Rehabilitation
Effectiveness of Mindfulness-based Cognitive Therapy Undergoing Post Stroke Rehabilitation
The goal of this clinical trial is to investigate the efficacy of mindfulness-based cognitive therapy compared to usual care for stroke survivors undergoing inpatient rehabilitation.
- Conditions
- Stroke, Rehabilitation, Mindfulness
- Trial name
- NCT05844722
- Testing
- Mindfulness-based intervention therapy, usual care
- Where
- Hungary
- Volunteers
- 93 people
- Sponsor
- National Institute for Medical Rehabilitation, Hungary
Coronary Heart Disease, Stroke
The Copenhagen City Heart Study
The Copenhagen City Heart Study is an ongoing cardiovascular population study initiated in 1976 which has examined approximately 25,000 individuals from the general population.
- Conditions
- Coronary Heart Disease, Stroke, Heart Failure, Cancer
- Trial name
- CCHS (NCT02993172)
- Volunteers
- 23,891 people
- Sponsor
- Bispebjerg Hospital
Parkinson Disease, Stroke
Smart Wearable Device (gaitQ): Walk Better Project
This study will be underpinned by the new MRC guidelines for developing a complex intervention with a participatory design methodology that uses evidence-based research and behaviour change models alongside COSMIN methodology for…
- Conditions
- Parkinson Disease, Stroke, Multiple Sclerosis, Osteoporosis
- Trial name
- NCT05913219
- Where
- United Kingdom
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Functional Independence, Respiratory Insufficiency
More Air - Better Performance - Faster Recovery
The objective of this study is to investigate i) the effect of 3 weeks IMT to adults post-stroke to maximal inspiratory pressure (MIP) and ii) the effects of 3 weeks IMT to the degree of dependency in activities of daily living…
- Trial name
- IMT (NCT04686019)
- Testing
- Inspiratory muscle training (IMT)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Central Jutland Regional Hospital
Cerebral Vasospasm, Subarachnoid Hemorrhage
Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm
Rupture of a cerebral aneurysm is a serious medical condition that may result in permanent disability or even death just related to the aneurysm rupture itself.
- Trial name
- NCT00871065
- Testing
- Sildenafil citrate
- Sponsor
- University of Nebraska
Stroke
The Outcomes of Seamless ADL Training Between Occupational Therapist and Nurse in Stroke Patients
This study aimed to develop and implement an interdisciplinary team model with integration of all the relevant expertise and to establish powerful collaboration and communication among the team.
- Trial name
- NCT02361307
- Testing
- Seamless ADL training, Conventional ADL training
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University
Carotid Stenosis, Ischemic Stroke
Symptomatic Carotid Outcomes Registry
The purpose of this study is to build upon trials done over 30 years ago, which did not include statins, new antiplatelet agents, and newer antihypertensive medications.
- Conditions
- Carotid Stenosis, Ischemic Stroke, Transient Ischemic Attack
- Trial name
- SCORE (NCT05300737)
- Testing
- intensive medical therapy
- Where
- 18 sites in United States, Canada
- Volunteers
- 114 people
- Sponsor
- University of Maryland, Baltimore
Carotid Artery Diseases, Carotid Artery Stenosis
Timing Carotid Stent Clinical Study for the Treatment of Carotid Artery Stenosis（Timing Trial）
Evaluate the safety and efficacy of the Timing Carotid Stent for the treatment of carotid artery stenosis in patients.
- Conditions
- Carotid Artery Diseases, Carotid Artery Stenosis, Stroke, Ischemic Stroke
- Trial name
- NCT05574972
- Testing
- Timing Carotid Stent, Carotid Wallstent
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Suzhou Zenith Vascular SciTech Limited
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