Clinical trials: Cerebrovascular Function
Stroke
Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond traditional stimulation which targeting only one region.
- Trial name
- NCT05638464
- Testing
- multisite HD-tDCS EMG-driven robot hand
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dementia, Alzheimer Disease
Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias
The investigators aim to study the effects of a 24-week remote-based resistance exercise training program on cardiovascular disease risk factors, cognitive function, and quality of life in older adults living with mild cognitive…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT05004558
- Testing
- Remote-based Resistance Exercise Training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Diabetes Mellitus, Type 2, Hypertension
Study of the Relationship Between Blood Vessels and Insulin Response in Adolescents
This study is designed to determine whether there is a relationship between the way insulin and blood vessels work. The difference in the interaction between Caucasian and African American adolescents will also be examined.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Heart Disease, Stroke
- Trial name
- NCT00374361
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Blood Pressure
The Effect of Whey Protein Supplementation on Vascular and Cognitive Function in Older Adults
The "hardening of the arteries" observed with aging raises blood pressure and contributes to poor brain blood flow and loss of cognitive function (i.e. attention, memory, solving problems, making decisions).
- Trial name
- NCT01956994
- Testing
- Whey protein supplement, Carbohydrate supplement
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Ischemic Stroke
Cortex Motor Function Reorganization in Stroke Patients
In China, stroke is among the highest morbidity and mortality, especially in senile population. Most of those patients had survived with various degrees of cerebral dysfunction; among them about 50% were motor deficit.
- Trial name
- NCT04794673
- Testing
- brain damage
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Stroke
The Effect of Trunk Control on Sitting Balance and Upper Extremity Functions in Patients With Subacute Stroke
The study aims to examine whether trunk control affects sitting balance and upper extremity functions in patients with subacute stroke.
- Trial name
- NCT06059482
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
HR Vaiability, Aerobic Physical Fitness,Blood Pressure, Blood Sugar Level, Blood HDL, LDL
Aerobic Exercise Training & the Autonomic System In Patients After Myocardial Infarction or Stroke
The purpose of this study is to examine the effect of Aerobic Physical Activity on the function of the Autonomic System in patients after Myocardial Infarction or Stroke.
- Trial name
- NCT00259948
- Testing
- Aerobic exercise training
- Where
- Israel
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Stroke
fNIRS for Monitoring Cortical Activity in Stroke Recovery
This clinical trial aims to investigate the mechanisms of brain reorganization underlying motor recovery following end-effector (EE) and exoskeleton (Exo) robot-assisted hand training in individuals with stroke.
- Trial name
- NCT07623512
- Testing
- Robot-assisted therapy (EE or EXO system) and functional training
- Where
- Taiwan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Transcranial Alternating Current Stimulation for Hand Function Recovery
tACS has the potential to directly induce cortical alterations in the intrinsic neural oscillation at specific frequencies, and the brain could mirror the induced frequencies of the external source of oscillations from the…
- Trial name
- NCT04638192
- Testing
- tACS
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Ischemic Stroke
Discovering Patterns in the Gut Microbiota Associated With the Risk of Stroke and the Outcome After a Stroke and Integration of These Data With Genomic Information to Find New Drug Targets and New Treatments to Improve Neurological Evolution and Functional Status of Stroke Patients.
The composition of the intestinal microbiota is associated with the risk of stroke and with post-stroke neurological evolution. At the same time, the genetics and epigenetics of each patient are associated with the composition of…
- Trial name
- MAESTRO (NCT04795687)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Stroke, Hemiparesis
Recovery of Motor Skills With the Use of Artificial Intelligence and Computer Vision
To investigate the impact of algorithms utilizing artificial intelligence technology and computer vision on the recovery of motor functions within the context of rehabilitation practice for patients who have experienced a…
- Conditions
- Stroke, Hemiparesis, Spasticity as Sequela of Stroke, Dysmetria
- Trial name
- NCT06183970
- Testing
- AssistI patients, Habilect patients
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Chest Pain, Pneumonia
The Effect of Exercise on Physical Function and Health in Older People After Discharge From Hospital
The aim of this study is to investigate the effect of a multi-component exercise program on physical function, physical activity and health-related quality of life (HRQOL) in older people recently discharged from hospital.
- Conditions
- Chest Pain, Pneumonia, Transient Ischemic Attack, Stroke
- Trial name
- OLPADIS (NCT02905383)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Stroke
Understanding Motor Function in Stroke Patients and Their Functional Brain Reorganization Using Ultra High-field MRI
The MOTIF-STROKE study is embedded within the BrainSync project, aiming to develop innovative strategies for motor rehabilitation of the upper limb.
- Trial name
- MOTIF-STROKE (NCT07339813)
- Testing
- Functional MRI (fMRI) Acquisition
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Muscle Weakness
Respiratory Muscle Training in Subacute Stroke Patients
This study is divided for development in two complementary work packages justified by the need to incorporate new strategies to optimize rehabilitation outcomes in stroke patients.
- Trial name
- RETORNUS (NCT02125760)
- Testing
- Inspiratory Muscle Training (IMT), High-intensity IMT
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Stroke, Stroke, Ischemic
Efficacy of REMO Training for Hand Motor Recovery After Stroke
Upper limb motor impairment is one of the most common sequelae after stroke. Indeed, the recovery of upper limb sensory-motor functions remains one of the most important goals in stroke rehabilitation.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke Sequelae
- Trial name
- REMO (NCT05815368)
- Testing
- REMO, Task-Oriented Training
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Stroke, Hemiparesis
Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.
- Trial name
- NCT06598150
- Testing
- Shoulder Abduction
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Stroke
Action Observation Therapy in Chronic Stroke
Functional impairment in the upper extremities is one of the most common sequelae in stroke patients. It significantly limits the patients' grasping-releasing functions and, consequently, their activities of daily living (ADL)…
- Trial name
- NCT06794749
- Testing
- Action Observation Therapy, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Stroke
Exercise and Genotype in Sub-acute Stroke
This study will investigate the impact of cardiovascular exercise on brain plasticity among patients in sub-acute stages after stroke, and whether genotype modulates the response to this intervention.
- Trial name
- NCT05076747
- Testing
- Cardiovascular training, Standard Therapy
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- McGill University
Stroke
Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke
Stroke (795,000/year in the US and 30 million existing stroke survivors in the world) damages brain neural structures that control coordinated upper limb movement.
- Trial name
- NCT02856035
- Testing
- Neural feedback plus FES and motor training
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Carotid Artery Stenosis, Image
Evaluation of Brain Health and Surgical Efficacy in Patients With Carotid Artery Stenosis
The purpose of this study is to explore the relationship between the recovery of cerebrovascular morphology and cognitive function before and after surgical treatment in patients with carotid artery stenosis and their…
- Trial name
- NCT05848921
- Testing
- magnetic resonance image, Neuropsychological scale
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing University of Traditional Chinese Medicine