Clinical trials: Cerebrovascular and Cardiovascular Diseases
Stroke, Chronic Disease
AR Training Platform at Home
Video Communications, like ZOOM, have been widely used in the time of this epidemic. But how about to design an AR / VR communication system with coaching from clinician to facilitate training at home in this time of epidemic.
- Trial name
- NCT05627050
- Testing
- An Online Augmented Reality (AR) Training Platform
- Where
- Hong Kong
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Intracranial Atherosclerosis
Predicting Stroke Risk in ICAD With Novel MRI
The cerebral and spinal vasculature possesses several unique properties: it is composed of relatively small vessels, it has a highly connected network architecture, and, due to the confined space around the brain, disruptions in…
- Trial name
- NCT05515874
- Testing
- Feraheme
- Where
- United States
- Sponsor
- Northwestern University
Stroke
Dry Needling in Patients Who Had Experience Stroke
Individuals who had experience a stroke usually suffer from spasticity at medium and long-terms. The presence of spasticity in the lower extremity implies several impairments for standing and walking inducing high disability.
- Trial name
- NCT02579291
- Testing
- Dry needling, Bobath
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Rey Juan Carlos
Stroke
A Cognitive-Augmented Mobility Program
This project will combine best-evidence gait and mobility training with best evidence cognitive strategy training to produce a new cognitive-augmented mobility intervention that is expected to optimize long-term functional…
- Trial name
- CAMP (NCT03683160)
- Testing
- Cognitive Augmented Mobility Program
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke (CVA) or TIA
Functional Electrical Stimulation Versus Whole-Body Vibration in Post-Stroke Rehabilitation
This study will compare the effects of Functional Electrical Stimulation (FES) and Whole Body Vibration Training (WBVT) on lower limb motor control, balance, and physical performance in post-stroke patients.
- Trial name
- NCT07629882
- Testing
- Functional Electrical Stimulation, Whole Body Vibration Training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Patients in Minimally Conscious State After a Severe Brain Injury
tDCS on Precuneus in MCS: Repeated Stimulations
In this study researchers will apply transcranial direct current stimulation (tDCS) for 5 consecutive days in chronic patients in minimally conscious state (MCS).
- Trial name
- NCT02702362
- Testing
- transcranial direct current stimulation
- Volunteers
- 33 people
- Sponsor
- Hangzhou Normal University
Non-valvular Atrial Fibrillation
Safety and Effectiveness of Apixaban in Very Elderly Patients With Non-valvular Atrial Fibrillation (NVAF) Compared to Warfarin Using Administrative Claims Data
The objective of this study is to investigate safety and effectiveness of apixaban compared to warfarin in very elderly patients with Non-valvular atrial fibrillation (NVAF).
- Trial name
- NCT05438888
- Testing
- Warfarin, Apixaban
- Where
- Japan
- Volunteers
- 77,814 people
- Sponsor
- Pfizer
Cerebral Infarction
Contrast Enhanced Ultrasound of Carotid Plaque in Acute Ischemic Stroke
This is a biomedical, single-center, and prospective study of a consecutive patients cohort in acute ischemic stroke with carotid plaque.
- Trial name
- CUSCAS (NCT03115242)
- Testing
- Contrast injection Sonovue®
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Versailles Hospital
Stroke
Cranial Nerve Neuromodulation to Improve Arm Function and Brain Plasticity in Stroke
Following a stroke, persistent residual muscle weakness in the upper limb (UL) drastically impacts the individuals' quality of life and level of independence.
- Trial name
- CN-NINM (NCT06386510)
- Testing
- Strength training, Cranial nerve non-invasive neuromodulation
- Where
- 3 sites in Canada
- Volunteers
- 74 people
- Sponsor
- Université de Sherbrooke
Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA), Churg-Strauss Syndrome (CSS)
The ANCA Vasculitis Questionnaire (AAV-PRO©)
The aim of this project is to develop a disease specific patient reported outcome measure (PROM) for patients with AAV (the AAV-PRO).
- Conditions
- Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA), Churg-Strauss Syndrome (CSS), Granulomatosis With Polyangiitis (Wegener's) (GPA), Wegener Granulomatosis (WG)
- Trial name
- AAV-PRO (NCT02507024)
- Testing
- Online questionnaire
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- University of Pennsylvania
Intracerebral Hemorrhage
Dimethyl Fumarate for the Treatment of Intracerebral Hemorrhage
The investigators conduct this study to investigate whether oral administration of Dimethyl Fumarate, a Food and Drug Administration-approved drug for multiple sclerosis, is safe and effective in alleviating PHE and neurologic…
- Trial name
- NCT04890379
- Testing
- Dimethyl fumarate
- Where
- China
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
Effects of Strength Training of Non-paretic Upper and Lower Limb With or Without Mirror Therapy
The aim of this study is to find the effects of strength training with or without mirror therapy of non-paralytic upper limb for functional activities and in lower limb for gait pattern, balance and stability, and ADLs of…
- Trial name
- NCT06292403
- Testing
- Strength Training, Mirror therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Intracerebral Hemorrhage
Statins In Intracerbral Hemorrhage
The SATURN trial aims to determine whether continuation vs. discontinuation of statin drugs after spontaneous lobar intracerebral hemorrhage (ICH) is the best strategy; and whether the decision to continue/discontinue statins…
- Trial name
- SATURN (NCT03936361)
- Testing
- Statins
- Where
- United States
- Volunteers
- 1,456 people
- Sponsor
- Beth Israel Deaconess Medical Center
Mucopolysaccharidosis, Fabry Disease
Non-invasive Assessment of Intraocular Pressure in MPS by Use of the Ocular Response Analyzer.
The aim of the present study is to compare intraocular pressure (IOP) values assessed with Ocular Response Analyzer to the classical gold standard of IOP measurement, to Goldmann applanation tonometry by mucopolysacchyridosis…
- Trial name
- MPSORA (NCT01695161)
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Stroke
The Relationship Between Kinesiophobia, Mobility, Postural Control and Fear of Falling in Patients With Stroke
Stroke is a sudden decrease or cessation of blood flow to the brain. Two specific types of stroke account for the majority of stroke cases.
- Trial name
- NCT06088342
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uskudar University
Pelvic Floor Muscle Weakness, Stroke
Multimodal Pelvic Floor Rehabilitation in Chronic Stroke Survivors: Long-Term Efficacy, Optimal Protocols, and Adjunctive Therapies for Comprehensive Pelvic Floor Dysfunction.
Evaluate long-term efficacy of multimodal PFMT in chronic stroke survivors with PFD.
- Trial name
- RCT (NCT07420569)
- Testing
- Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks. • Group A (Standard PFMT): 3 supervised/week (weeks 1-8), 1/week (9-16) + home. • Group B (Intensified PFMT): 5/week, Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks.
- Where
- Uganda
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iqra National University
Stroke
Robot-assisted Therapy Combined With Mirror Priming in Upper Limb Training in Stroke
This project will employ the robot-assisted system to assist patients to perform the grasping and releasing movement of both hands simultaneously while mirror priming strategy is applied, and, then, perform intensive and…
- Trial name
- NCT04326140
- Testing
- mirror therapy, robotic-assisted training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Hydroxyurea to Prevent Stroke in Children With Sickle Cell Anemia and Elevated TCD Flow Velocity
The purpose of this study is to assess prospectively the efficacy of hydroxyurea therapy in the setting of cerebrovascular disease, manifest as conditional or abnormal transcranial doppler ultrasonography (TCD) flow velocities…
- Trial name
- NCT00402480
- Testing
- Hydroxyurea
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Aphasia, Primary Progressive Aphasia
Circuitry Assessment and Reinforcement Training Effects on Recovery
This study investigates if electroencephalography (EEG) neurofeedback training is more beneficial than sham feedback training for the improvement of communication, anxiety, and sleep quality in individuals with aphasia.
- Conditions
- Aphasia, Primary Progressive Aphasia, Stroke
- Trial name
- CARTER (NCT04290988)
- Testing
- EEG Neurofeedback
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Johns Hopkins University
Stroke, Atrial Fibrillation
Clinical Characteristics and Prognosis of Acute Cerebrovascular Events Secondary to Patients Receiving Cardiac Electronic Implants
To investigate the incidence, clinical characteristics and prognosis of acute ischemic and hemorrhagic cerebrovascular disease secondary to the implantation of cardiovascular implantable electronic devices, so as to provide a…
- Conditions
- Stroke, Atrial Fibrillation, Pacemaker
- Trial name
- SOS-CARE (NCT05623527)
- Testing
- cardiac electronic implants
- Where
- China
- Volunteers
- 13,324 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
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