Clinical trials: Cervical Dilation
Labour Onset and Length Abnormalities, Labor; Forced or Induced, Affecting Fetus or Newborn
Dilapan-S/Dilasoft E-Registry in Induction of Labor
International Observational E-Registry on the use of DILAPAN-S® osmotic dilator / DILASOFT® osmotic dilator for cervical ripening prior to labour induction.
- Trial name
- DSREGISTRYIL (NCT02318173)
- Testing
- Dilapan-S
- Where
- 11 sites in United States, Czechia and 5 more
- Volunteers
- 444 people
- Sponsor
- Medicem International CR s.r.o.
Labor Onset Biomarkers, Labor Onset
Pregnancy and Latent Labor Biomarkers and Symptoms to Predict Cervical Dilation at Hospital Admission.
The proposed pilot investigation is a prospective, observational study of 300 healthy nulliparous women with spontaneous term labor onset.
- Conditions
- Labor Onset Biomarkers, Labor Onset, Cervical Dilation
- Trial name
- NCT04437576
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Abortion, Induced
Cervical Priming Before Dilation & Evacuation
The purpose of this study is to compare the efficacy of buccal misoprostol cervical priming to laminaria priming among women undergoing D\&E at 13-20 weeks gestation in the Western Cape Province, South Africa
- Trial name
- NCT01597726
- Testing
- Misoprostol, Laminaria
- Where
- South Africa
- Volunteers
- 159 people
- Sponsor
- Ibis Reproductive Health
Hysteroscopy, Cervical Ripening
Significance of Misoprostol-induced Cervical Ripening Prior to Hysteroscopy
The goal of this prospective study is to evaluate the efficacy and safety of misoprostol for cervical ripening prior to hysteroscopy
- Trial name
- NCT06726278
- Testing
- Misoprostol 400mcg Tab
- Where
- Pakistan
- Volunteers
- 539 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Esophageal Stenosis, Deglutition Disorders
Endoscopic Injection of Mitomycin C for the Treatment of Pharyngoesophageal Stenosis
Management of pharyngoesophageal stenosis (PES) in patients after head and neck cancer (HNC) treatment remains a challenge. There are some cases of strictures refractory to dilation sessions.
- Conditions
- Esophageal Stenosis, Deglutition Disorders, Head and Neck Neoplasms, Esophageal Neoplasms
- Trial name
- NCT03540953
- Testing
- Endoscopic injection of Mitomycin C
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Fauze Maluf Filho
Abortion, Induced
Cervical Preparation Before Dilation and Evacuation
The purpose of this research study is to compare three different ways of opening a woman's cervix before her second-trimester surgical abortion.
- Trial name
- NCT01751087
- Testing
- Mifepristone, misoprostol, Osmotic dilators
- Where
- 7 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Pain
12 Versus 20 mL PCB for D&E Cervical Prep
More research is needed to investigate methods of pain control for cervical preparation for abortion procedures. Women report pain with paracervical block injection as well as with osmotic dilator placement.
- Trial name
- NCT03356145
- Testing
- 12 mL paracervical block, 20 mL paracervical block
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Labor Active Dilated Cm
Decision-Making in Labor Admission Using Transperineal Ultrasound vs. Vaginal Examination
This clinical trial aims to determine whether transperineal ultrasound (a perineal external scan) can improve decision-making for hospital admission in term pregnant women in labor compared to traditional vaginal examination.
- Trial name
- NCT07278271
- Testing
- Transperineal Ultrasound, Vaginal Examination
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- Hospital Universitario La Paz
Legally Induced Abortion Without Mention of Complication
Pre-Operative Effects of Mifepristone on Dilation and Evacuation Services
This research study investigates the use of a drug, mifepristone, given before second trimester abortion. Mifepristone is a medication that is approved for medical abortion during the first trimester.
- Trial name
- POEM (NCT01862991)
- Testing
- Hygroscopic cervical dilators, Misoprostol, Intra-amniotic digoxin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Esophageal Disruption, Esophageal Obstruction
Evaluation of the Effectiveness of Endoscopic "Rendez-vous" Technique Foresophageal Reconstructions for the Treatment of a Total and Extensive Disruption of the Esophagus
Complete esophageal obstructions leads to definitive fasting. The rendez-vous endoscopic approach had already been described for complex stenoses but never for disruption with loss of tissue and SES.
- Trial name
- NCT02166957
- Testing
- Recanalization
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Société Française d'Endoscopie Digestive
Failure of Cervical Dilatation, Complications; Cesarean Section
Is Routine Cervical Dilatation Necessary During Elective Caesarean Section? A Randomised Controlled Trial
The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity
- Conditions
- Failure of Cervical Dilatation, Complications; Cesarean Section, Wound Infection,, External Causes of Morbidity and Mortality
- Trial name
- NCT01954719
- Testing
- cervix dilated after surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cervical Priming
Efficacy and Safety Study of the Misoprostol Vaginal Priming Insert (MVPI) Prior to Hysteroscopy
A Phase II, multicenter, double-blind, randomized, placebo-controlled, dose-ranging, study to assess the efficacy and safety of the 100, 200, 400, 800, 1200 and 1600 mcg Misoprostol Vaginal Priming Insert (MVPI) for Women…
- Trial name
- NCT00925938
- Testing
- misoprostol
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Ferring Pharmaceuticals
Induced Vaginal Delivery, Induced; Birth
Outpatient Transcervical Balloon For Induction of Labor
The goal of this randomized control trial is to compare outpatient transcervical foley balloon to inpatient vaginal misoprostol in pregnant women for cervical ripening. The main questions it aims to answer are: 1.
- Trial name
- NCT05798728
- Testing
- Outpatient transcervical foley balloon, Inpatient Vaginal Misoprostol
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hurley Medical Center
Cervix; Pregnancy
Sound Check-Correlation Between Transperineal and Digital Cervical Exam in 3rd Trimester Pregnancy
The primary purpose of this study is to compare the accuracy of the Butterfly iQ pocket ultrasound with the digital cervical examination in the third trimester cervix.
- Trial name
- NCT05260333
- Testing
- Butterfly iQ transperineal ultrasound exam
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pre-induction Dilation of Cervix
Induction of Labor in Women With Unfavorable Cervix: Dilapan Versus Foley Bulb
Women undergoing mechanical cervical ripening for labor induction will be randomized to Dilapan-S® versus Foley bulb. The investigators hypothesized that osmotic cervical dilators (Dilapan-S®) are as effective as Foley bulb…
- Trial name
- NCT02899689
- Testing
- Dilapan, Foley Catheter
- Where
- 2 sites in United States
- Volunteers
- 419 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Labor Pain
Epidural Analgesia in Different Cervix Diameter and the Rate of Cesarean Delivery
Epidural analgesia in the early stage of labor at cervix < 4.0cm was considered as a risk period for increasing the rate of cesarean delivery.
- Trial name
- EACDRCD (NCT00677274)
- Testing
- Epidural labor analgesia
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Nanjing Medical University
Induced; Birth, Cervical Dilatation
Induction to Labour With Double Cervical Ballon at Home Versus at Hospital
The goal of this clinical trial] is to compare the outcomes between induction to labour at home versus hospitalized. The main questions it aims to answer are: Can the induction to labour at home with cervical rippening ballon…
- Conditions
- Induced; Birth, Cervical Dilatation, Live Birth
- Trial name
- INDOBAMHOS (NCT06053073)
- Testing
- Cervical rippening at home, Cervical rippening in the hospital
- Where
- Spain
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Virtual Reality, Educational
The Effect of Virtual Reality Application in Cervical Dilatation and Effacement Teaching
The aim of this project is to determine the effect of virtual reality application in cervical dilatation and effacement teaching on students' satisfaction, confidence and anxiety levels.
- Trial name
- NCT05982457
- Testing
- virtual reality group
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Sevgi Beyazgül
Esophageal Cancer
Balloon Dilation to Permit Complete Endoscopic Ultrasound Staging in Esophageal Cancer
Despite improvement in treatment-related morbidity and mortality, esophageal cancer is still one of the most lethal malignancies. Accurate staging is essential to establish prognosis and for patient management.
- Trial name
- CT0046 (NCT01950442)
- Testing
- Balloon dilation
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Endometrial Biopsy
Oral Misoprostol Before Endometrial Biopsy
An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus.
- Trial name
- NCT00200226
- Testing
- misoprostol, vitamin B6
- Where
- 2 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland