Clinical trials: Cervical Dystonia
Torticollis, Muscle Spasticity
Botulinum Toxin Injection Efficiency
The purpose of the study is to examine the effect of the botulinum toxin injection into muscle tone, strength and mobility with and without muscle exercise effect.
- Trial name
- NCT01041157
- Testing
- Resistance training
- Where
- Finland
- Volunteers
- 22 people
- Sponsor
- Jyväskylä Central Hospital
Dystonia, Torticollis
The Physiology of Tricks
This study will examine the action of sensory tricks on an occurrence known as surround inhibition when there is a disorder of muscle tone affecting a single body part in isolation.
- Trial name
- NCT00072956
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dystonia, Cervical
Exercise Program for Patients With Cervical Dystonia Who Are Treated With Botulinum Toxin Type A
Dystonia is involuntary movements characterized by posture abnormalities or repetitive movements as a result of continuous or intermittent simultaneous contraction of opposing muscle groups.
- Trial name
- NCT05502718
- Testing
- Stretching and Strengthening Exercises, Breathing and Rhythmic Coordination Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Prof. Dr. Şehim Kutlay
Cervical Dystonia
Post-marketing Surveillance of Administration of Botulinum Toxin Type B(NerBloc)-Investigation of the Clinical Condition and Safety in Patients With Cervical Dystonia
Investigation of the clinical condition and safety in patients with cervical dystonia
- Trial name
- NCT02175693
- Where
- 2 sites in Japan
- Volunteers
- 1,647 people
- Sponsor
- Eisai Co., Ltd.
Torticollis
Effect of Botulinum Toxin Type A on Swallowing in Patients With Cervical Dystonia
The purpose of this study is to evaluate swallowing efficiency in patients with cervical dystonia following treatment with botulinum toxin Type A.
- Trial name
- NCT01384214
- Testing
- botulinum toxin Type A
- Where
- Croatia
- Volunteers
- 28 people
- Sponsor
- Allergan
Torticollis (Spasmodic)
Dose-escalating Safety and Preliminary Efficacy of DaxibotulinumtoxinA for Injection in Cervical Dystonia
This is an open-label, dose-escalation study to assess the safety and preliminary efficacy of daxibotulinumtoxinA in subjects with isolated cervical dystonia (CD).
- Trial name
- NCT02706795
- Testing
- DaxibotulinumtoxinA
- Where
- 13 sites in United States
- Volunteers
- 37 people
- Sponsor
- Revance Therapeutics, Inc.
Spasmodic Torticollis
An Electrophysiological Study Of E2014 In Healthy Adult Male Japanese And Caucasian Subjects
To evaluate inter-ethnic similarity in pharmacodynamics between Japanese and Caucasian healthy adult male subjects by comparing electrophysiological reactions after administering E2014 to extensor digitorum brevis muscle (EDB).
- Trial name
- NCT00280384
- Testing
- E2014 (Botulinum toxin type B)
- Where
- Japan
- Volunteers
- 48 people
- Sponsor
- Eisai Limited
Cervical Dystonia
Noninvasive Brain Stimulation for Cervical Dystonia
The primary aim of this study is to assess whether continuous theta-burst stimulation (cTBS) can be helpful in reducing symptoms of idiopathic cervical dystonia.
- Trial name
- NetworkStim (NCT07681284)
- Testing
- Active continuous theta-burst stimulation
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Cervical Dystonia
Deep Brain Stimulation to Treat Cervical Dystonia
This study will evaluate the effectiveness of deep brain stimulation (DBS) for treating primary dystonia. Patients with dystonia have muscle spasms that cause uncontrolled twisting and repetitive movement or abnormal postures.
- Trial name
- NCT00132340
- Testing
- Electrodes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Botulinum Toxin, Quality of Life
The Impact of Botulinum Toxin Treatment in Quality of Life of Cervical Dystonia Patients
The purpose of this study is to investigate the impact of botulinum toxin treatment in quality of life(QoL) in cervical dystonia patients
- Conditions
- Botulinum Toxin, Quality of Life, Cervical Dystonia
- Trial name
- NCT01664013
- Testing
- Nuronox
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Roongroj Bhidayasiri
Cervical Dystonia
Tele-yoga and Dystonia
The purpose of this study is to investigate the effect of yoga delivered remotely on adults with dystonia. This work will have implications related to physical interventions symptom management and quality of life as well as…
- Trial name
- NCT04348669
- Testing
- Tele-yoga
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Cervical Dystonia
Open Label Safety/Immunogenicity Study of MYOBLOC (Neurobloc; Botulinum Toxin Type B) in Patients With Cervical Dystonia
Open label study to evaluate the safety and immunogenicity of MYOBLOC (Botulinum Toxin Type B) in adult patients with a clinical diagnosis of Cervical Dystonia (CD).
- Trial name
- NCT00702754
- Testing
- Botulinum Toxin Type B
- Volunteers
- 502 people
- Sponsor
- Solstice Neurosciences, LLC, a subsidiary of US WorldMeds, LLC
Dystonia, Focal
Motor and Non-motor Symptoms in Cervical Dystonia
In this monocenter, observational, non-interventional, prospective, open label study investigators will enrol 43 CD patients from the outpatient Movement Disorders Clinic of the Department of Human Neurosciences, Sapienza…
- Trial name
- Royal (NCT04560101)
- Testing
- botulinum toxin A
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- University of Roma La Sapienza
Cervical Dystonia
Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia
The purpose of the protocol is to assess the long term safety of repeat treatment cycles of Dysport® 500 U using 2 mL dilution scheme for the treatment of Cervical Dystonia.
- Trial name
- NCT01753336
- Testing
- Botulinum toxin type A
- Where
- 41 sites in United States
- Volunteers
- 112 people
- Sponsor
- Ipsen
Cervical Dystonia
DYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia
The purpose of the protocol is to determine typical patient response to Dysport in the treatment of adult cervical dystonia (CD).
- Trial name
- ANCHOR-CD (NCT01314365)
- Where
- 45 sites in United States
- Volunteers
- 350 people
- Sponsor
- Ipsen
Cervical Dystonia, Spasmodic Torticollis
Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis
To evaluate efficacy and safety of E2014 (2500U, 5000U, 10000U, placebo) in a multicenter, randomized, double-blind, parallel group comparative study by intramuscularly administering to patients with spasmodic torticollis.
- Trial name
- NCT00165776
- Testing
- BOTULINUM TOXIN TYPE B
- Where
- 21 sites in Japan
- Volunteers
- 133 people
- Sponsor
- Eisai Co., Ltd.
Cervical Dystonia
Comparison of Pallidal With Subthalamic Deep Brain Stimulation for Cervical Dystonia
Cervical dystonia (CD), also known as spasmodic torticollis, is a type of focal dystonia, mainly manifesting as involuntary head turning or tilting, or holding a twisted posture.
- Trial name
- NCT05715138
- Testing
- GPi-DBS, STN-DBS, GPi-DBS devices
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese PLA General Hospital
Cervical Dystonia
Dystonia Treatment With Injections Supplemented By Transcranial Magnetic Stimulation
We applied 16 sessions of rTMS over 4 consecutive days for adult patients suffering from cervical dystonia who received botulinum toxin (BoNT) injections on a regular basis.
- Trial name
- D-TWIST (NCT04916444)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida
Cervical Dystonia
Conversion to Dysport in CD
The first line of therapy for cervical dystonia patients is botulinum toxin injections, however injection parameter determination and optimization are challenging for physicians to do.
- Trial name
- NCT04270214
- Testing
- Dysport Injectable Product
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Western University, Canada
Cervical Dystonia, Primary, Blepharospasm
Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal Dystonia
Efficient gait requires effective postural control, both static and dynamic. Hence, postural disorders may affect gait. Yet, very little is known about the specific effects of focal postural disorders such as cervical dystonia…
- Trial name
- GAIT-TOX (NCT03938363)
- Testing
- Treadmill, Botulinum Toxin injection, Severity scale of the disease
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble