Clinical trials: Cervical Spine Disc Disease
Cervical Spondylosis
Effectiveness and Safety of Mobile Artificial Cervical Vertebrae Replacement for Patients With Cervical Spondylosis
The research team designed an artificial cervical joint prosthesis suitable for subtotal resection of the lower cervical vertebral body.
- Trial name
- NCT04813211
- Testing
- mobile artificial cervical vertebrae replacement, anterior cervical corpectomy and fusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xi'an International Medical Center Hospital
Cervical Spondylosis, Cervical Radiculopathy
NuVasive® ACP System Study
The primary objective of this study is to evaluate the safety and performance of anterior cervical spine surgery using the NuVasive anterior cervical plate (ACP) System as measured by reported complications, radiographic…
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
- Trial name
- NCT05066711
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- NuVasive
Cervical Degenerative Disc Disease
Post Market Data Collection Protocol to Evaluate the Performance of the Synergy Disc
This is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts.
- Trial name
- NCT05880823
- Testing
- Synergy cervical disc system
- Where
- Germany
- Sponsor
- Synergy Spine Solutions
Radiculopathy, Myelopathy
RHINE™ Cervical Disc Clinical Study: A Prospective Observational Study for Patients Requiring 1-2 Level C-spine Surgery
A Prospective, open label, multi-center observational study of patients requiring surgical treatment at one or two (contiguous) cervical spine levels.
- Conditions
- Radiculopathy, Myelopathy, Spondylosis, Herniated Nucleus Pulposus
- Trial name
- NCT02403453
- Testing
- Rhine Cervical Disc
- Volunteers
- 68 people
- Sponsor
- K2M, Inc.
Cervical Disc Disorders
Clinical Outcome After Anterior Cervical Decompression and Fusion and Cervical Total Disc Replacement
The aim of this study is to examine the clinical outcome after anterior cervical decompression and fusion, and cervical disc prostheses in general.
- Trial name
- NCT02498028
- Testing
- Cervical Fusion, Cervical disc Prostheses
- Where
- 2 sites in Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital, Bonn
Spine Fusion, Lumbar Disc Herniation
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
Accelerated Postoperative Recovery (ERAS) is a multidisciplinary approach aimed at facilitating faster and more effective recovery for patients undergoing surgical procedures.
- Conditions
- Spine Fusion, Lumbar Disc Herniation, Cervical Disc Disease
- Trial name
- NCT06102681
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Duzce University
Degenerative Disc Disease, Spondylolisthesis
Quintex® Follow-up After One Year Minimum
Prospective study, not randomised, non-interventional, monocentric, investigating an intended patient cohort of 60 patients already operated on the cervical spine due to degenerative disc disease of the cervical spine down to the…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Trauma, Spinal Stenosis
- Trial name
- Quintex (NCT04489394)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Radiculopathy, Cervical, Myelopathy Cervical
Cervical Arthroplasty Cost Effectiveness Study (CACES)
To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD).
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Myelopathy, Compressive, Radiculopathy, Cervical Region
- Trial name
- CACES (NCT04623593)
- Testing
- ACDF, ACDA
- Where
- Netherlands
- Volunteers
- 198 people
- Sponsor
- Valérie Schuermans
Cervical Disc Herniation, Cervical Foraminal Stenosis
Endoscopic Posterior Cervical Foraminotomy Versus Anterior Cervical Discectomy and Fusion for Cervical Radiculopathy
Cervical radiculopathy caused by cervical disc herniation or foraminal stenosis is a common condition that may result in upper limb pain, sensory disturbances, and motor deficits.
- Conditions
- Cervical Disc Herniation, Cervical Foraminal Stenosis, Cervical Radiculopathy
- Trial name
- ENDOFOR (NCT07894159)
- Testing
- Uniportal Endoscopic Posterior Cervical Foraminotomy, Anterior Cervical Discectomy and Fusion
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Central Hospital, Nancy, France
Cervical Disc Herniation, Intervertebral Disc Displacement
Gelified Radiopaque Ethanol (Absolute Gel) in Cervical Disc Herniation: an Observational Study in Routine Clinical Practice (GENESIS)
GENESIS is a single-centre, observational, non-interventional, no-profit, investigator-initiated study conducted at Ospedale di Vimercate, ASST Brianza (Italy).
- Conditions
- Cervical Disc Herniation, Intervertebral Disc Displacement, Neck Pain, Chronic Pain
- Trial name
- GENESIS (NCT07832929)
- Testing
- Absolute Gel (radiopaque gelified ethanol)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Aurel Mengri
Low Back Pain, Neck Pain
Applying Artificial Intelligence in Developing Personalized and Sustainable Healthcare for Spinal Disorders
The primary objective is to use machine learning methods on large survey and health register data to identify participants with different treatment trajectories and health outcomes after surgical and/or conservative treatment for…
- Conditions
- Low Back Pain, Neck Pain, Disc Herniation, Disc Degeneration
- Trial name
- AID-Spine (NCT05745129)
- Where
- Norway
- Volunteers
- 165,000 people
- Sponsor
- Oslo Metropolitan University
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Cervical Disc Disease
Medium-Term Follow-Up of Alpha-D Cervical Disk Prosthesis
Prostheses use subsequently became prevalent and a number of studies were conducted. However, prosthesis-associated heterotropic ossification (HO) in the segments with prostheses was reported in 2005, which disrupted mobility and…
- Trial name
- NCT05262478
- Testing
- Alpha-D CDP
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Ataturk University
Degenerative Cervical Disc Disease
PRESTIGE Observational Study
Prestige artificial disc replacement is an alternative treatment option with 16 years of experience addressing the unmet needs of surgical fusion interventions.
- Trial name
- NCT00875810
- Where
- 26 sites in Czechia, Greece and 6 more
- Volunteers
- 194 people
- Sponsor
- Medtronic Spinal and Biologics
Cervical Degenerative Disc Disease
Post-Market Data Collection to Evaluate the Performance of the Synergy Disc®
This is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts.
- Trial name
- NCT06383962
- Testing
- Synergy cervical spine disc replacement
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Synergy Spine Solutions
Cervical Vertebral Disc Degeneration, Intervertebral Disc Displacement
Cervical Movement Control Before and After Anterior Cervical Discectomy and Fusion
Degenerative cervical disc disease can cause neck pain, nerve symptoms, dizziness, and problems with balance and head movement control.
- Trial name
- MOVE-ACDF (NCT07425613)
- Testing
- Anterior Cervical Discectomy and Fusion
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University of Ljubljana
Cervical Disc Disease
A Clinical Registry to Track the Real World Use of the Saber-C® Cervical Fusion Device
The objective of this registry study is to collect radiographic and clinical outcome measures to determine the effectiveness of the Saber-C device.
- Trial name
- NCT06240221
- Testing
- Elevation Spine Saber-C System
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Research Source
Cervical Radiculopathy, Cervical Disc Disease
Prospective Study of Fusion Rates Using Spira-C Device for Anterior Cervical Discectomy and Fusion Surgery
The objective of this study is to perform a prospective, single-arm clinical evaluation utilizing the Spira™-C 3-D printed titanium interbody device for treatment of degenerative disc disease and spinal stenosis of the cervical…
- Trial name
- ACDF (NCT03786432)
- Testing
- Spira-C Interbody Device
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Corewell Health East
Pain, Cervical Spinal Stenosis
KT® in Patients With Cervical Spine Surgery
Aim of the study was to investigate the effect of Kinesio taping application on upper trapezius muscle after cervical spine surgery.
- Conditions
- Pain, Cervical Spinal Stenosis, Disc, Herniated, Cervical Spondylosis
- Trial name
- NCT04039581
- Testing
- Kinesio Taping, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Radiculopathy, Musculoskeletal Diseases
Clinical Effectiveness of High-Intensity Laser Therapy in Patients With Cervical Radiculopathy:
This investigation aims to investigate the effect of high intensity laser therapy on radicular symptoms, neuropathic pain, cervical range of motion and quality of life in patients with cervical radiculopathy compared to cervical…
- Conditions
- Radiculopathy, Musculoskeletal Diseases, Cervical Pain, Cervical Radicular Pain
- Trial name
- NCT04734977
- Testing
- High-intensity laser therapy (HILT), Therapeutic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Afyonkarahisar Health Sciences University