Clinical trials: Cervical Spine Disease
Disc Degeneration
Low Level Lazer Therapy Effect on Vertebral Artery Blood Flow in Elderly With Cervical Disc Degeneration
This study will include 60 elderly patients with cervical disc degeneration, from both gender who are aged from 60 - 75 years old.
- Trial name
- NCT06025175
- Testing
- Low level Lazer therapy, Routine exercises
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Neck Pain, Cervical Spondylosis
Radiofrequency Plus Superficial Cervical Plexus Block in Treatment of Cervical Spondylosis Pain
The goal of this clinical trial is to compare the effectiveness in the pain relief between doing radiofrequency ablation for the medial branch of the cervical facet pain alone vs using it combined with superficial cervical plexus…
- Trial name
- NCT06480175
- Testing
- cervical plexus block
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams University
Symptomatic Cervical Disc Disease
Performance of the Hedrocel(R) Cervical Fusion Device
The objective of this clinical investigation is to compare patients treated with Anterior Cervical Discectomy and Fusion (ACDF) using the Hedrocel Cervical Fusion Device, with a concurrent, randomized, control group receiving…
- Trial name
- NCT00758758
- Testing
- Anterior Cervical Discectomy and Fusion
- Where
- 13 sites in United States
- Volunteers
- 231 people
- Sponsor
- Zimmer Biomet
Back Pain, Neck Pain
Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain
HYPTHOTHESIS: The researchers hypothesize that application of active magnetic therapy vs. sham utilized while individuals sleep can reduce neuropathic pain in the spine and improve the quality of sleep.
- Conditions
- Back Pain, Neck Pain, Sleep Initiation and Maintenance Disorders
- Trial name
- SLEEP/MAG (NCT00445133)
- Testing
- Magnetic Sleep Pad
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Weintraub, Michael I., MD, FACP, FAAN
Motor Imagery, Neck Pain
Motor Imagery Ability and Cervical Discogenic Pain
Background: The purpose of the study was to examine the motor imagery ability and its association with pain, functional status, neck awareness and depression levels in individuals with cervical discogenic pain (CDP).
- Conditions
- Motor Imagery, Neck Pain, Disc Herniation, Functional Status
- Trial name
- NCT06502236
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Thyroid, Surgery
A Deep Learning Method to Predict Difficult Laryngoscopy Using Cervical Spine X-ray Image
An unanticipated difficult laryngoscopy is associated with serious airway-related complications. The investigators developed a deep learning-based model that predicts a difficult laryngoscopy (Cormack-Lehane grade 3-4) from a…
- Conditions
- Thyroid, Surgery, Intubation; Difficult or Failed
- Trial name
- NCT05176184
- Testing
- A deep learning model for predicting a difficult laryngoscopy based on a cervical spine lateral X-ray image
- Where
- South Korea
- Volunteers
- 367 people
- Sponsor
- Seoul National University Hospital
Osteoporosis (Senile)
To Study the Efficacy and Safety of Doxercalciferol on Spinal and Femoral Density in Postmenopausal Osteopenic Women in a Long Term 2 Year Study
A clinical trial to compare the effect of doxercalciferol or placebo in preventing bone loss from the spine and femur in postmenopausal women
- Trial name
- NCT07660536
- Testing
- doxercalciferol capsules, Hectorol®
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Creighton University
Cervicogenic Headache
Effects of ELDOA in Patients With Cervicogenic Headache
The aim of our study is to determine the effect of ELDOA in relieving pain, improving ROM and functional disability in patients with cervicogenic headache.
- Trial name
- NCT06377787
- Testing
- ELDOA and conventional therapy, conventional therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Cervical Spine Disease
Positional Release Technique in Patients With Unilateral Subacute Trapezitis
To assess the effects of positional release technique to improve the cervical range of motion, relieve pain and function in the patient with unilateral subacute trapezitis.
- Trial name
- NCT04716192
- Testing
- Positional release technique, Myofascial release technique & Ultrasound
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Degenerative Disc Disease
Interbody Systems: Post Market Clinical Follow-up Study
This is a prospective, multi-center study of subjects who will undergo spinal fusion surgery utilizing Stryker Interbody Systems that require post market clinical follow up (PMCF).
- Trial name
- NCT04911257
- Testing
- Cervical or Lumbar Spinal fusion
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- K2M, Inc.
Airway Obstruction
Supraglottic Airways for Entrapped Trauma Patients
The aim of this clinical trial is to evaluate four supraglottic airway devices for ventilation in a simulated condition of an entrapped trauma patient with simultaneous cervical spine immobilisation.
- Trial name
- NCT06545903
- Testing
- LMA Supreme, SLIPA, I-gel
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Uniwersytet Radomski im. Kazimierza Pułaskiego
Lumbar Degenerative Disc Disease, Cervical Degenerative Disc Disease
Evaluation of the Prosthetic Disc Replacement
Until now, arthrodesis (intervertebral fusion) is the formal treatment for the lumbar and cervical degenerative disc disease : arthrodesis has been the standard surgical treatment for the patients when nonsurgical management has…
- Conditions
- Lumbar Degenerative Disc Disease, Cervical Degenerative Disc Disease, Kyphosis
- Trial name
- EVA (NCT00640029)
- Testing
- Arthrodesis, Arthroplasty (PRODISC-C® , PRODISC-L®, Mobi-C®, Mobidisc®, PrestigeLP®, A-Mav®, O-Mav®, DISCOCERV®)
- Where
- 2 sites in France
- Volunteers
- 301 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ossification of the Posterior Longitudinal Ligament
A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossification of the Posterior Longitudinal Ligament With High Occupation Rate in Cervical Spine
The efficacy of laminoplasty and laminectomy with fusion for ossification of the posterior longitudinal ligament with high occupation rate in the cervical spine is not clear in the literature report so far.
- Trial name
- NCT05019001
- Testing
- Laminoplasty, Laminectomy With Fusion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Spinal Stenosis Cervical
Multicentric Case Series of Uniportal Endoscopic Posterior Cervical Decompression for Cervical Spinal Stenosis
Cervical spinal stenosis is a condition that can cause pain, sensory disturbances, and motor deficits due to the compression of neural structures in the cervical spine.
- Trial name
- DEC-SCM (NCT06886802)
- Testing
- Posterior Uniportal Endoscopic Cervical Decompression
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- TecSalud Investigación Clínica
Dysphagia
Dysphagia Following Anterior Cervical Spine Surgery; Steroid vs Saline
This prospective, randomized, double blind, controlled study evaluates the effect of perioperative IV steroids versus saline on swallowing after anterior cervical spine surgery.
- Trial name
- DysDexVSSal (NCT02416934)
- Testing
- Treatment 1; Dexamethasone
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Intervertebral Disc Degeneration
Safety and Performance of the SPINEVISION Hexanium ACIF in the Treatment of Cervical Spine Degenerative Disc Disease
The goal of this observational study is to confirm the safety and efficacy of the Hexanium ACIF system in the treatment of skeletally mature patients suffering from degenerative disc disease (disease that occurs when the spinal…
- Trial name
- NCT06155409
- Testing
- Anterior cervical interbody fusion
- Where
- 6 sites in France
- Volunteers
- 148 people
- Sponsor
- SPINEVISION SAS
Posterior Cervical Decompression and Fusion
A Randomized Controlled Crossover Study Comparing Sugammadex and Placebo
Intraoperative monitoring of the motor evoked potentials has been shown to be both a sensitive and specific indicator for detecting intraoperative neurological injuries during spine surgery.(Fehlings, Brodke et al.
- Trial name
- NCT03087513
- Testing
- Sugammadex Injection [Bridion]
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Cervical Stenosis, Disk, Herniated
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we…
- Conditions
- Cervical Stenosis, Disk, Herniated, Spondylosis
- Trial name
- NCT05356286
- Testing
- epidural electrical stimulation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II)
Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.
This study is an open-label study to determine the feasibility of Motor Cortex Stimulation (MCS) in the treatment of patients with chronic pain of the face or upper extremity.
- Conditions
- Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II), Trigeminal Neuropathic Pain, Trigeminal Deafferentation Pain
- Trial name
- NCT02321566
- Testing
- Epidural Motor Cortex Stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Spinal Stenosis Cervical, Radiculopathy, Cervical Region
Hard Cervical Collar Use Following Posterior Cervical Fusion
Postoperative immobilization with a hard cervical collar following posterior cervical fusion remains common practice despite limited evidence demonstrating improved clinical outcomes.
- Conditions
- Spinal Stenosis Cervical, Radiculopathy, Cervical Region, Posterior Cervical Fusion, Spondylosis, Cervical
- Trial name
- NCT07789288
- Testing
- Hard Cervical Collar
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Georgetown University