Clinical trials: Cervix
Gonorrhea, Gonorrhea of Pharynx
BIYELA - Bexsero Immunisation in Young Women in Africa
This proposed 2-arm randomized evaluation of two doses of 4CMenB vaccine versus placebo at Enrollment and Month 2 is designed as a proof-of-concept study to inform potential use for dual meningococcal B and gonococcal prevention…
- Conditions
- Gonorrhea, Gonorrhea of Pharynx, Gonorrhea of Anus, Gonorrhea of Cervix
- Trial name
- NCT06446752
- Testing
- Bexsero
- Where
- 5 sites in South Africa
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain With Paracervical Block, Pain With Gynecology Procedure
Applying Num Vapocoolant Spray to Cervix Before Paracervical Block to Decrease Pain During Gynecology Procedures
The purpose of this study is to assess if Num vapocoolant spray decreases pain associated with paracervical block in gynecology procedures.
- Conditions
- Pain With Paracervical Block, Pain With Gynecology Procedure, Pain
- Trial name
- VAPOR (NCT06227052)
- Testing
- Num Vapocoolant Spray
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Queen's Medical Center
Cervix
Cervical Recuperation After Vaginal Delivery
Patients after vaginal delivery will undergo 3 trans-vaginal ultrasounds in order to examine the process of cervical recuperation post delivery.
- Trial name
- NCT03034434
- Testing
- Trans-vaginal ultrasound
- Where
- Israel
- Volunteers
- 1,384 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cancer Cervix
Carrying Out of Focus Group to Improve Cervical Screening Proposal by Vaginal Self-sampling (APACHE-4/FG).
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-4/FG (NCT03420157)
- Testing
- Focus Group
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Cervix Cancer, Cervix Lesion
Honduras Liger Thermocoagulator Study
This was a prospective study to evaluate the short-term safety and acceptability of the Liger Medical thermal coagulation device for treatment of cervical precancerous lesions.
- Trial name
- NCT03510273
- Testing
- Liger Medical Thermocoagulator
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- PATH
Benign Neoplasm of Cervix Uteri, Gynecological Laparoscopy
The Effects of CO2 Pneumoperitoneum at Different Temperature in Laparoscopic Surgery
Objective: It is recommended to heat and humidify CO2 in laparoscopic surgery to prevent postoperative pain and hypothermia but information about its effects on hemodynamic and respiratory parameters is limited.
- Trial name
- NCT04508387
- Testing
- Group HH (heated-humidified)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Human Papillomavirus Infection, Self Sampling
HPV Typing Between Self- and Physician-sampled
Hygeia Touch Inc. developed a safe and comfortable vaginal self-sampling device "Hygeia Touch Self Sampling Kit for Women" to self-collect the vaginal discharge sample for high-risk Human Papillomavirus (hrHPV) detection.
- Conditions
- Human Papillomavirus Infection, Self Sampling, Vaginal Discharge
- Trial name
- NCT04472377
- Testing
- Self sampling kit for collecting discharge from vaginal fornix
- Where
- 3 sites in Taiwan
- Volunteers
- 1,210 people, healthy volunteers welcome
- Sponsor
- Hygeia Touch Inc.
Preterm Birth, Twin Pregnancy, Antepartum Condition or Complication
Prophylactic Cervical Cerclage in Twin Pregnancies With Non-shortened Cervix
This randomized controlled trial is aimed to assess the protective value of prophylactic cervical cerclage against preterm birth in twin pregnancies with history of one or more preterm births without having cervical shortening in…
- Conditions
- Preterm Birth, Twin Pregnancy, Antepartum Condition or Complication, Cervical Cerclage
- Trial name
- NCT05334264
- Testing
- Cervical cerclage
- Where
- Egypt
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cervix; Pregnancy, Inherited Genetic Conditions (Diagnosis)
Optimization of Cervical Collections in Pregnancy
Fetal cells are not easily obtained from pregnant patients; this curtails testing to assess the health of the fetus and the mother.
- Conditions
- Cervix; Pregnancy, Inherited Genetic Conditions (Diagnosis), Preeclampsia, Fetal Growth Retardation
- Trial name
- OCCP (NCT06323187)
- Testing
- Cervical Sampling
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Dr. Sascha Drewlo
Unfavorable Cervix, Cervical Ripening
Combined Foley Catheter Balloon and PGE2 Vaginal Ovule for Induction of Labor at Term: A Randomized Study
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 in induction of labor at term.
- Trial name
- NCT02861079
- Testing
- Foley catheter, PGE2
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Healthy
Phase I Study of HAL Formulations Applied to the Cervix in Healthy Volunteers
The purpose of the study is to determine the most effective formulation of HAL for release of hexaminolevulinate to the cervical epithelium at different doses.
- Trial name
- NCT00496171
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- Photocure
Tracheostomy Complication, Emergency Front of Neck Airway in Children
Neck Rescue Access Comparison
Emergency front-of-neck access (eFONA) represents the final lifesaving intervention in a pediatric "can't intubate, can't oxygenate" scenario.
- Conditions
- Tracheostomy Complication, Emergency Front of Neck Airway in Children, Anesthesia
- Trial name
- eFONA (NCT07368179)
- Testing
- Percutaneous Seldinger-Guided Tracheal Access (Melker), scalpel-bougie tracheostomy
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Premature Birth
LATe Cerclage in High-risk Pregnancies (LATCH)
The goal of this clinical trial is to determine whether cervical cerclage reduces the risk of preterm birth in patients with a short transvaginal ultrasound (TVU) cervical length (CL) ≤25mm between 24 0/7-26 6/7 weeks.
- Trial name
- LATCH (NCT06036446)
- Testing
- Cervical cerclage, Vaginal Suppository Progesterone
- Where
- 2 sites in United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cervical Pain, Pelvic Pain
Tenaculum Pain Control Study
The purpose of this clinical trial is to evaluate the effect of an intracervical lidocaine injection versus topical lidocaine gel on the pain experienced by patients undergoing tenaculum application to the cervix during office…
- Trial name
- NCT01421641
- Testing
- Intracervical Lidocaine Injection, Topical Lidocaine Gel
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cervix Cancer
Prevalence of Abnormal Pap Smear
This study aims to evaluate prevalence of abnormal Pap smear among sexually active women of reproductive age attending sohag university hospital outpatient clinic.
- Trial name
- NCT06641531
- Testing
- Screening pap smear test
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cancer of the Cervix, Cervical Intraepithelial Neoplasia
Compass - Randomised Controlled Trial of Primary HPV Testing for Cervical Screening in Australia
Compass is a randomised controlled trial of primary HPV testing for cervical cancer screening in Australia. A pilot study involving 5,000 women was carried out in 2013-2014.
- Trial name
- Compass (NCT02328872)
- Testing
- Molecular testing for HPV, Liquid Based Cytology
- Where
- Australia
- Volunteers
- 76,181 people, healthy volunteers welcome
- Sponsor
- VCS Foundation
Short Cervix, PROM, Preterm (Pregnancy)
Microbiological and Biochemical Profiling of Amniotic Fluid in Women With Short Cervix or Premature Rupture of Membranes
This study aims at assessing the efficacy, reliability, and clinical impact of Amniotic Fluid analysis by Nanopore DNA sequencing compared to the standard bacterial cultures in detecting intra-amniotic/inflammation in patients…
- Trial name
- CIPRO (NCT07792083)
- Testing
- amniotic fluid collection
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
HPV Infections, Precancerous Disease of the Cervix
Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China
In a hospital-based multi-center study in China, HPV 16 was found to be the predominant type (72.9%) in cervical cancer, followed by HPV 18(8.0%) which indicated that if the HPV prophylactic vaccine are wisely applied in China…
- Conditions
- HPV Infections, Precancerous Disease of the Cervix, Cervical Cancer, HPV Related Diseases
- Trial name
- NCT01021904
- Testing
- Gardasil (VLP, HPV Quadrivalent prophylactic vaccine)
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Unexpected Difficult Airway
Increase Residents' Confidence in Emergency Front of Neck Access (eFONA).
Emergency front of neck access (eFONA) in a non-ventilated, non-oxygenated (CVCO) patient scenario is a life-saving and important competency for anesthesiologists to learn and even repeat intermittently.
- Trial name
- NCT06491147
- Testing
- Emergency front of neck access
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Outpatient Mechanical Cervix Priming
Outpatient Foley Cervix Priming
The aim was to conduct a non-blinded prospective randomized study at a tertiary hospital. Inclusion criteria: term pregnancy with a single fetus in cephalic presentation, Bishop score < 6, gestational age > 41 weeks or medical…
- Trial name
- NCT02842879
- Testing
- Outpatient Foley cervix priming
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital de Santa Maria, Portugal