Clinical trials: Cervix Lesion
Cervix Lesion, Cervical Cancer
Application of Plasma Circulating HPV DNA Testing to Management of Cervical Intraepithelial Neoplasia
The purpose of this study is to see if circulating HPV DNA (cHPVDNA) can be used as a noninvasive biomarker for cervical intraepithelial neoplasia (CIN) 2-3 in hopes of reducing procedures and costs for patients, as well as…
- Trial name
- NCT04274465
- Testing
- digital PCR (dPCR) assay
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG
Desensitizing Effect and Tooth Color Change After Using Giomer-based Varnish Versus Bioactive Glass Air Polishing in Treating Cervical Hypersensitive Lesions
This trial is test the dentin hypersenstivity using Giomer based Varnish versus Bioactive glass air polishing system in patients with non-cervical lesions.
- Trial name
- NCT05981625
- Testing
- Giomer varnish containing surface pre-reacted glass fillers
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
CAF With or Without CTG for the Treatment of Single Maxillary Gingival Recession With NCCL
This studies evaluate the efficacy of the coronally advanced flap (CAF) with or without connective tissue graft (CTG) for the treatment of single maxillary recession associated to non carious cervical lesion (NCCL).
- Trial name
- NCT03862534
- Testing
- CAF, CAF + CTG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florence
Gingival Recession
Two Surgical Approaches for Root Coverage of Teeth Presenting Gingival Recession and Non-carious Cervical Lesion
The aim of the present study is to compare the use of the xenogeneic graft (MC) plus coronary advanced flap (CAF) and the coronary advanced flap alone, both associated with the partial restoration of composite resin in the…
- Trial name
- NCT03341598
- Testing
- CAF, R, MC
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Hypersensitivity Dentin, Tooth Hypersensitivity
Effectiveness of Bioactiveglass Air Abrasion Versus Fluoride Varnish in Management of Dentin Hypersensitivity
Will the use of Bioactive glass with air abrasion technology (Sylc) compared to Fluoride Varnish (Biflourid 10) affects the degree of pain in patients complaining from hypersensitivity due to non-carious lesions?
- Trial name
- NCT03285360
- Testing
- Sylc, fluoride varnish (Bifluorid 10)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Retraction
Subgingival Clamp Versus Retraction Cord in Cervical Lesions in Term of Technique Sensitivity and Gingival Health
assessing subgingival clamp in handling and retracting the gingival tissue at the cervical area to see its effect on the gingival health and its technique sensitivity compared to the most commonly used method (retraction cord)…
- Trial name
- NCT03917108
- Testing
- retraction cord, subgingival clamp
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non Carious Cervical Lesion
Effect of an Additional Hydrophobic Adhesive Layer Application on the Class V Composite Restorations
In restorative dentistry, to enhance bond strength between dentin and simplified adhesive systems, new materials or applications are constantly being developed all the time.
- Trial name
- NCT05635981
- Testing
- Clearfil Majesty ES-2 Resin Composit Application to Non-carious Cervical Lesions
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dentin Hypersensitivity
Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration, Dentin Bonding, and Clinical Durability of Composite Restorations.
This study will investigate the efficacy of three diode laser wavelengths 445 nm, 660 nm, 970 nm when applied just before placement of composite restoration on reducing postoperative sensitivity from Non-carious cervical lesions…
- Trial name
- NCT05501691
- Testing
- 445 nm Diode Laser Wavelength, 660 nm Diode Laser Wavelength, 970 nm Diode Laser Wavelength
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Healthy Participant
Different Modes of Universal Adhesive in Smokers and Non-Smokers
The aim of the study was to evaluate the influence of smoking on the clinical performance of a universal adhesive used with different application modes in non-carious cervical lesions.
- Trial name
- NCT04807465
- Testing
- G-Premio Bond in etch&rinse mode, G-Premio Bond in selective-etch mode, G-Premio Bond in self-etch mode
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dentin Sensitivity, Hypersensitivity
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects".
- Conditions
- Dentin Sensitivity, Hypersensitivity, Cervical Lesion
- Trial name
- NCT06463938
- Testing
- Active comparator, Experimental group, Combination of laser and paste
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Noncarious Cervical Lesions
Clinical Evaluation of Four Aesthetic Restorations in Non-carious Cervical Lesions
To compare the clinical performance of high-viscosity glass ionomer, flowable composite, bulkfill composite and nanohybrid composite restorations in non-carious cervical lesions (NCCLs).
- Trial name
- NCT04261140
- Testing
- EQUIA Forte Fil, Clearfil Majesty Esthetic, NexComp Flow
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Non-carious Cervical Lesions
Effect of Wet and Overwet Dentin on the Clinical Performance of Two Universal Adhesive Systems
The aim of this study will be to evaluate the effect of wet and overwet dentin on the long-term clinical performance of two universal adhesive systems used as etch-and-rinse application mode in non-carious cervical lesions…
- Trial name
- NCT07034235
- Testing
- Dentin Wet, Dentin Overwet, Ambar Universal APS Plus; FGM
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Non-carious Cervical Lesions
Release of Organic Components of a GIOMER in Non-carious Cervical Lesion Restorations
To evaluated the clinical performance of composite resin restorations, considering also the evaluation of release of resin components into saliva and the presence cytokines in gingival fluid.
- Trial name
- NCT03637946
- Testing
- Device: SHOFU beautifil II LS
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Non-Carious Cervical Lesions
36-Month Clinical Evaluation of a Universal Adhesive
The aim of this clinical trial was to evaluate and compare the performance of a universal adhesive with different adhesive strategies in the restoration of non-carious cervical lesions (NCCLs) over a 36-month period.
- Trial name
- NCT03932929
- Testing
- Scotchbond Universal Adhesive (3M ESPE)
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Participant
Laser Etching Effect on Application Mode of Universal Adhesive
To evaluate the clinical performance of the restorations by applying the universal adhesive in different modes under the influence of different surface treatments, with Erbium Chromium:Yttrium-Scandium-Gallium-Garnet (Er,Cr:YSGG)…
- Trial name
- NCT04814836
- Testing
- Total-etch mode with 35% phosphoric acid (K-ETCHANT) (TE-A group), Selective-etch mode with 35% phosphoric acid (K-ETCHANT) (SE-A group), Total-etch mode with Er, Cr: YSGG laser (Waterlase MD) (TE-L group)
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Non-carious Cervical Lesions
Deproteinization as a Coadjuvant in Dentin Adhesion of Noncarious Cervical Lesions
This study will verify the effect of the application of a substance (10% sodium hypoclorite -NaOCL) in dentin on noncarious cervical lesions, with the aim of increasing the longevity of the restorations performed in this type of…
- Trial name
- NCT03086720
- Testing
- Sodium hypochlorite, Water
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Retention
Restoration of Non-carious Cervical Lesions With Different Resin Composites and Universal Adhesive
patients with non carious cervical lesions suffer from dentin sensitivity and presence of cavitations and gingival recession. Restoring these lesions with different composites and evaluation of restorations every 6 months will be…
- Trial name
- NCT06393699
- Testing
- composite restoration
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Class V Non-carious Cervical Dental Lesions
Impact of Dentin Pretreatment With Dimethyl Sulfoxide on Behavior of Resin Composite Restorations in Non-Carious Cervical Lesions
the aim of this study to evaluate and compare the impact of dimethyl sulfoxide dentin surface pretreatment on the performance of composite restorations in non-cervical carious lesions
- Trial name
- NCT07830641
- Testing
- Dimethyl sulfoxide (DMSO), NO dimethyl sulfoxide
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Non Carious Cervical Lesion, Gingival Recessions
Association Between Periodontal Morphology and Non-Carious Cervical Lesions
This observational study aims to investigate the relationship between periodontal morphology, oral hygiene habits, and non-carious cervical lesions (NCCLs) in adults aged 18-65 years.
- Trial name
- NCCL-PM (NCT07629492)
- Testing
- Periodontal Examination and Oral Habit Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Cervical Lesion
Bioactive Restorative Material in Non-Carious Cervical Lesions
Evaluating the clinical performance of a bioactive restorative materiel (Cention N) placed in non-carious cervical lesions (NCCLs) with no preparation and 1-step adhesive system or, with preparing a gingival retentive groove and…
- Trial name
- NCT05593159
- Testing
- Dentin Conditioning, RM-GIC, 1-step adhesive
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University