Clinical trials: Cesarean Section; Infection
Urinary Tract Infections, Cesarean Section; Infection
Caesarean Delivery With or Without an Indwelling Bladder Catheter
The aim of this study is to compare the incidence of catheter associated culture-based urinary tract infection (UTI) after elective CD with or without preoperative placement of a urinary catheter.
- Trial name
- NCT03672214
- Testing
- Without placement of indwelling catheter, With placement of indwelling catheter
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Endometritis, Wound Infection
Timing of Prophylactic Antibiotics for Cesarean Sections
This is a randomized, double-blinded placebo controlled trial of cefazolin timing before cesarean section fo infection prophylaxis.
- Trial name
- NCT00330278
- Testing
- Cefazolin
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Elective Cesarean Section
Antibiotic Prophylaxis Before Surgery Versus After Cord Clamping in Elective Cesarean Delivery - a Double-blind, Prospective, Randomized Placebo-controlled Trial
In this prospective, randomized, placebo controlled trial the investigators were able to demonstrate the usefulness of prophylactic cefazolin in elective caesarean section versus placebo, irrespective of the timing of…
- Trial name
- NCT01248078
- Testing
- Keflex, saline solution
- Where
- Austria
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Infection; Cesarean Section
Betadine Irrigation in Cesarean Section
The purpose of this study was to evaluate, for the first time in Literature, the effects of betadine washing versus normal saline washing after uterine closure in women undergoing cesarean section (CS) at ≥36 gestational weeks in…
- Trial name
- NCT02865993
- Testing
- betadine group, no betadine group
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Cesarean Section; Infection
Subcuticular Skin Closure at Cesarean Delivery
Subcuticular skin closure with suture after cesarean has been shown to result in lower rates of wound complications than with staple closure.
- Trial name
- NCT03536832
- Testing
- Cesarean Section with Vicryl, Cesarean Section with Prolen
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cesarean Section; Infection, Scar
Evaluation of Wound Infection Rates and Cosmetic Results of Different Suture Materials in Cesarean Skin Incision
Our primary aim is to determine the most beneficial suture in order to reduce complications due to skin incision in common surgeries such as cesarean section, and our secondary aim is to evaluate the suture material used in terms…
- Trial name
- NCT06119113
- Testing
- Evaluation of the wound infection at the 10th day post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 2nd month post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 6th month post-op check-up among all groups
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ayşenur Çalış Özbayram
Surgical Wound Infection
Alexis O-Ring Wound Retractor for the Prevention of Post-cesarean Surgical Site Infections
Post cesarean section surgical site infection (SSI) is a common complication that can affect patient recovery and overall outcome.
- Trial name
- Alexis (NCT03365219)
- Testing
- Alexis O-Ring Wound Retractor, Standard Surgical Retractors
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Nausea, Vomiting
Intra-abdominal at Cesarean Section: A Randomized Controlled Trial
The purpose of this study is to determine if intra-abdominal irrigation at the time of cesarean delivery increased maternal GI discomfort without affecting infection rates.
- Trial name
- NCT01479712
- Testing
- Normal Saline Irrigation
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Incidence of cs Scar Infection
Normal Saline Versus Betadine Use to Reduce the Incidence of Wound Infection in Cesarean Section
This is a prospective randomized controlled study to the difference between using normal saline or betadine irrigation of wound prior to skin closure in reducing the incidence of wound infection after Cesarean section.
- Trial name
- NCT03725748
- Testing
- irrigation
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Obesity, Wound Infection
Kerlix for Pregnant Women With Elevated BMI to Prevent Wound Infection by 6 Weeks Post Partum
Pregnant women with BMI>40 will be approached for participation in a study to reduce the rate of post-operative wound infection from C-section.
- Conditions
- Obesity, Wound Infection, Pregnancy
- Trial name
- NCT02882360
- Testing
- Kerlix-AMD
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Complications; Cesarean Section
Vaginal Cleansing Before Cesarean Delivery to Reduce Infection
The purpose of this study is to test the hypothesis that vaginal cleansing with povidone-iodine solution immediately prior to cesarean delivery reduces postcesarean infectious morbidity.
- Trial name
- NCT02495753
- Testing
- Vaginal Cleansing, Abdominal Cleansing
- Where
- United States
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Surgical Site Infection, Cesarean Section; Infection
Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections
This will be a single-center randomized control trial comparing the efficacy of two different formulations of Chlorhexidine surgical skin preparation in preventing cesarean section wound infections.
- Trial name
- NCT05920122
- Testing
- 2% Chlorhexidine gluconate with 70% alcohol, 4% Chlorhexidine Gluconate aqueous solution
- Where
- United States
- Volunteers
- 1,398 people, healthy volunteers welcome
- Sponsor
- Hyagriv Simhan
HIV Infections
Blood Levels of Tenofovir Gel in HIV Uninfected Pregnant Women Planning Cesarean Delivery
A new approach to HIV prevention currently being studied includes the use of topical microbicides, substances that kill microbes.
- Trial name
- NCT00540605
- Testing
- Tenofovir 1% vaginal gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cesarean Section Complications
Clean-CS: A Program to Improve the Safety of C-section
Executive summary: Cesarean delivery, or section (CS), is the single most common surgical procedure performed. Estimates indicate that in low resource settings, CS comprises up to 50% of more of the total volume of operations…
- Trial name
- Clean-CS (NCT04812522)
- Testing
- Clean Cut program
- Where
- 10 sites in Ethiopia
- Volunteers
- 10,506 people, healthy volunteers welcome
- Sponsor
- The Lifebox Foundation
Surgical Site Infection
Chlorhexidine Cloths to Reduce Surgical Site Infection in Cesarean Deliveries
Pregnancy-associated infection represents a major cause of maternal morbidity and mortality. Cesarean delivery is the most common major surgical procedure and is associated with a rate of surgical site infection (SSI) that is…
- Trial name
- NCT04202471
- Testing
- Chlorhexidine Cloth
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Cesarean Section
Sharp Versus Blunt Fascial Incision at Caesarean Section
The purpose of this study is to compare sharp and blunt fascial entry during caesarean section on the same patient. The study is performed on woman having cesarean section for the first time and who have not previously had lower…
- Trial name
- NCT01297725
- Testing
- Blunt right, sharp left, Blunt left, sharp right
- Where
- 2 sites in Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
C-Section
Influence of Probiotics on Early Gut Microbial Colonization
The goal of this clinical trial is to learn whether daily probiotic drops plus vitamin D3 can improve early gut microbiome colonization in healthy infants born by C-section. It will also assess safety and tolerability.
- Trial name
- STORKIE (NCT07608341)
- Testing
- Probiotic drops
- Where
- 2 sites in Finland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Surgical Site Infection
Using mHealth Technology to Identify and Refer Surgical Site Infections in Rwanda
The present study aims to examine whether or not the use of mobile Health (mHealth) by community health workers (CHWs) can improve the identification of surgical site infection (SSI) and a timely return to care among patients who…
- Trial name
- NCT03311399
- Testing
- SSI Screening Tool used in home visits by CHWs, SSI Screening Tool used via phone call follow-up
- Where
- Rwanda
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Surgical Site Infection
The Mepilex Cesarean Delivery Trial / MEPIDEL
The goal of this clinical trial is to learn whether a silver-containing foam dressing (Mepilex Border Post-Op Ag) works as well as the standard dressing in preventing surgical site infection after cesarean delivery.
- Trial name
- MEPIDEL (NCT07914569)
- Testing
- Mepilex Border Post-Op Ag, Standard Postoperative Dressing
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center