Clinical trials: Cesarean Section Rate
Anesthesia, Spinal, Anesthesia, Obstetrical
The Effect of Injection Rate of Local Anesthetic in Caesarean Section
This randomized double-blind study aimed to compare the effects of two different subaracnoid lokal anesthetic injection rate in cesarean section. Totally 67 patients were included.
- Trial name
- NCT05091294
- Testing
- Local anesthetic injection rate in spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pregnancy, Prolonged
Propranolol Rescue of Prolonged Labor
A double-blind placebo controlled randomized trial comparing cesarean delivery rates in women given IV propranolol versus placebo for treatment of prolonged labor.
- Trial name
- PROPEL (NCT04299438)
- Testing
- Propranolol Hydrochloride, Saline
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Lisa Levine
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labor, Obstetric, Pregnancy
Obstetric Risk Assessment & Cesarean-delivery in Labor Estimation Using Artificial Intelligence
ORACLE-AI is a single-center, open-label, randomized clinical trial comparing primiparous women managed with a real-time machine-learning dashboard against a concurrent control group receiving standard intrapartum care.
- Conditions
- Labor, Obstetric, Pregnancy, Cesarean Section Rate
- Trial name
- ORACLE-AI (NCT07430358)
- Testing
- Software-based, real-time AI dashboard providing continuous risk estimates for unplanned cesarean delivery during labor.
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Healthy Participants
Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.
Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy…
- Trial name
- RateTXA (NCT06356948)
- Testing
- Tranexamic Acid (TXA)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cesarean Section Complications, Hemodynamic Instability
Impact of Carbetocin Administration on Heart Rate When Given as an Infusion Versus as a Bolus.
Prospective, randomized and controlled study who will be conducted at Maisonneuve-Rosemont hospital with the following objectives: To determine if an infusion of carbetocin over 10 minutes will reduce hemodynamic side effects…
- Trial name
- NCT03404544
- Testing
- Carbetocin bolus, Carbetocin infusion
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Gastric Emptying, Pregnancy
Rate of Gastric Emptying in Term Parturients Undergoing Elective Cesarean Section
The aim of the study is to use sequential ultrasound evaluation of the gastric volume to determine how long it takes for the stomach of a fasting pregnant woman at term, admitted for elective cesarean section, to empty after…
- Trial name
- NCT03800251
- Testing
- Nutricia PreOp - a clear, non-carbonated, lemon flavoured, carbohydrate drink that provides 0.5kcal/ml
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Pregnancy
Hydration and Rate of Cesarean Delivery Among Nulliparous
The hypothesis of the present study is the hydration of nulliparous women with 250ml/hour vs. 125ml/hrs would decrease the rate of primary cesarean section.
- Trial name
- NCT01944787
- Testing
- Routine, IV Hydration at 250cc hour
- Where
- United States
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Chauhan, Suneet P., M.D.
Spinal Induced Hypotension in Cesarean Delivery
Up-Down Determination of the ED90 of Phenylephrine for Hypotension Prophylaxis in Cesarean Delivery
This study is designed to determine the ED90 for an infusion of phenylephrine to prevent spinal induced low blood pressure in parturients presenting for an elective cesarean delivery.
- Trial name
- NCT00796328
- Testing
- Phenylephrine infusion
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Anesthetic Complication Spinal
Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Rapid administration of crystalloid immediately after induction of spinal anesthesia (coload) to be more effective in terms of managing hypotension as compared to administering crystalloid before spinal anesthesia (preload).
- Trial name
- NCT01378325
- Testing
- Phenylephrine, saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Caesarean Section, Pregnant Women
Effects of Acupressure Applied Before Cesarean Delivery on Anxiety, Physiological Parameters and Fetal Heart Rate
Cesarean section is the most commonly preferred surgical method in cases where vaginal birth is not possible or complications that may endanger the health of the mother and baby occur.
- Conditions
- Caesarean Section, Pregnant Women, Anxiety Disorder
- Trial name
- NCT06953037
- Testing
- acupressure
- Where
- 2 sites in Cyprus
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Continuous Fetal Heart Beat Monitor and Analysis After Spinal Anesthesia
Fetal Heart Rate Pattern After Spinal Anesthesia for Scheduled Uncomplicated Cesarean Section
Spinal anesthesia may cause sympathetic blockade which decrease peripheral vascular resistance and bradycardia and then hypotension.
- Trial name
- NCT05776186
- Testing
- Spinal anesthesia with heavy bupivacaine
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Mode of Delivery, Pelvic Floor Dysfunction
A RCT to Evaluate the Effects of Pelvic and Abdominal Mechanical Exercises During Pregnancy on Reducing the Rate of CS and Preventing PFD
Pelvic floor dysfunction diseases seriously affect the quality of life. Childbirth, especially vaginal birth, is significantly related to pelvic floor dysfunction diseases, which mainly cause urinary incontinence and pelvic organ…
- Trial name
- NCT05252455
- Testing
- pelvic and abdominal mechanics exercise
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Qiu Jin
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cesarean Section Rate
Evaluation of the Hem-Avert® Perianal Stabilizer Into Routine Clinical Practice
This is a retrospective data-only study following the phased introduction of the HEM-AVERT® Perianal Stabilizer into routine clinical practice.
- Trial name
- NCT02562547
- Testing
- Hem-Avert Perianal Stabilizer
- Volunteers
- 799 people, healthy volunteers welcome
- Sponsor
- Desert Perinatal Associates
Cesarean Delivery Affecting Fetus or Newborn
Routine Maternal Leg Movements During the Second Stage and the Rate of Operative Deliveries
Cesarean delivery rates have risen in the US in a dramatic fashion from less than 5% in the 1960 to 32.7% by 2013 with stable rate around 32-33% in the last five years , cesarean delivery is associated with increased maternal…
- Trial name
- NCT03510130
- Testing
- Routine leg movement
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cesarean Section
Factors Influencing Cesarean Section Rate: Does the Audit Still Work?
To elucidate the audit's effect on caesarean section rate, and also define the factors influencing the caesarean section rate. From Jan 2007 , pregnant women who delivered in a medical center will be included retrospectively in…
- Trial name
- NCT01808807
- Where
- Taiwan
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Perinatal Problems, Mental Depression
Effect of Perinatal Emotional Management on Maternal Emotion and Delivery Outcomes
Pregnancy or childbirth is a kind of persistent and strong source of stress for pregnant women. Prenatal and intrapartum negative emotions not only damage the mental health of pregnant women, but also have a negative impact on…
- Conditions
- Perinatal Problems, Mental Depression, Complications; Cesarean Section
- Trial name
- NCT01851187
- Testing
- antenatal psychological intervention, routine prenatal care
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Sudden Unexplained Infant Death, Apnea of Newborn
Advanced Wireless Sensors for Neonatal Care in the Delivery Room
The goals of this observational study is to assess whether a new advanced wireless skin sensor vital sign monitoring system can effectively monitor the vital signs of healthy newborn infants (≥ 35 weeks gestational age).
- Conditions
- Sudden Unexplained Infant Death, Apnea of Newborn, Newborn Morbidity, Newborn Asphyxia
- Trial name
- AWARD (NCT06693817)
- Testing
- Wireless skin sensors vital sign monitoring system, Wired vital sign monitoring system
- Where
- 5 sites in Brazil, Canada and 2 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Guilherme Sant'Anna, MD
Pregnancy
Active Management Of Risk In Pregnancy At Term to Reduce Rate of Cesarean Deliveries
This is a prospective randomized cohort study of obstetric patients from Paley clinic at AEMC and from other affiliated obstetric clinics.
- Trial name
- NCT00598260
- Testing
- induction of labor
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network