Clinical trials: Cessation, Smoking
Cardiovascular Disease
Simplified Cardiovascular Management Study
The goal of this study is to develop, pilot test, and evaluate a highly simplified but guideline-based program for cardiovascular management for application in resource-scarce settings.
- Trial name
- SimCard (NCT01503814)
- Testing
- Simplified cardiovascular disease management
- Where
- 3 sites in China, India
- Volunteers
- 2,086 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Nicotine Dependence, Major Depressive Disorder
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Persons who struggle with depression smoke at high rates and experience low quit rates in treatment. The best way to improve cessation treatment for this underserved population remains unknown.
- Trial name
- NCT02378714
- Testing
- Varenicline, BASC, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Cardiovascular Diseases, Heart Diseases
Chinese Community Smoking Cessation Project
The study has two objectives/aims: Aim 1: To test the efficacy of the intervention among adult smokers with cardiovascular disease, pulmonary disease and diabetes mellitus related illnesses (later modified to Chinese adults with…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases, Diabetes Mellitus
- Trial name
- NCT00139516
- Testing
- self-help, nicotine replacement therapy, smoking cessation
- Sponsor
- University of California, San Francisco
Smoking Cessation
PATH Partnering to Achieve Tobacco-free Health
The overall aim of this 5-year project is to capitalize on the strong theoretical and promising empirical evidence for Acceptance \& Commitment Therapy (ACT) as an intervention for smoking cessation by comparing the effectiveness…
- Trial name
- PATH (NCT01533974)
- Testing
- Acceptance & Commitment Therapy (ACT), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Reduction
The Potential Effect of Avena Sativa L. on Wellness/Wellbeing During Smoking Reduction/Cessation Experience
The purpose of this study is to evaluate the potential effect of Avena Sativa L. on wellbeing during smoking reduction/cessation
- Trial name
- SMOK (NCT04749017)
- Testing
- Experimental product consumption, Control product consumption
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Non Small Cell Lung Cancer
A Study of Alimta/Cisplatin/Gefitinib for Asian Non-smoking Participants With Non Small Cell Lung Cancer
The purpose of this study is to compare two different approaches to treating non-small cell lung cancer (NSCLC) in East Asian never-smoker participants.
- Trial name
- NCT01017874
- Testing
- Pemetrexed, Cisplatin, Gefitinib
- Where
- 12 sites in Hong Kong, Singapore and 3 more
- Volunteers
- 236 people
- Sponsor
- Eli Lilly and Company
Smoking Cessation, Substance Use Disorder
Intensive Referral to Reduce Smoking in Probationers
The purpose of this study is to determine if Intensive Referral Intervention increases motivation to quit cigarette smoking and quitting-related behaviors in probationers and also to determine if Intensive Referral Intervention…
- Trial name
- NCT03042650
- Testing
- Intensive Referral Intervention Group, Standard Practice Facilitated Group
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Nebraska
Smoking Cessation
Effectiveness of Primary Care Nurse-supervised Educational Group Interventions for Giving up Smoking
Background: To analyze the effectiveness of two group interventions for smoking cessa-tion (with support from the app) conducted by primary care nurses.
- Trial name
- NCT07021417
- Testing
- Workshop, Course
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- Universidad de Murcia
Cigarette Smoking
Text Messaging-Based Smoking Cessation Program for Homeless Youth
Unaccompanied homeless youth smoke at much higher rates than non-homeless adolescents and young adults. Many homeless youth smokers are motivated to quit; yet, strategies specifically developed for this vulnerable population are…
- Trial name
- NCT03874585
- Testing
- Group counseling and nicotine replacement, Group counseling, nicotine replacement, and text messaging support
- Where
- 3 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- RAND
Tobacco Use Cessation
Tobacco Cessation Via Doctors of Chiropractic
The purpose of the study is to develop an office-based tobacco intervention for chiropractic patients.
- Trial name
- NCT00386945
- Testing
- Brief counseling (Ask, Advise, Arrange)
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Oregon Research Institute
Smoking Cessation
Progesterone Augmentation of Nicotine Replacement Therapy Study
This will be a double-blind, placebo-controlled, pilot, randomized clinical trial. A total of 50 women who smoke and have regular menstrual cycles will be randomized to either progesterone (200 mgs BID) + Transdermal Nicotine…
- Trial name
- PANS (NCT02685072)
- Testing
- Progesterone (200 mgs BID)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Yale University
Tobacco Use Disorder
Bupropion and Weight Control for Smoking Cessation - 1
The purpose of this study is to determine whether the addition of bupropion (Zyban) to cognitive behavioral therapy (CBT) will enhance longer-term tobacco abstinence in women.
- Trial name
- NCT00006170
- Testing
- Bupropion, weight concerns intervention, smoking cessation intervention
- Where
- United States
- Volunteers
- 349 people
- Sponsor
- University of Pittsburgh
E Cigarette Use
Impact of Aversive Warnings on E-Cigarette Cessation
This project aims to evaluate the effectiveness of aversive visual health warnings on e-cigarette cessation among young adults through a randomized controlled trial, as e-cigarette use among this population has been steadily…
- Trial name
- NCT05892445
- Testing
- Graphic Warning Labels
- Volunteers
- 1,000 people
- Sponsor
- University of California, San Diego
Smoking Cessation
Quit and Fit: A Tobacco Cessation and Energy Balance Pilot for African Americans
The Quit \& Fit intervention will be designed as a 12-week study to promote smoking cessation, increase physical activity levels, and reduce weight gain through regular exercise and healthy nutrition for African American Women…
- Trial name
- Quit and Fit (NCT02103582)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Georgetown University
COPD (Chronic Obstructive Pulmonary Disease)
RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials Cooperative
The study hypothesis is that symptomatic current and former smokers with spirometric values within the normal range (post-bronchodilator FEV1/FVC≥0.70 and post-BD FVC ≥ 70% predicted will still derive symptomatic benefit from…
- Trial name
- RETHINC (NCT02867761)
- Testing
- Indacaterol/Glycopyrrolate
- Where
- 16 sites in United States
- Volunteers
- 780 people
- Sponsor
- University of Michigan
Tobacco Use Cessation, Smoking Cessation
Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized Smokers
This study will implement and test the effectiveness and cost-effectiveness of a tobacco cessation intervention (Academic Detailing + Integrated Tobacco Order Set - AD + ITOS) for adults admitted to the hospital.
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
- Trial name
- NCT01691105
- Testing
- AD + Integrated Tobacco Order Set
- Where
- United States
- Volunteers
- 1,044 people
- Sponsor
- Yale University
Cigarette Smoking
Smoking, Stress, HIV and Mobile Technology
The present investigation aims to address disparities in cigarette use outcomes among Black/African American adults with HIV. The specific aims of this study are: (1) To modify a recently developed, culturally adapted, mobile…
- Trial name
- NCT05709002
- Testing
- MASP+, Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Houston
Tobacco Smoking
Heart Rate Variability Biofeedback for Smoking Cessation
Open trial of heart rate variability biofeedback as an adjunct to individualized smoking cessation counseling (SCT) plus transdermal nicotine replacement patch (NRT) in smokers with elevated emotional distress.
- Trial name
- HRVB-SCT (NCT03972137)
- Testing
- Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback (HRVB), Transdermal Nicotine patch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Acute Coronary Syndrome, Tobacco Use
Integrated Smoking Cessation and Mood Management for ACS Patients
Quitting smoking following acute coronary syndrome can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and independently predicts mortality.
- Trial name
- PACES (NCT03029923)
- Testing
- Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS), Smoking cessation plus Health and Wellness
- Where
- United States
- Sponsor
- The Miriam Hospital
HIV, Tobacco Use
Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya
People with HIV (PWH) smoke tobacco cigarettes and drink alcohol at higher rates than the general population, both in the US and internationally, including low- and middle-income countries.
- Conditions
- HIV, Tobacco Use, Alcohol Use Disorder
- Trial name
- NCT06790342
- Testing
- Cystine, Positively Smoke Free, Standard of Care
- Where
- 2 sites in Kenya
- Volunteers
- 300 people
- Sponsor
- University of Chicago
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