Clinical trials: Chalazion
Chalazion
Efficacy of Intense Pulsed Light in the Treatment of Recurrent Chalazia
The purpose of the present study was to investigate the efficacy of intense pulse light and meibomian glands expression in cases of recurrent chalazion after surgery.
- Trial name
- NCT05070611
- Testing
- IPL-MGX
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chalazion, Dry Eye Syndromes
Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye
The objective of this study is to evaluate the clinical utility, safety and effectiveness of the Manual Mini System compared to standardized warm compress therapy for application of controlled, localized heat therapy in adult…
- Trial name
- NCT00832130
- Testing
- Manual Mini System, iHeat Portable Warm Compress Therapy
- Where
- 11 sites in United States
- Volunteers
- 139 people
- Sponsor
- TearScience, Inc.
Chalazion Unspecified Eye, Unspecified Eyelid, Chalazion Left Eye, Unspecified Eyelid
Chalazion Conservative Treatment Trial
An eyelid stye, or chalazion, is the most common eyelid ailment, and is caused by the blockage of one of the oil secreting glands of the eyelid (meibomian glands).
- Conditions
- Chalazion Unspecified Eye, Unspecified Eyelid, Chalazion Left Eye, Unspecified Eyelid, Chalazion Right Eye, Unspecified Eyelid, Chalazion Both Eyes
- Trial name
- NCT01230593
- Testing
- Hot Compress plus Tobramycin Drops and Ointment, Hot compress plus Tobramycin/Dexamethasone Drops and Ointment, Hot Compresses
- Where
- 3 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- McMaster University
Chalazia, Chalazion
Intralesional Tetracycline Injection in the Treatment of Chalazia
The investigators propose a study to investigate the role of tetracycline injection into chalazia versus observation alone. The investigators hypothesize tetracycline injection will result in a significant decrease in lesion size…
- Trial name
- TET (NCT01763437)
- Testing
- Tetracycline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Chalazion
Is the Use of a Steam Mask an Effective Treatment for Paediatric Chalazion in Comparison to Traditional Warm Compresses?
Is the use of a steam mask an effective treatment for paediatric chalazion in comparison to traditional warm compresses? This study will aim to assess the difference between these two methods.
- Trial name
- NCT07721779
- Testing
- Steam device, Warm Compress
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Sheffield
Chalazion
Therapeutic Efficacy of Intense Pulsed Light in the Treatment of Chalazion
Study method: This test screened the subjects first, and proposed to include 50 subjects with primary or recurrent eyelid plate gland cysts without obvious surgical indications.
- Trial name
- NCT05512572
- Testing
- IPL, Conservative treatment or excision with curettage
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chalazion
Safety and Efficacy Study of SUN 131 TDS as Compared to Placebo TDS in Adult Patients With a Chalazion
The purpose of this study is to evaluate the efficacy and safety of SUN-131 1.5% TDS as compared with placebo TDS in the treatment of chalazion based on the proportion of subjects that have complete response.
- Trial name
- NCT02338648
- Testing
- SUN-131 1.5% TDS
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Senju USA, Inc.
Chalazion, Dry Eye Syndromes
Evaluation of Screening Methods for Treatment of Meibomian Gland Dysfunction
The objective is to evaluate the feasibility of using additional screening methods to optimize effectiveness outcomes with the LipiFlow System for application of heat and pressure therapy in adult patients with chronic cystic…
- Trial name
- NCT01202747
- Testing
- LipiFlow System
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- TearScience, Inc.
Chalazion
Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study
Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.
- Trial name
- CTS (NCT02025023)
- Testing
- 5-fluorouracil Injection, Triamcinolone Acetonide, Incision and Curettage
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
Chalazion
Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion
To study the effectiveness and safety of IPL treatment for Chalazion
- Trial name
- NCT07039461
- Testing
- OptiLIGHT
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Chalazion
Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion
To study the effectiveness and safety of IPL treatment for Chalazion
- Trial name
- NCT07405138
- Testing
- Active IPL
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Lumenis Be Ltd.
Chalazion, Hordeolum
Pediatric Zylet Safety and Efficacy Study
A multicenter study to evaluate the safety and efficacy of Zylet compared to vehicle in children aged 0-6 for the management of lid inflammation (chalazion/hordeolum)
- Trial name
- NCT00420628
- Testing
- loteprednol etabonate/tobramycin opthalmic suspension, vehicle
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Bausch & Lomb Incorporated
Chalazion
Probiotics for Treatment of Chalazion in Adults
There is growing evidence encouraging probiotics use in several diseases. The aim of the investigator's study is to define the possible beneficial impact of probiotics on adults suffering from chalazia.
- Trial name
- NCT04342507
- Testing
- conservative treatment, probiotics
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Molise
Chalazion
Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery
This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery.
- Trial name
- SEVO-PED (NCT07450495)
- Testing
- Sevoflurane
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Chalazion
Probiotics for Chalaziosis Treatment in Children
There is growing evidence encouraging the use of probiotics in many conditions in children. The aim of the investigator's study is to define the possible beneficial impact of probiotics on paediatric patients affected by…
- Trial name
- NCT04322500
- Testing
- probiotics, conservative treatment
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Molise
Pediatric Chalazia
Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia
Participants enrolled into the study will be prescribed twice daily warm compresses for 8 weeks and randomly allocated (1:1:1) to receive either 1) Oral omega-3 supplementation and standard eyelid cleanser, 2) Anti-Demodex eyelid…
- Trial name
- CH01 (NCT07496515)
- Testing
- Omega-3 supplement, Warm compress, Standard eyelid cleanser
- Volunteers
- 168 people
- Sponsor
- Jaeb Center for Health Research
Chalazion
Safety and Efficacy Study of SUN-131 Transdermal System (TDS) as Compared to Placebo TDS in Patients With a Chalazion
This protocol for SUN-131 1.5% TDS is developed for the treatment of chalazion. SUN-131 1.5% TDS is designed for local delivery of a corticosteroid, to the upper or lower eyelid.
- Trial name
- SUNRISE (NCT03248440)
- Testing
- SUN-131 1.5% TDS
- Where
- 65 sites in United States
- Volunteers
- 263 people
- Sponsor
- Senju USA, Inc.