Clinical trials: Change; Mental
Schizophrenia, Depression
Neuromodulation in Depressed and Schizophrenic Patients - Changing MEP (Muscle Evoked Potentials) by tDCS (Transcranial Direct Current Stimulation)
Muscle evoked potentials (MEP) are supposed to different in schizophrenic and depressed patients, compared to a sample of healthy volunteers.
- Trial name
- NCT01150734
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Autism Spectrum Disorders
A Study of a Developmental,Individual-Difference,Relationship-Bases/Floortime Intervention for Children With Autistic
Thirty eight autistic spectrum disorder children age 2-6 years recruited into the study. The new treatment intervention is based on the DIR Model. Parents will be coached at the start and then every 3-4 months for 1 year.
- Trial name
- DIR (NCT00954213)
- Testing
- DIR/Floortime parent intervention
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Psychotic Disorders, Schizophrenia
Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis
In the last decade cognitive behavioural therapy (CBT) approaches for patients with schizophrenia have been developed, which where especially designed to reduce severity of positive symptoms, readmission rates, treatment…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- mCBT (NCT00465920)
- Testing
- modified cognitive behavioural therapy (mCBT)
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Cologne
Pain, Anxiety
The Effect of Cartoon Watching During Central Venous Catheter Dressing Changes in Children With Cancer
Many medical interventions, including dressing change of central venous catheters, can cause anxiety and pain in children with cancer.
- Trial name
- NCT05301374
- Testing
- Watching Cartoon
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Mehmet Akif Ersoy University
Psychological Distress, Malnutrition, Child
Transforming Health and Resilience in Vulnerable Environments: Mental Health, Psychosocial Support, and Climate-Smart Farming in Nakivale
The study aims to evaluate if enhancing the mental health of refugee mothers can make them better able to implement new farming methods that are meant to improve food security in the face of climate change.
- Conditions
- Psychological Distress, Malnutrition, Child, Dietary Deficiency, Mental Health
- Trial name
- THRIVE (NCT06425523)
- Testing
- Home Gardening Intervention (HGI), Self-Help Plus (SH+), Enhanced Usual Care (EUC)
- Where
- Uganda
- Volunteers
- 904 people
- Sponsor
- Uppsala University
Multiple Sclerosis
Jacobson's Progressive Muscle Relaxation for Fatigue and Kinesiophobia in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic neurological condition that can cause fatigue and fear of movement (kinesiophobia), which may interfere with daily activities and participation in rehabilitation.
- Trial name
- JPMRT (NCT07854691)
- Testing
- Jacobson's Progressive Muscle Relaxation Technique (JPMRT), Routine Care
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Al-Zaytoonah University of Jordan
Depression, Anxiety Disorders
Understanding the Person, Exploring Change Across Psychotherapies
Identifying predictors and understanding mechanisms of change will inform referral to psychotherapy, triage and right-siting by helping clinicians to understand how their patients are likely to benefit from clinical…
- Trial name
- Xchange (NCT04106713)
- Testing
- Individual Psychotherapy, Internet-delivered Cognitive Behavioural Therapy (iCBT), Group Cognitive Behavioural Therapy (group CBT)
- Where
- Singapore
- Volunteers
- 250 people
- Sponsor
- Institute of Mental Health, Singapore
Diabetes (DM), Diabetes Mellitus
Changes in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict App
The goal of this controlled pre-post-trial is to test the Accu-Chek SmartGuide continuous glucose monitoring (CGM) system and whether its predictive features provide additional benefits for adults with type 1 diabetes or insulin…
- Conditions
- Diabetes (DM), Diabetes Mellitus, Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
- Trial name
- NCT07814508
- Testing
- SmartGuide CGM with Predictive Features
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- FIDAM RDC
Schizophrenia, Chronic Illness
Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)
This project evaluates the implementation and effectiveness of a care model to improve treatment for schizophrenia within the context of diverse VA practices and priorities.
- Conditions
- Schizophrenia, Chronic Illness, Weight Gain, Psychotic Disorder
- Trial name
- EQUIP-2 (NCT00137280)
- Testing
- Collaborative Chronic Illness Care Model
- Where
- 8 sites in United States
- Volunteers
- 1,067 people
- Sponsor
- VA Office of Research and Development
Bulimia Nervosa, Binge Eating Disorder
Using Visual Feedback to Influence Rapid Response in the Treatment of Eating Disorders
This study has two aims: 1) to test the validity of an eating disorder symptom checklist against an established clinical interview; and 2) to examine whether providing eating disorder patients with visual graphs of their symptom…
- Trial name
- NCT02940613
- Testing
- Visual feedback of symptom frequency
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Insomnia, Major Depressive Disorder
Using Sleep Wearables to Adapt Cognitive-behavioral Therapy for Insomnia in the Context of Depression (CBTiA)
This study aims to better adapt cognitive behavioral therapy for insomnia (CBTi) for people with comorbid depression by using objective sleep measures to tailor the behavioral interventions components of CBTi.
- Conditions
- Insomnia, Major Depressive Disorder, Persistent Depressive Disorder
- Trial name
- CBTiA (NCT05990855)
- Testing
- eCBTi-obj, eCBTi-subj
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University of Ottawa
Multiple Sclerosis, Cognitive Impairment
Neurocognitive Changes in Patients With Remitting Relapsing Multiple Sclerosis Treated With Natalizumab
Cognitive impairment is seen in about half of patients with relapsing remitting MS. Our knowledge about long term development of cognitive performance under natalizumab therapy is limited.
- Trial name
- NCT01250678
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Cantonal Hospital of St. Gallen
Dementia
Study to Evaluate the Effect of Megestrol Acetate in Weight Loss in Dementia Patients
The purpose of this study is to demonstrate the efficacy of megestrol acetate in the gain of body weight in patients with primary or mixed Dementia with a weight loss.
- Trial name
- NCT00503516
- Testing
- Megestrol acetate
- Where
- Spain
- Volunteers
- 39 people
- Sponsor
- Rottapharm Spain
Physical Activity, Exercise
Goal Setting to Promote Physical Activity Adherence in Midlife Adults
Engaging in regular physical activity during midlife is a key lifestyle behavior associated with reduced risk for Alzheimer's disease and related dementias (AD/ADRD).
- Trial name
- NCT05980052
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Depression, Unipolar
Whole-body Hyperthermia for Moderate to Severe Depressive Disorder
The primary aim of this study is to investigate the effectiveness of whole-body hyperthermia in addition to standard medical care in comparison to standard medical care alone on depressive symptom severity in patients with…
- Trial name
- HYPE2 (NCT03906149)
- Testing
- Whole-body hyperthermia + standard medical care, Standard medical care
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Universität Duisburg-Essen
Stress Disorders, Post-traumatic
Information Processing Modification in PTSD (Oct. 18)
The purpose of this study is to determine whether a computerized intervention designed to change the nature of attention biases will be effective in reducing the symptoms of post traumatic stress disorder (PTSD) in American…
- Trial name
- NCT00601952
- Testing
- Attention Bias Modification (ABM), Attention Control Condition (ACC)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- San Diego State University
Autism Spectrum Disorder, Intellectual Disability
Heart Rate Informed Changes in Care for Non-Communicating Patients
The overarching aim is to generate knowledge to reduce incidence of pain in non-verbal patients' everyday life. The trial will 1) evaluate how HR can be used to identify potentially painful care procedures that should be…
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Communication, Nonverbal
- Trial name
- NCT05738278
- Testing
- HR-informed change in routine, Delayed HR-informed specific change in routine
- Where
- 2 sites in Norway
- Volunteers
- 38 people
- Sponsor
- University of Oslo
Hepatic Encephalopathy, HE
Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.)
The purpose of this study is to evaluate whether the use of polyethylene glycol is superior and more safe in treating hepatic encephalopathy compared to lactulose and also to determine if treatment with polyethylene glycol will…
- Conditions
- Hepatic Encephalopathy, HE, Cirrhosis, Altered Mental Status
- Trial name
- HELP (NCT01923376)
- Testing
- Lactulose, Polyethylene Glycol 3350
- Where
- United States
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Childhood Obesity, Overweight and Obesity
Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
The main purpose of the present study is to perform a 10 weeks dietary intervention study with a follow-up for 52 weeks in children from 7-14 years of age with overweight or obesity.
- Conditions
- Childhood Obesity, Overweight and Obesity, Adolescent Obesity, Adolescent Overweight
- Trial name
- COPE (NCT04522921)
- Testing
- Diet with a higher amount of protein (25E% per day), Increased follow-up contact after the 10-week intervention, Diet with a lower amount of protein (15E% per day)
- Where
- 2 sites in Denmark
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Schizophrenia
Study to Assess Adverse Events and Change in Disease Activity of Oral Cariprazine Capsules in Adult Participants With Schizophrenia
Schizophrenia is a common and severe psychiatric illness characterized by extreme disturbances of cognition and thought, affecting language, perception and sense of self.
- Trial name
- 509 JPN Schz (NCT05368558)
- Testing
- Cariprazine
- Where
- 52 sites in Japan, Taiwan
- Volunteers
- 34 people
- Sponsor
- AbbVie
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.