Clinical trials: Change; Mental
Mental Health
Study of Individual Neurocognitive Changes Associated With the Training of the Working Memory.
8 participants including 2 pilots. The 2 pilot participants will each execute an MRI acquisition session in order to adjust the experimental paradigm
- Trial name
- SAMPLEX (NCT07851051)
- Where
- France
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Alcohol Drinking, Chronic Inflammation
30-to-90 Day Challenge: Effects of Alcohol Cessation on Health Outcomes
The objective for this project is to determine whether how certain behavioral and health functions change in persons with heavy drinking when they stop (or reduce) drinking for 30 days, and whether changes continue for up to 90…
- Conditions
- Alcohol Drinking, Chronic Inflammation, Neurocognitive Dysfunction, Liver Diseases
- Trial name
- NCT03353701
- Testing
- Contingency Management (CM)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Florida
Major Depressive Disorder
Functional and Metabolic Changes in the Course of Antidepressive Treatment
The study will investigate functional and metabolic changes in the course of antidepressive treatments. The investigators will apply different imaging methods to investigate the effects of antidepressive interventions on resting…
- Trial name
- NCT02099630
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
Cannabis Dependence
Neural Indices Associated With Relapse in Cannabis Dependence
The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired…
- Trial name
- NCT02801422
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Diabetes, Obesity
Healthy Lifestyles for Mentally Ill People Who Have Experienced Weight Gain From Their Antipsychotic Medications
This program aims to help Veterans who take antipsychotic medications lose weight. The investigators use a program based on the American Diabetes Association's "Diabetes Prevention Program," and the investigators have modified it…
- Conditions
- Diabetes, Obesity, Weight Gain
- Trial name
- MAMAO (NCT00344500)
- Testing
- Behavioral Weight Loss Program
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- VA Office of Research and Development
Depression, Major Depressive Disorder
Diet and Depression
This study is a pilot open label crossover trial to assess the feasibility and acceptability of reducing ultra- processed foods (UPF) in a personalized manner from the diets of patients with major depressive disorder who eat a…
- Conditions
- Depression, Major Depressive Disorder, Weight Gain, Obesity
- Trial name
- NCT06252701
- Testing
- Reduction of Ultra-processed foods
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Developing a Culturally Adapted Intervention for Latino Youth Transitioning to Adulthood
The purpose of this study is to evaluate the acceptability, feasibility (e.g., satisfaction, completion rate, barriers to recruitment, treatment fidelity) of the culturally refined Launching! to Adulthood (¡Iniciando! la Adultez)…
- Trial name
- NCT06107972
- Testing
- Launching! to Adulthood (¡Iniciando! la Adultez) program
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The University of Texas Health Science Center, Houston
Schizophrenia, Schizoaffective Disorder
Decision Aid to Facilitate Shared Decision Making During Treatment in Schizophrenia
We hypothesize that the use of a visual decision aid tool to educate patients regarding potential harm with respect to weight gain with olanzapine versus perphenazine can lead to better shared decision making by patients…
- Trial name
- NCT01420575
- Testing
- Visual Decision Aid and Shared Decision Making Model, Usual Care
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- VA Nebraska Western Iowa Health Care System
Burns, Virtual Reality
Virtual Reality and Coping with Procedural Pain in Burn Patients
The main aim of the project is to reduce the feeling of procedural pain (when changing bandages) in burn patients through a developed and pilot-verified application for virtual reality (hereinafter VR).
- Conditions
- Burns, Virtual Reality, Anxiety, Pain
- Trial name
- VRZPB (NCT06596837)
- Testing
- virtual reality
- Where
- Czechia
- Volunteers
- 71 people
- Sponsor
- Martin Zielina
Major Depression
Changes of Functional Connectivity After rTMS in Depression
In order to explore the effect of repetitive TMS, which has shown to be effective in intractable depression, we will examine resting-state, default-mode network functional connectivity in patients with major depression.
- Trial name
- NCT01325831
- Testing
- repetitive transcranial magnetic stimulation(rTMS)
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Yonsei University
Dementia
Changing Talk to Reduce Resistiveness to Care
The investigators are interested in reducing problem behaviors of nursing home residents with dementia that make providing care difficult. The investigators call these behaviors resistiveness to care.
- Trial name
- NCT01324219
- Testing
- Staff, Resident
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- University of Kansas Medical Center
Major Depressive Disorder
Biochemical Brain Changes Correlated With The Antidepressant Effect Of Thyroid Hormones
We propose to investigate structural and biochemical brain abnormalities in depressed subjects, and the relationship between the presence of such abnormalities and treatment outcome.
- Trial name
- NCT00562367
- Testing
- Cytomel (liothyronine)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
A Longitudinal Follow-up Imaging Study on Children and Adolescents With Autism Spectrum Disorder
The significance of this project is the first longitudinal study to investigate the changes of neurocognitive functions of children and adolescents with ASD and to identify the potential neuroimaging endophenotype (biomarkers)…
- Trial name
- NCT02719067
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- National Taiwan University Hospital
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ankylosing Spondylitis
The Relationship Between Abnormal Modified Schober Index and Demographic Characteristics and Clinical Variables
This study will aim to compare ankylosing spondylitis (AS) participants with abnormal modified Schober index (AMSI) versus AS participants with normal modified Schober index (NMSI) in pain, morning stiffness, balance…
- Trial name
- NCT05589922
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Mustafa Kemal University
Alcoholic Intoxication, Alcohol-Related Disorders
Longitudinal Changes in the Oral and Gut Microbiome of Individuals With Alcohol Dependence
Background: Many bacteria live in the gut. The gut is the tube that moves food from the mouth through the stomach to the intestines. Heavy alcohol use disturbs these bacteria.
- Trial name
- NCT02911077
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Obsessive - Compulsive Disorder
Feasibility and Efficacy Trial of a Culturally Adapted Guided Self-Help CBT Manual for OCD
This randomised controlled trial (RCT) aims to assess the feasibility, acceptability, and preliminary efficacy of a culturally adapted, guided self-help cognitive behaviour therapy (CBT) manual specifically designed for…
- Trial name
- NCT07239401
- Testing
- Culturally adapted Guided Self-Help OCD Manual
- Volunteers
- 108 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Mental Health, Aggressive Childhood Behavior
Mental Health Prevention Among Preschool Children Using a Culturally Adapted Version of ICPS
Mental health in Chilean children and families is an urgent public health problem. Prevalence of psychiatric disorders among children between 4 and 11 years old is 27.8%, a higher percentage than was found in adolescents between…
- Conditions
- Mental Health, Aggressive Childhood Behavior, Problem Behavior, Social Behavior
- Trial name
- NCT03383172
- Testing
- I Can Problem Solve (ICPS) Program
- Where
- Chile
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Fundación San Carlos de Maipo
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
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