Clinical trials: Chemotherapy Induced Pain Neuropathy
Peripheral Nervous System Diseases, Pain Management
Self-Guided Online Cognitive Behavioral Strategies for Chemotherapy-Induced Peripheral Neuropathy
The purpose of this pilot randomized wait-list controlled trial is to test the efficacy of an online cognitive behavioral pain management website called Proactive Self-Management Program for Effects of Cancer Treatment (PROPSECT)…
- Conditions
- Peripheral Nervous System Diseases, Pain Management, Self Management
- Trial name
- SONICS (NCT02760654)
- Testing
- Proactive Self Management Program for Effects of Cancer Treatment
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Chemotherapy Induced Peripheral Neuropathy
Effects of Telerehabilitation Versus Clinical Rehabilitation on Chemotherapy Induced Peripheral Neuropathy
The aim of this study is to determine the comparative effects of telerehabilitation versus clinical rehabilitation on neuropathic pain, physical function and quality of life in Chemotherapy induced peripheral neuropathy patients.
- Trial name
- NCT06696976
- Testing
- Telerehabilitation, Clinical rehabilitation
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy
Pain, Psychological, and Endocannabinoid Responses to Yoga in Breast Cancer Survivors With Chemotherapy-induced Neuropathic Pain
This study evaluates the acute effect of aerobic exercise and yoga on pain, plasma levels of endocannabinoids, and mood (i.e., mood disturbance and anxiety). Participants will complete three separate sessions on different days.
- Conditions
- Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Neuropathic Pain
- Trial name
- NCT04075097
- Testing
- Aerobic exercise, Iyengar yoga
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison
Neuropathic
Pulsed Electromagnetic Field Therapy to a Tailored Exercise Program for Patients Suffering From Chemotherapy-induced Neuropathy Related to Breast Cancer
This research studied the usefulness of a targeted intervention designed to manage chemotherapy-induced symptoms, particularly focusing on pain relief, balance deviations and functional improvements.
- Trial name
- PEMFTEPCHIN (NCT06947577)
- Testing
- pulsed electromagnetic field (PEMF) therapy and a tailored exercise program (TEP), Tailored Exercise Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Breast Cancer, Colorectal Cancer
Chemotherapy-Induced Peripheral Neuropathy Survey
The goal of this research study is to learn more about pain and other symptoms that patients may experience while receiving chemotherapy treatment with platinum agents, taxanes, and/or bortezomib.
- Conditions
- Breast Cancer, Colorectal Cancer, Myeloma, Chemotherapy-induced Peripheral Neuropathy
- Trial name
- NCT01016028
- Testing
- Questionnaire, Sensory Tests, Interview
- Sponsor
- M.D. Anderson Cancer Center
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Breast Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT03124511
- Testing
- Surgery for breast cancer
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Danish Pain Research Center
Oxaliplatin-induced Peripheral Neuropathy, Chemotherapy
Auricular Acupressure : Improves Oxaliplatin-induced Peripheral Neuropathy
Oxaliplatin-induced peripheral neuropathy (OIPN) is a common adverse effect that becomes worse as the drug dose accumulation impacts cancer patients' daily activities and quality of life.The result of this study will determine…
- Trial name
- NCT04751513
- Testing
- auricular acupressure
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Chang Gung Memorial Hospital
Chemotherapy-induced Peripheral Neuropathy
The Role of TRP Channels in CIPN
Part I: Evaluating the increase in dermal blood flow upon topical application of cinnamaldehyde and capsaicin on the fingers in healthy, male volunteers.
- Trial name
- NCT04415892
- Testing
- Cinnamaldehyde and capsaicin
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Peripheral Neuropathic Pain, Neurotoxicity
Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage
Background: Docetaxel, the most commonly used drug for the treatment of invasive breast cancer, has been shown to prolong the lives of women with breast cancer and prevent the cancer from spreading or returning.
- Conditions
- Peripheral Neuropathic Pain, Neurotoxicity, Cancer
- Trial name
- NCT01293851
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of Nursing Research (NINR)
Chemotherapy-induced Peripheral Neuropathy, Cancer Survivors
Effectiveness of Online ACT for Pain Interference in Cancer Survivors With Chronic Painful CIPN
Rationale: An average of 30% of adult cancer survivors suffers from chemotherapy-induced peripheral neuropathy (CIPN) ≥ 6 months after completion of chemotherapy, and their quality of life (QoL) is strongly affected due to these…
- Trial name
- QLIPP-CIPN (NCT05371158)
- Testing
- Online intervention
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- Daniëlle van de Graaf
Cancer, Peripheral Neuropathy
Chemotherapy Induced Painful Peripheral Neuropathy Ethosuximide (The CIN-E Study)
This study is a drug trial of ethosuximide as a painkiller if you develop pain as a side effect of chemotherapy. Ethosuximide will be compared against placebo (an inactive substance) to test whether any response is a true effect…
- Trial name
- CINE-E (NCT01278004)
- Testing
- Ethosuximide
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Chemotherapy Induced Peripheral Neuropathy, Breast Cancer Patients
Effects of Sensorimotor Training With Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Patients
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a prevalent and clinically relevant side effect of chemotherapy in breast cancer patients. It occurs in 30-70% of cases. It can cause various sensory and motor symptoms.
- Trial name
- NCT06737926
- Testing
- Sensorimotor Training Exercise, Conventional Exercise Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Breast Cancer, Ovarian Neoplasm
Omega-3 Fatty Acid in Treating Pain in Patients With Breast or Ovarian Cancer Receiving Paclitaxel
Paclitaxel, a widely used chemotherapeutic agent, is associated with several well-known side effects including neuropathy (weakness, numbness and pain) and generalized body aches.
- Conditions
- Breast Cancer, Ovarian Neoplasm, Pain
- Trial name
- NCT01821833
- Testing
- Omega-3 fatty acid, Paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- New Mexico Cancer Research Alliance
Diabetic Neuropathies, Complex Regional Pain Syndrome Type II
The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic Neuropathy
This is a controlled trial designed to determine short- and long-term effects of repeated tDCS on the P300 component of event-related evoked potentials in patients with chronic neuropathic pain due to Complex regional Pain…
- Conditions
- Diabetic Neuropathies, Complex Regional Pain Syndrome Type II, Resistant Peripheral Neuropathic Pain, Chemotherapy Induced Pain Neuropathy
- Trial name
- NCT00815932
- Where
- Israel
- Sponsor
- Soroka University Medical Center
Chemotherapy Induced Peripheral Neuropathy, Chemotherapy Induced Peripheral Neuropathy (CIPN)
Helping Cancer Patients Manage Neuropathy Symptoms From Chemotherapy With a Low-Intensity, Low-Risk Cranial PEMF Device
The goal of this clinical trial is to examine a low-intensity, low-risk cranial PEMF device and its effectiveness with helping cancer patients manage neuropathy symptoms from chemotherapy.
- Conditions
- Chemotherapy Induced Peripheral Neuropathy, Chemotherapy Induced Peripheral Neuropathy (CIPN), Chemotherapy Induced Pain Neuropathy, Chemotherapy Induced Neuropathic Pain
- Trial name
- NCT07061769
- Testing
- SHIFT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- FluxWear, INC
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Lung Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT02960971
- Testing
- Thoracic surgery for lung cancer
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Danish Pain Research Center
Pain, Peripheral Neuropathy
The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pain Resulting From Chemotherapy Treatment
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting side effect of many chemotherapeutic agents including vincristine, paclitaxel, cisplatin, oxaliplatin, bortezomib and ixabepilone.
- Conditions
- Pain, Peripheral Neuropathy, Neuropathic Pain
- Trial name
- TTX-CINP-201 (NCT01655823)
- Testing
- Tetrodotoxin
- Where
- 23 sites in United States
- Volunteers
- 125 people
- Sponsor
- Wex Pharmaceuticals Inc.
Neuropathy, Pain
Pregabalin in CIPN
The investigators seek to investigate certain patient characteristics that would predict the response to a currently approved analgesic, pregabalin, in patients with chronic pain due to nerve damage caused by chemotherapy.
- Trial name
- NCT02394951
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Chemotherapy-induced Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain
To be eligible for the trial, subjects must have ongoing moderate to severe neuropathic pain related to a prior course of platinum and/or taxane chemotherapy and have no clinical evidence of actively progressive disease.
- Trial name
- NCT05359133
- Testing
- Tetrodotoxin
- Where
- 15 sites in United States
- Volunteers
- 35 people
- Sponsor
- Wex Pharmaceuticals Inc.
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Chinese Medicinal Component Relieves CIPN and Mitochondria Function
A randomized controlled trial was designed and conducted to confirm whether oral administration of the herb Moutan Cortex, which contains paeonol, can alleviate peripheral neuropathy in paclitaxel-treated cancer patients.
- Trial name
- NCT07693374
- Testing
- Moutan cortex
- Where
- Taiwan
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University