Clinical trials: Chemsex
Hypersexuality, Compulsive Sexual Behavior
Effectiveness of ACT for Problematic Chemsex
Investigation of the efficacy of Acceptance and Commitment Therapy (ACT) for the psychological treatment of problematic chemsex.
- Conditions
- Hypersexuality, Compulsive Sexual Behavior, Sexualized Drug Use (Chemsex)
- Trial name
- ChemACT (NCT06406296)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Europea de Madrid
Chemsex
Effectiveness of tDCS on Reducing Craving in Patients Practicing Chemsex: a Single-center, Double-blind, Randomized Controlled Pilot Trial
The aim of this research is to evaluate the efficacy of a new treatment for chemsex or "chemical sex", the use of psychoactive substances to modify sexual experience and performance.
- Trial name
- CHEMSTIM (NCT05945199)
- Testing
- tDCS, Assessment of risk behaviours, Scales
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
ChemSex Users for YMSM
Comprehensive Assessment in a Longitudinal Study on Young Men Who Have Sex With Men Attracting to chemseX-2
CLYMAX is a two-phase observational study that assess multiple aspects of chemsex and young men who have sex with men (YMSM). Phase I of the study (CLYMAX,IRB No.
- Trial name
- NCT06741306
- Testing
- Group1
- Where
- 2 sites in Thailand
- Volunteers
- 150 people
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Behavior
A Chatbot to Reduce Chemsex and HIV-related Risk Behaviors Among Men Who Have Sex With Men
The goal of this clinical trial is to investigate whether receiving chatbot-delivered stage-of-change-tailored online interventions is effective in reducing chemsex among men who have sex with men in Hong Kong.
- Trial name
- NCT07472582
- Testing
- Chatbot-delivered online interventions and online videos, Online videos only
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV Prevention, Substance Use
Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons Who Engage in Chemsex or Substance Use in Thailand
The study evaluates the integration of a sexual pleasure-based approach into harm reduction services for MSM and transgender persons engaging in chemsex or substance use in Thailand, using the "Pleasuremeter" tool to improve…
- Conditions
- HIV Prevention, Substance Use, Mental Health, Sexually Transmitted Infections (STIs)
- Trial name
- PLEASURE (NCT07509853)
- Testing
- Pleasuremeter-guided qualitative interview, Pleasuremeter-based sexual pleasure discussion integrated with harm reduction services
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
HIV Prevention, Substance Use
Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation Study
This study evaluates the pre-implementation phase of a host-led harm reduction model for men who have sex with men (MSM) engaging in chemsex in Bangkok, Thailand, focusing on understanding harms, contexts, and needs to develop a…
- Conditions
- HIV Prevention, Substance Use, Mental Health, Sexually Transmitted Infections (STIs)
- Trial name
- HAMMOCK (NCT07512869)
- Testing
- Self-administered questionnaire assessment, Semi-structured in-depth interviews (IDIs), Development and refinement of harm reduction model
- Where
- Thailand
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Hypersexuality, Compulsive Sexual Behavior
Acceptance and Commitment Therapy for Problematic Chemsex
Investigation of the efficacy of Acceptance and Commitment Therapy (ACT) for the psychological treatment of problematic chemsex. As a pilot study, the intervention will be tested in a small group.
- Conditions
- Hypersexuality, Compulsive Sexual Behavior, Sexualized Drug Use (Chemsex)
- Trial name
- NCT06408545
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Universidad Europea de Madrid
Substance Use
The Use of Cognitive Mindfulness for Chemsex
Title of research: A preliminary RCT of an online mindfulness-based cognitive intervention for Chemsex Research aim: To determine how an online mindfulness-based cognitive intervention, might reduce Chemsex engagement, risky…
- Trial name
- NCT05929040
- Testing
- mindful cognitive intervention
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- London Metropolitan University
Pharmacokinetic Interactions, HIV
Clinical Trial to Evaluate Pharmacological Interactions Between γ-hydroxybutyrate (GHB) and Cobicistat
Gamma-hydroxybutyric acid (GHB) is a popular "party drug" because it is inexpensive and easy to ingest. The calming and euphoric effects of GHB in low doses have given the drug the nickname "liquid ecstasy".
- Trial name
- GHB_Cobi (NCT04322214)
- Testing
- Cobicistat 150 MG, GHB
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
ChemSex Users for YMSM, ChemSex Users
Comprehensive Assessment in a Longitudinal Study on Young Men Who Have Sex With Men Attracting to chemseX
The study is a two-phase observational study that assess multiple aspects of study and young men who have sex with men (YMSM). Phase I of the study will be a cross-sectional descriptive study using a mixed methods data collection…
- Trial name
- CLYMAX (NCT05559658)
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Substance Use, HIV Prevention
Pre-implementation Study to Develop Trans-tailored Services for Transgender Persons in Relation to chemsEX
The study is a pre-implementation cross-sectional study exploring chemsex behaviors among transgender persons and gathering perspectives from multiple stakeholders to inform the development of transgender-tailored harm reduction…
- Conditions
- Substance Use, HIV Prevention, Sexually Transmitted Infections (STIs)
- Trial name
- T-REX (NCT07505875)
- Testing
- Understanding of chemsex patterns, impacts, and service needs among transgender persons
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Methamphetamine Use Disorder
Ketamine-Assisted Recovery for Methamphetamine Use Disorder & HIV
The goal of this clinical trial is to learn whether it is possible to use intramuscular (IM) ketamine in combination with psychotherapy to treat moderate-to-severe methamphetamine use disorder (MeUD) in publicly insured patients…
- Trial name
- KARE (NCT06538285)
- Testing
- Ketamine, Psychotherapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Nicky Mehtani, MD, MPH
Harm Reduction
Harm Reduction Strategies for Gay, Bisexual and Other Men Who Have Sex With Men Engaging in Chemsex
This study is examining the usability and effectiveness of an innovative mobile app that integrates harm reduction strategies into the existing pre-exposure prophylaxis (PrEP) intake and adherence app, with an overarching goal to…
- Trial name
- NCT06187415
- Testing
- Mobile app to reduce harm of chemsex
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Psychoactive Substance Use, Mood Disorders
PrEP and Consumptions
HIV pre-exposure prophylaxis (PrEP) with Truvada®, a combination of two antiretrovirals (tenofovir \& emtricitabine) is a prevention strategy for HIV-negative people at high risk of acquiring HIV.
- Trial name
- PrEP (NCT03449771)
- Testing
- self-administered questionnaire
- Where
- 5 sites in France
- Volunteers
- 237 people
- Sponsor
- University Hospital, Montpellier
Recreational Drug Use
Chemsex Engagement and HIV Biomedical Prevention in MSM
HIV biomedical prevention through treatment-as-prevention (TasP) and pre-exposure prophylaxis (PrEP) is highly efficacious for reducing HIV transmission risk.
- Trial name
- NCT05031832
- Testing
- HIV test
- Where
- Hong Kong
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chemsex
Acceptance and Commitment Therapy for Chemsex
Quasi-randomized control trial of acceptance and commitment therapy (ACT) for chemsex.
- Trial name
- ACT-for-chemse (NCT06980974)
- Testing
- ACT-for-chemsex, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Men Having Sex With Other Men
HIV Prevention During Chemsex
In 2016, the number of discoveries of HIV seropositivity is estimated at about 6000 in France. Men who have sex with men (MSM) account for 44% of these infections (68% in the Occitanie region).
- Trial name
- Chemsex (NCT03956758)
- Testing
- Semi-directed interview
- Sponsor
- University Hospital, Montpellier
HIV
Diagnostic of Human Immunodeficiency Virus (HIV) and Other Sexual Transmission Diseases (STD) in High Risk Populations: Men Who Have Sex With Men (MSM) Users of Chemsex
The main objective is to offer diagnostic tests for HIV, HCV and other STD in the risk group of men having sex with men (MSM) users of Chemsex
- Trial name
- Care_ChemS (NCT03546140)
- Volunteers
- 500 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Drug Dependence
Drug Use During Sex and Its Impact on Taking PrEP (Pre-Exposure Prophylaxis) : CONSUME
This is a cross-sectional, single-center observational study conducted from October 2020 to March 2021 in Ile de France at the infectious disease of CHU Bichat (PrEP and CeGIDD(Free Center for Information, Screening and Diagnosis…
- Trial name
- CONSUME (NCT04709016)
- Testing
- self-questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris