Clinical trials: Chest CT Scan
Acute Respiratory Distress Syndrome (ARDS)
Accuracy of the Chest Radiograph for the Diagnosis of Acute Respiratory Distress Syndrome
The presence of bilateral lung infiltrates on chest imaging is a mandatory criterion for the diagnosis of acute respiratory distress syndrome (ARDS).
- Trial name
- CT 4 ARDS (NCT07400445)
- Where
- France
- Volunteers
- 277 people
- Sponsor
- Poitiers University Hospital
Lung Adenocarcinoma
Radiomics-based Prediction Model of Tumor Spread Through Air Space in Lung Adenocarcinoma
Spread through air space (STAS) has been reported as a negative prognostic factor in patients with lung cancer undergone sublobar resection. Its preoperative assessment could thus be useful to customize surgical treatment.
- Trial name
- NCT04893200
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Roma La Sapienza
Solitary Pulmonary Nodule, Lung Neoplasms
Radiomics for Distinguishing Benign and Malignant Lung Nodules
Differentiating between benign (non-cancerous) and malignant (cancerous) pulmonary nodules is a critical step in determining appropriate patient management and cancer treatment planning.
- Conditions
- Solitary Pulmonary Nodule, Lung Neoplasms, Multiple Pulmonary Nodules
- Trial name
- NCT07852000
- Volunteers
- 255 people
- Sponsor
- Assiut University
Cancer of Pancreas, Cancer of Pelvis
Daily Imaging, Target Identification, and Simulated Computed Tomography-Based Stereotactic Adaptive Radiotherapy Workflow in a Novel Ring Gantry Radiotherapy Device
The investigators propose here to evaluate the feasibility of a novel cone-beam CT (CBCT)-guided online adaptive radiotherapy (ART) workflow on the Halcyon device.
- Conditions
- Cancer of Pancreas, Cancer of Pelvis, Cancer of Abdomen, Cancer of Thorax
- Trial name
- NCT04008537
- Testing
- Ring gantry kV-CBCT combined with linear accelerator
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Washington University School of Medicine
Lung Cancer
Danish Lung Cancer Screening Trial (DLCST)
The trial is a randomised trial comparing annual CT screening for lung cancer with no screening in 4104 smokers and former smokers between the age of 50 and 70 years.
- Trial name
- DLCST (NCT00496977)
- Testing
- annual CT screening
- Where
- Denmark
- Volunteers
- 4,104 people
- Sponsor
- Danish Lung Cancer Group
Acute Myocardial Infarction, Unstable Angina
Exploring the Mechanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and Computational Fluid Dynamics II (EMERALD II) Study
The EMERALD II study is a multinational, multicenter, and retrospective study. ACS patients who underwent CCTA from 1 months to 3 years prior to the event will be retrospectively identified.
- Trial name
- EMERALD II (NCT03591328)
- Testing
- Coronary CT angiography
- Where
- South Korea
- Volunteers
- 429 people
- Sponsor
- Seoul National University Hospital
Pneumonia, Elderly Infection
CT Scan Compared to CXR and LUS in Pneumonia in the Elderly
Introduction: Pneumonia is a leading cause of mortality and a common indication for antibiotic in elderly patients. However, its diagnosis is often inaccurate.
- Trial name
- OCTOPLUS (NCT04978116)
- Testing
- Chest X-Ray (CXR), Low-dose CT scan (LDCT), Lung ultrasonography (LUS)
- Where
- 3 sites in Switzerland
- Volunteers
- 473 people
- Sponsor
- University Hospital, Geneva
Pulmonary Nodules, Multiple
Detection and Volumetry of Pulmonary Nodules on Ultra-low Dose Chest CT Scan With Deeplearning Image Reconstruction Algorithm (DLIR)
evaluate the diagnostic performance of ultra-low dose CT using deep learning-based reconstruction in the detection of pulmonary nodules.
- Trial name
- DLIRTHORAX (NCT04482114)
- Testing
- ULD CT
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lung Cancer, SCLC
Predictive Value of FDG-PET-CT Scans for Patients With Lung Cancer Receiving Concurrent Chemo-Radiation
The objective of the study is to investigate the evolution ofn 18F-deoxyglucose (FDG) uptake and the tumour characteristics determined in the plasma of patients with lung cancer of during and after concurrent radiotherapy and…
- Conditions
- Lung Cancer, SCLC, NSCLC
- Trial name
- FDG-PET lung (NCT00522639)
- Testing
- 18F-deoxyglucose (FDG)
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Maastricht Radiation Oncology
COPD (Chronic Obstructive Pulmonary Disease)
Photon-counting CT in Chest Imaging
Purpose and objective: This project aims to evaluate photon-counting computed tomography (PCCT) quantitative accuracy using COPDGene subjects.
- Trial name
- NCT07031336
- Testing
- Photon-counting CT, Energy-integrating CT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Chest Pain, Myocardial Infarction
The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction
Approximately half of patients with acute chest pain, a very common reason for emergency department visits worldwide, have a cardiac cause.
- Conditions
- Chest Pain, Myocardial Infarction, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- CARMENTA (NCT01559467)
- Testing
- Cardiovascular Magnetic Resonance Imaging, Computed Tomography Angiography
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Lung Neoplasms, Mass Screening
Computed Tomography Screening for Early Lung Cancer, COPD and Cardiovascular Disease in Shanghai, China
Low-dose chest computed tomography (CT) is considered as a screening method for early detection of lung cancer in the population at risk, and it also allows to detect chronic obstructive pulmonary disease (COPD) and…
- Conditions
- Lung Neoplasms, Mass Screening, Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
- Trial name
- NCT03988322
- Testing
- Low-dose CT screening with quantitative assessment and management of imaging biomarkers, Low-dose CT screening with visual assessment and management of imaging biomarkers
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Pulmonary Nodule, Solitary, Lung Cancer
3D Printing for Nodule Localization
Implementation of lung cancer screening using low-dose computed tomography has increased the rate of detection of small peripheral pulmonary nodules.
- Trial name
- NCT04056923
- Testing
- 3D-printing guided, CT-guided, Indocyanine Green
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Wen-zhao ZHONG
Lung Cancer
Low-dose Computed Tomography Screening for Lung Cancer in Relatives With Family History of Lung Cancer
Screening with the use of low-dose computed tomography (LDCT) reduces mortality from lung cancer. Relatives with family history of lung cancer are at increased risk of lung cancer compared to those without a family history in…
- Trial name
- NCT02519972
- Testing
- low dose computed tomography
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Lung Diseases
Effectiveness of Ultra-low-dose Chest CT With AI Based Denoising Solution
The main objective of the study is to evaluate the detection rate of pulmonary conditions, percentage of ionizing radiation dose reduction, and state of image quality of ULDCT coupling with innovative vendor-neutral CT denoising…
- Trial name
- NCT05398887
- Testing
- Low radiation dose CT, Underwent ultra dose chest CT, Artificial Intelligence based model
- Volunteers
- 200 people
- Sponsor
- Intermed Hospital
Non-small Cell Lung Cancer, Pulmonary Nodule, Multiple
Breath Combined With CT for Diagnoses of Pulmonary Nodules
Pulmonary nodules diagnosis using breath test of volatile organic compound (VOC) is in its infancy. The accuracy of VOC analysis in diagnosing malignant pulmonary nodules varies cross the published studies.
- Trial name
- NCT04948047
- Testing
- Pathological examinations as the golden diagnosis criteria, Breath test combined with computed tomography
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Peking University People's Hospital
Sarcoidosis, Pulmonary
SARCOLOWDOSE : Ultra-low Dose CT Scan and MRI in Thoracic Sarcoidosis
The goal of this study is to evaluate the diagnostic agreement between, on the one hand, ultra-low dose CT and MRI with UTE pulse sequences, and on the other hand, standard CT scan, to quantify lung parenchyma patterns in…
- Trial name
- SARCOLOWDOSE (NCT03140644)
- Testing
- Patients with thoracic sarcoidosis
- Where
- 7 sites in France
- Volunteers
- 196 people
- Sponsor
- Rennes University Hospital
Lung Malignancy
Validating Artificial Intelligence Effectiveness Defined Lung Nodule Malignancy Score in Patients With Pulmonary Nodule.
Artificial intelligence (AI) based algorithms have demonstrated increased accuracy in predicting the risk of Lung Cancer among patients with an incidental pulmonary nodule (IPN) on chest radiographs.
- Trial name
- CREATE (NCT05817110)
- Testing
- Participant Cohort
- Where
- 22 sites in Egypt, India and 3 more
- Volunteers
- 712 people
- Sponsor
- AstraZeneca
Thoracic CT-scan, Right Upper Lobe Anatomy
New Measures for Tracheobronchial Anatomy
The right-sided double lumen endobronchial tube (R-DLT) is seldom. The principal cause of reticence for using the R-DLT are the difficult positioning of its lateral orifice in front of the origin of the right upper lobe (RUL) and…
- Conditions
- Thoracic CT-scan, Right Upper Lobe Anatomy, Right Sided Double Lumen Endobronchial Tube
- Trial name
- ATB (NCT02366455)
- Testing
- Measurement of the length of the right main stem bronchus, Measurement of the right upper lobe bronchus antero-posterior angulation
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Laval University
Stage III Non-small Cell Lung Cancer
The Beneficial Value of PET/CT in the Follow-up of Stage III Non-small Cell Lung Cancer Patients
The primary objective of this study is to compare the 3-year overall survival of stage III NSCLC patients during follow-up surveillance with 18F-Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography (18F FDG…
- Trial name
- NVALT31-PET (NCT06082492)
- Testing
- 18F FDG PET/CT, CT scan
- Where
- 27 sites in Netherlands
- Volunteers
- 690 people
- Sponsor
- Radboud University Medical Center