Clinical trials: Chest CT Scan
Thoracic Surgery
Comparing of Microcoil Localization and Hook Wire Localization for Resectable Pulmonary Small Nodules
Both of microcoil localization and hookwire localization have been proved as good preoperative CT(computed tomography)-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to…
- Trial name
- NCT02908646
- Testing
- microcoil localization, hookwire localization
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking University People's Hospital
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Evaluate the Utility of the ProLung Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer
A Study to evaluate the utility of the ProLung Test as an adjunct to CT scan in the diagnosis of lung cancer.
- Trial name
- NCT01958931
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Fresh Medical Laboratories
Lung Neoplasms, Mass Screening
Computed Tomography Screening for Early Lung Cancer, COPD and Cardiovascular Disease in Shanghai, China
Low-dose chest computed tomography (CT) is considered as a screening method for early detection of lung cancer in the population at risk, and it also allows to detect chronic obstructive pulmonary disease (COPD) and…
- Conditions
- Lung Neoplasms, Mass Screening, Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
- Trial name
- NCT03988322
- Testing
- Low-dose CT screening with quantitative assessment and management of imaging biomarkers, Low-dose CT screening with visual assessment and management of imaging biomarkers
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Pulmonary Embolism
Evaluation of the PERC Score and the YEARS Algorithm in the Diagnosis of Pulmonary Embolism in the Emergency Department
The current diagnostic strategy for pulmonary embolism relies on clinical evaluation, followed by D-dimer testing and chest CT angiography. However, this approach leads to overuse of CT angiography.
- Trial name
- EP (NCT07313501)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Lung Cancer, Lung Function Decreased
Use of Dual Energy Computed Tomography in Thoracic Radiotherapy Planning.
This is a prospective observational study aiming: 1) To quantify lung function using perfusion dual energy computed tomography (DECT) and use this information at the time of treatment planning with preferential sparing of…
- Conditions
- Lung Cancer, Lung Function Decreased, Radiation Pneumonitis
- Trial name
- NCT04863027
- Testing
- Thoracic radiotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Therapeutic Procedural Complication
A Comparison the Intubation of a Left Sided Double Lumen Tube and Uniblocker
One-lung ventilation (OLV) is required for the most thoracic surgery to facilitate surgical visualization by collapsing the lung.
- Trial name
- NCT03392922
- Testing
- Uniblocker, Left-sided Double-lumen Tube
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Hospital of Qinhuangdao
Lung Cancer
Lung Cancer Screening Program in Mexico
This prospective study aims to detect early-stage lung cancer using low-dose computed tomography (LDCT) in Mexicans aged 50 or older who are current or former heavy smokers, non-smokers exposed to significant wood smoke, or…
- Trial name
- DETECTO (NCT06535451)
- Testing
- Screening
- Where
- Mexico
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Coronary Artery Disease
Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease
The primary hypothesis is that computed tomography (CT) is superior to invasive coronary angiography (ICA) concerning the primary endpoint MACE (MACE = major adverse cardiovascular event; defined as at least one of the following…
- Trial name
- DISCHARGE (NCT02400229)
- Testing
- Computed tomography angiography (cardiac CT), Invasive coronary angiography (ICA)
- Where
- 20 sites in Austria, Czechia and 13 more
- Volunteers
- 3,546 people
- Sponsor
- Charite University, Berlin, Germany
Pulmonary Nodules, Lung Neoplasms
Longitudinal AI-Assisted Management of Indeterminate Pulmonary Nodules
Patients with indeterminate lung nodules often face a choice between continued CT surveillance and invasive investigation. This trial compares management with or without access to an AI report that matches nodules across real…
- Trial name
- NCT07895277
- Testing
- AI-Assisted Longitudinal CT Assessment and Pulmonary Nodule Management
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Coronary Artery Disease, Chest Pain
CT-FIRST: Cardiac Computed Tomography Versus Stress Imaging For Initial Risk STratification
In patients with chest pain or shortness of breath who are referred for stress imaging tests (either stress echocardiography or stress nuclear testing), the investigators seek to compare impact of using cardiac CT scans of the…
- Conditions
- Coronary Artery Disease, Chest Pain, Coronary Atherosclerosis, Stress Testing
- Trial name
- CT-FIRST (NCT01061398)
- Testing
- Cardiac CT Angiography, Stress Imaging Test (Stress Myocardial Perfusion Study or Stress Echocardiogram)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Walter Reed Army Medical Center
Pulmonary Nodules, Multiple
Detection and Volumetry of Pulmonary Nodules on Ultra-low Dose Chest CT Scan With Deeplearning Image Reconstruction Algorithm (DLIR)
evaluate the diagnostic performance of ultra-low dose CT using deep learning-based reconstruction in the detection of pulmonary nodules.
- Trial name
- DLIRTHORAX (NCT04482114)
- Testing
- ULD CT
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cancer of Pancreas, Cancer of Pelvis
Daily Imaging, Target Identification, and Simulated Computed Tomography-Based Stereotactic Adaptive Radiotherapy Workflow in a Novel Ring Gantry Radiotherapy Device
The investigators propose here to evaluate the feasibility of a novel cone-beam CT (CBCT)-guided online adaptive radiotherapy (ART) workflow on the Halcyon device.
- Conditions
- Cancer of Pancreas, Cancer of Pelvis, Cancer of Abdomen, Cancer of Thorax
- Trial name
- NCT04008537
- Testing
- Ring gantry kV-CBCT combined with linear accelerator
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Washington University School of Medicine
Chest Pain, Myocardial Infarction
The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction
Approximately half of patients with acute chest pain, a very common reason for emergency department visits worldwide, have a cardiac cause.
- Conditions
- Chest Pain, Myocardial Infarction, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- CARMENTA (NCT01559467)
- Testing
- Cardiovascular Magnetic Resonance Imaging, Computed Tomography Angiography
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Chest Wall Deformity, Prominent Lower Rib Cage
Prospective Evaluation of Anterior Aesthetic Rib Cage Remodeling With Osteosynthesis for Lower Anterior Thoracic Prominence
This prospective single-group study will evaluate anterior aesthetic rib cage remodeling with osteosynthesis (ARCO) in adults with anteroinferior rib prominence or deformity.
- Trial name
- NCT07813234
- Testing
- Anterior Aesthetic Rib Cage Remodeling With Osteosynthesis, Chest CT and Spirometry Follow-up
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Research Inc
Lung Cancer
Novel Lung Functional Imaging for Personalized Radiotherapy
The primary objective of this study is to assess the safety and feasibility of personalized radiotherapy with four-dimensional (4D) computed tomography (CT)-based pulmonary ventilation imaging, which selectively avoids…
- Trial name
- NCT02308709
- Testing
- Ventilation image-guided radiotherapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, Davis
Pulmonary Embolism
External Validation of a Deep Learning Based Model for Pulmonary Embolism Detection on Chest CT Scans
The scope of this study is the external validation of an explainable deep learning-based classifier for the diagnosis and detection of pulmonary embolism in computed tomography pulmonary angiography (CTPA) and contrast enhanced…
- Trial name
- NCT05333042
- Where
- Belgium
- Volunteers
- 5,000 people
- Sponsor
- OncoRadiomics
Coronary Artery Disease, Non-significant Coronary Artery Disease
TweeSteden Mild Stenosis Study
Psychosocial factors have been found to be associated with an increased risk for coronary artery disease incidence, progression and worse clinical outcomes.
- Conditions
- Coronary Artery Disease, Non-significant Coronary Artery Disease, Mild Stenosis, Vascular Irregularities
- Trial name
- TWIST (NCT01788241)
- Where
- Netherlands
- Volunteers
- 547 people
- Sponsor
- Tilburg University
Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage III
Dynamic PET/CT Evaluated the Response of Neoadjuvant Anti-PD1 Combination With Chemotherapy for Ⅱa-Ⅲb NSCLC
The neoadjuvant Immune Checkpoint Inhibitor (ICI) or ICI combination with chemotherapy for Non-small cell lung cancer (NSCLC) had induced higher major pathologic response (MPR) and complete pathological response (PCR).
- Conditions
- Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage III, PET/CT
- Trial name
- DYNAPET (NCT04586465)
- Testing
- pembrolizumab, pemetrexed, gemcitabine, cisplatin, carboplatin
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Lung Cancer
Early Lung Cancer Detection Using Computed Tomography
Early detection of lung cancer may improve treatment outcomes. Risk factors have been identified, suggesting a population which might benefit from regular screening.
- Trial name
- NCT00188734
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Acute Coronary Syndrome
Diagnostic Performance of Coronary Calcification Detection on CT Scan
thoracic pain is one of the most frequent reasons for consulting the emergency room. Chest pain can be a sign of different pathologies with a wide range of severity, from life-threatening aortic dissection or myocardial…
- Trial name
- Calci-DT (NCT05538117)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France